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UniProtKB - A3FQN0 (A3FQN0_CRYPI)
Protein
Protein kinase domain-containing protein
Gene
cgd4_240
Organism
Cryptosporidium parvum (strain Iowa II)
Status
Functioni
Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 88 | ATPPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- protein serine/threonine kinase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein kinase domain-containing proteinInterPro annotation |
Gene namesi | ORF Names:cgd4_240Imported |
Organismi | Cryptosporidium parvum (strain Iowa II)Imported |
Taxonomic identifieri | 353152 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Conoidasida › Coccidia › Eucoccidiorida › Eimeriorina › Cryptosporidiidae › Cryptosporidium › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | CryptoDB:cgd4_240 |
PTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 253 | Combined sources |
Structurei
3D structure databases
SMRi | A3FQN0 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | A3FQN0 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 59 – 375 | Protein kinaseInterPro annotationAdd BLAST | 317 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 124 – 147 | DisorderedSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.ARBA annotation
Phylogenomic databases
InParanoidi | A3FQN0 |
OMAi | MQYTQCK |
Family and domain databases
CDDi | cd14137, STKc_GSK3, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS IPR039192, STKc_GSK3 |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
A3FQN0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNVNVQLSR KQQLLERGCN EMIEEKTNLT NLNHNVTLSS GLSTTATSST
60 70 80 90 100
NLETSSKKYS LGKTLGTGSF GIVCEVFDIE SGKRFALKKV LQDPRYKNRE
110 120 130 140 150
LDIMKVLDHV NIIKLVDYFY TTGDEEPKPP QPPDDHNKLG GKNNGVNNHH
160 170 180 190 200
KSVIVNPSQN KYLNVIMEYV PDTLHKVLKS FIRSGRSIPM NLISIYIYQL
210 220 230 240 250
FRAVGFIHSL GICHRDIKPQ NLLVNSKDNT LKLCDFGSAK KLIPSEPSVA
260 270 280 290 300
YICSRFYRAP ELMLGATEYT PSIDLWSIGC VFGELILGKP LFSGETSIDQ
310 320 330 340 350
LVRIIQIMGT PTKEQMIRMN PHYTEVRFPT LKAKDWRKIL PEGTPSLAID
360 370 380 390 400
LLEQILRYEP DLRINPYEAM AHPFFDHLRN SYESEVKNNS NFPHGVNQNI
410 420 430
PQLFNFSPYE LSIIPGNVLN RILPKNFSPN YKH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEE01000009 Genomic DNA Translation: EAZ51236.1 |
RefSeqi | XP_001388048.1, XM_001388011.1 |
Genome annotation databases
EnsemblProtistsi | EAZ51236; EAZ51236; cgd4_240 |
GeneIDi | 3372632 |
KEGGi | cpv:cgd4_240 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEE01000009 Genomic DNA Translation: EAZ51236.1 |
RefSeqi | XP_001388048.1, XM_001388011.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3EB0 | X-ray | 2.65 | A/C | 52-433 | [»] | |
SMRi | A3FQN0 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 353152.A3FQN0 |
Genome annotation databases
EnsemblProtistsi | EAZ51236; EAZ51236; cgd4_240 |
GeneIDi | 3372632 |
KEGGi | cpv:cgd4_240 |
Organism-specific databases
VEuPathDBi | CryptoDB:cgd4_240 |
Phylogenomic databases
InParanoidi | A3FQN0 |
OMAi | MQYTQCK |
Miscellaneous databases
EvolutionaryTracei | A3FQN0 |
Family and domain databases
CDDi | cd14137, STKc_GSK3, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS IPR039192, STKc_GSK3 |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A3FQN0_CRYPI | |
Accessioni | A3FQN0Primary (citable) accession number: A3FQN0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 3, 2007 |
Last sequence update: | April 3, 2007 | |
Last modified: | January 19, 2022 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |