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Entry version 60 (08 May 2019)
Sequence version 1 (03 Apr 2007)
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Protein

Protein dispatched homolog 3

Gene

Disp3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCholesterol metabolism, Differentiation, Lipid metabolism, Steroid metabolism, Sterol metabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein dispatched homolog 3By similarity
Alternative name(s):
Patched domain-containing protein 2Curated
RND-type protein RNDEu-21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Disp3By similarity
Synonyms:Kiaa1337, Ptchd2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444403 Disp3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 67CytoplasmicSequence analysisAdd BLAST67
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei68 – 88HelicalSequence analysisAdd BLAST21
Topological domaini89 – 417ExtracellularSequence analysisAdd BLAST329
Transmembranei418 – 438HelicalSequence analysisAdd BLAST21
Topological domaini439CytoplasmicSequence analysis1
Transmembranei440 – 460HelicalSequence analysisAdd BLAST21
Topological domaini461 – 463ExtracellularSequence analysis3
Transmembranei464 – 484HelicalSequence analysisAdd BLAST21
Topological domaini485 – 528CytoplasmicSequence analysisAdd BLAST44
Transmembranei529 – 549HelicalSequence analysisAdd BLAST21
Topological domaini550ExtracellularSequence analysis1
Transmembranei551 – 571HelicalSequence analysisAdd BLAST21
Topological domaini572 – 684CytoplasmicSequence analysisAdd BLAST113
Transmembranei685 – 705HelicalSequence analysisAdd BLAST21
Topological domaini706 – 1137ExtracellularSequence analysisAdd BLAST432
Transmembranei1138 – 1158HelicalSequence analysisAdd BLAST21
Topological domaini1159CytoplasmicSequence analysis1
Transmembranei1160 – 1180HelicalSequence analysisAdd BLAST21
Topological domaini1181 – 1246ExtracellularSequence analysisAdd BLAST66
Transmembranei1247 – 1267HelicalSequence analysisAdd BLAST21
Topological domaini1268 – 1281CytoplasmicSequence analysisAdd BLAST14
Transmembranei1282 – 1302HelicalSequence analysisAdd BLAST21
Topological domaini1303 – 1310ExtracellularSequence analysis8
Transmembranei1311 – 1331HelicalSequence analysisAdd BLAST21
Topological domaini1332 – 1347CytoplasmicSequence analysisAdd BLAST16

Keywords - Cellular componenti

Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003083301 – 1347Protein dispatched homolog 3Add BLAST1347

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi157N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi976N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A3KFU9

PRoteomics IDEntifications database

More...
PRIDEi
A3KFU9

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A3KFU9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in brain, retina, testis and thymus (PubMed:19179482).1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Down-regulated by thyroid hormone T3 (PubMed:19179482).1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000038490

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini412 – 570SSDPROSITE-ProRule annotationAdd BLAST159

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SSD (sterol-sensing) domain is necessary for the increase in cellular cholesterol uptake.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the patched family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410INZQ Eukaryota
ENOG410YJQF LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115763

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A3KFU9

Database of Orthologous Groups

More...
OrthoDBi
56949at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A3KFU9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02460 Patched, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50156 SSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: A3KFU9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSEDDPLLQ DVWLEEEQPE DEACRGIPGP GLQSGAQGCW RRWTLPSRPP
60 70 80 90 100
TLGFWSTLGW AFTNPCCAGL VLFLGCSIPM VLSAFMFLYY PPLDIDISYN
110 120 130 140 150
AFEIRNHEAS QRFDALALAL KSQFGSWGRN RRDLADFTSE TLQRLISEQL
160 170 180 190 200
QQLHLGNHSR PASRAPRSAP RDTVATQTSA ANSSERRRRE APSPEGQVTN
210 220 230 240 250
QSRARRGASR WDYSRTYVSA NTQTHAHWRI ELIFLARGDA ERNIFTSERL
260 270 280 290 300
VTIHEIERKI MDHPGFREFC WKPHEVLKDL PLGSYSYCSP PSSLMTYFFP
310 320 330 340 350
TERGGKIYYD GMGQDLADIR GSLELAMTHP EFYWYVDEGL SVDNLKSSLL
360 370 380 390 400
RSEILFGAPL PNYYSVDDRW EEQRAKFQSF VVTYVAMLAK QSTSKVQVLY
410 420 430 440 450
GGTDLFDYEV RRTFNNDMLL AFISSSCIAA LVYILTSCSV FLSFFGIASI
460 470 480 490 500
GLSCLVALFL YHVVFGIQYL GILNGVAAFV IVGIGVDDVF VFINTYRQAT
510 520 530 540 550
HLEDPQLRMI HTIQTAGKAT FFTSLTTAAA YAANVFSQIP AVHDFGLFMS
560 570 580 590 600
LIVTCCWLAV LFTMPAALGL WSLYMAPLES SCQNSCHQKC GRKSSLHFPG
610 620 630 640 650
DLFTAPERAG GGPAQGPLPY LDDDIPLLNV EDEPASLELG DVSLVSVHCE
660 670 680 690 700
GLQPTPDANS RGQLLAQLQE LLHHWVLWAA VKSRWVIVGL FASILILSLV
710 720 730 740 750
FASRLRPASR APLLFRPDTN IQVLLDLKYN LSAEGISCIT CSGLFQEKPH
760 770 780 790 800
SLQNNVRTSL EKKKRGSGVS WASRTETTAQ ESMSTVYISK VKSKGHPAVY
810 820 830 840 850
RLSLNASLPA PWQAVSPGDG EVPSFQVYRA PFGDFTKKLT ACMSTVGLLQ
860 870 880 890 900
AASPSRKWMV TALACDARRG WKFDFSFYVA TKEQQHTRKL YFAQSHKPPF
910 920 930 940 950
HGRLCVAPPG CLLSSSPDGP TKGFFYVPSD KVPKARISAT FGFNPCVNTG
960 970 980 990 1000
CGKPAVRPLV DTGAMVFVVF GIIGLNRTQQ MDNHVIGDPG SVIYDSSFDL
1010 1020 1030 1040 1050
FKEIGHLCRL CKAIAGNSEL VKPGGAQCLP SGYSISSFLQ MLHPECKELP
1060 1070 1080 1090 1100
EPNLLPGQLS HGAVGVKEGR VQWISMAFES TTYKGKSSFQ TYSDYLRWES
1110 1120 1130 1140 1150
FLRQQLQTFP EGSALHRGFQ TCEHWKQIFM EIIGVQSALY GLVLSLLICV
1160 1170 1180 1190 1200
AAVAVFTTHV LLLLPVLLSI LGIVCLVVTI MYWSGWEMGA VEAISLSILV
1210 1220 1230 1240 1250
GSSVDYCVHL VEGYLLAGEN LPPQLSQDPS SQRQWRTLEA VRHVGVAIVS
1260 1270 1280 1290 1300
SALTTVIATV PLFFCIIAPF AKFGKIVALN TGVSILYTLT VSTALLGIMA
1310 1320 1330 1340
PGSFTRTRTS FLKALGAVLL AGALGLGACL VLLRSGYKIP LPSGATL
Length:1,347
Mass (Da):148,446
Last modified:April 3, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55EBCFB73F9659E0
GO
Isoform 2 (identifier: A3KFU9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     827-839: VYRAPFGDFTKKL → GCFRRRAPPASGW
     840-1347: Missing.

Note: No experimental confirmation available.
Show »
Length:839
Mass (Da):93,488
Checksum:i36C8FEA57AC7F9ED
GO
Isoform 3 (identifier: A3KFU9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     827-1347: Missing.

Note: No experimental confirmation available.
Show »
Length:826
Mass (Da):92,045
Checksum:iA2B1F04BF4684EBE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QL24E9QL24_MOUSE
Protein dispatched homolog 3
Disp3 Ptchd2
1,347Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti27I → V in BAF32145 (Ref. 1) Curated1
Sequence conflicti193S → P in BAF32145 (Ref. 1) Curated1
Sequence conflicti193S → P in BAD32430 (PubMed:15368895).Curated1
Sequence conflicti775T → P in BAF32145 (Ref. 1) Curated1
Sequence conflicti775T → P in BAD32430 (PubMed:15368895).Curated1
Sequence conflicti951C → W in BAD32430 (PubMed:15368895).Curated1
Sequence conflicti1018S → L in BAF32145 (Ref. 1) Curated1
Sequence conflicti1018S → L in BAD32430 (PubMed:15368895).Curated1
Sequence conflicti1225 – 1227LSQ → QAE in BAF32145 (Ref. 1) Curated3
Sequence conflicti1225 – 1227LSQ → QAE in BAD32430 (PubMed:15368895).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_028967827 – 1347Missing in isoform 3. 1 PublicationAdd BLAST521
Alternative sequenceiVSP_028968827 – 839VYRAP…FTKKL → GCFRRRAPPASGW in isoform 2. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_028969840 – 1347Missing in isoform 2. 1 PublicationAdd BLAST508

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB235901 mRNA Translation: BAF32145.1
AL606919 Genomic DNA No translation available.
AL645605 Genomic DNA No translation available.
BC070441 mRNA Translation: AAH70441.1
BC072569 mRNA Translation: AAH72569.1
AK173152 mRNA Translation: BAD32430.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS38966.1 [A3KFU9-1]

NCBI Reference Sequences

More...
RefSeqi
XP_011248557.1, XM_011250255.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
242748

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB235901 mRNA Translation: BAF32145.1
AL606919 Genomic DNA No translation available.
AL645605 Genomic DNA No translation available.
BC070441 mRNA Translation: AAH70441.1
BC072569 mRNA Translation: AAH72569.1
AK173152 mRNA Translation: BAD32430.1
CCDSiCCDS38966.1 [A3KFU9-1]
RefSeqiXP_011248557.1, XM_011250255.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038490

PTM databases

PhosphoSitePlusiA3KFU9

Proteomic databases

PaxDbiA3KFU9
PRIDEiA3KFU9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi242748

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57540
MGIiMGI:2444403 Disp3

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiENOG410INZQ Eukaryota
ENOG410YJQF LUCA
HOGENOMiHOG000115763
InParanoidiA3KFU9
OrthoDBi56949at2759
PhylomeDBiA3KFU9

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A3KFU9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD
PfamiView protein in Pfam
PF02460 Patched, 2 hits
PROSITEiView protein in PROSITE
PS50156 SSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDISP3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A3KFU9
Secondary accession number(s): Q0EEE3
, Q69ZL6, Q6GQX3, Q6NS63
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: April 3, 2007
Last modified: May 8, 2019
This is version 60 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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