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Entry version 115 (25 May 2022)
Sequence version 1 (20 Mar 2007)
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Protein

Phospholipid-transporting ATPase FetA

Gene

Atp8b5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in phospholid transport across membranes and in acrosome formation.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2). EC:7.6.2.1

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei4164-aspartylphosphate intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi838MagnesiumBy similarity1
Metal bindingi842MagnesiumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processLipid transport, Transport
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phospholipid-transporting ATPase FetA (EC:7.6.2.1)
Alternative name(s):
ATPase class I type 8B member 2-like protein
ATPase class I type 8B member 5
Flippase expressed in testis A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Atp8b5
Synonyms:Feta
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444287, Atp8b5

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000028457

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei299 – 319HelicalSequence analysisAdd BLAST21
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21
Transmembranei904 – 924HelicalSequence analysisAdd BLAST21
Transmembranei927 – 947HelicalSequence analysisAdd BLAST21
Transmembranei981 – 1001HelicalSequence analysisAdd BLAST21
Transmembranei1014 – 1034HelicalSequence analysisAdd BLAST21
Transmembranei1049 – 1069HelicalSequence analysisAdd BLAST21
Transmembranei1090 – 1110HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003219551 – 1183Phospholipid-transporting ATPase FetAAdd BLAST1183

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A3FIN4

PRoteomics IDEntifications database

More...
PRIDEi
A3FIN4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
265156 [A3FIN4-1]
265157 [A3FIN4-2]
265158 [A3FIN4-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A3FIN4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A3FIN4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in testis.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Not detected in testis until 18 days postpartum. At 22 days postpartum, levels increase and remain constant during adulthood. During spermatogenesis, expressed from pachytene spermatocytes to mature sperm.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028457, Expressed in testis and 68 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A3FIN4, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000103575

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A3FIN4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
A3FIN4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A3FIN4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0206, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161917

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000846_3_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A3FIN4

Identification of Orthologs from Complete Genome Data

More...
OMAi
NDMERIM

Database of Orthologous Groups

More...
OrthoDBi
587717at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A3FIN4

TreeFam database of animal gene trees

More...
TreeFami
TF300654

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1110.10, 1 hit
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR030350, FetA
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006539, P-type_ATPase_IV
IPR032631, P-type_ATPase_N
IPR001757, P_typ_ATPase
IPR032630, P_typ_ATPase_c
IPR044492, P_typ_ATPase_HD_dom

The PANTHER Classification System

More...
PANTHERi
PTHR24092:SF52, PTHR24092:SF52, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16212, PhoLip_ATPase_C, 1 hit
PF16209, PhoLip_ATPase_N, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDF00027, p-type_atpase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01652, ATPase-Plipid, 1 hit
TIGR01494, ATPase_P-type, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A3FIN4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKYVKAFVSE ISWDCSWYCS AMQERRNEDR QKEEEERILQ ANNRRFNSLF
60 70 80 90 100
EYPDNSIKTS KYGFFNFLPM NLFEQFQRLA NAYFLILLFL QLVPQISSLA
110 120 130 140 150
WYTTVIPLIV VLSITGVKDA IDDVKRHRSD QQINNRSVSI LVNGRVEEIK
160 170 180 190 200
WRNVQVGDII KLENNHPVTA DMLLLSSSEP YGLTYIETAD LDGETNLKVK
210 220 230 240 250
QAISVTSAME DNLELLSSFN GEVRCDPPNN KLDKFSGTLS YLGNTYLLNH
260 270 280 290 300
ERLLLRGCVI RNTDWCYGLV VYTGQDTKLM QNSGRSTFKR THIDHLMNVL
310 320 330 340 350
VVWIFMFLGG MCFLLSIGHG IWENSRGYYF QAFLPWKHYI TSSATSSALI
360 370 380 390 400
FWSYFIVLNT MVPISLYVSV EIIRLGNSYY INWDRKMFYA PKNMPAQART
410 420 430 440 450
TTLNEELGQV QYVFSDKTGT LTENVMIFNK CSINGKTYGY SYDDNGEYVP
460 470 480 490 500
KSPKDKVDFS YNHLADPKFS FYDKTLVEAV KSEDPLVYLF FLCLSLCHTV
510 520 530 540 550
MSEEKVEGEL VYQAQSPDEG ALVTATRNFG FVFCSRTPET ITVIEMGKIR
560 570 580 590 600
VYRLLAILDF SNERKRMSVI VRTPEDRVML FCKGADTIIY ELLHPSCASL
610 620 630 640 650
SEVTMDHLDD FASEGLRTLM VAYRELDKAY FQTWIKKHGE AWLTLENRER
660 670 680 690 700
KLALVYEEIE RDLMLLGATA IEDKLQRGVP ETIVTLSKAK IKIWVLTGDK
710 720 730 740 750
QETAVNIAYS CRIFKDEMDG VFMVEGTDRE TVLEELRTAR KKMKPESLLE
760 770 780 790 800
SDPINMYLAR KPKMPFKSLD EVANGNYGLV ISGYSLAYAL EGSLEFELLR
810 820 830 840 850
TACMCKGVVC CRMTPLQKAQ VVDLVKRYKK VVTLAIGDGA NDISMIKAAH
860 870 880 890 900
IGVGISNQEG MQATLSSDFS FCQFHFLQRL LLVHGRLSYN RMCKFLSYFF
910 920 930 940 950
YKNFAFTLVH FWYAFFNGFS AQTVYDIWFI TFYNLIYTSL PVLGLSLFEK
960 970 980 990 1000
DVNETWSLCY PELYEPGQHN LYFNKKEFVK CLLHGIYNSF VLFFVPMGTV
1010 1020 1030 1040 1050
FNSERNDGKD ISDFQSFSLL VQTTLIGVMT MQIALRTTSW TMINHTFTWG
1060 1070 1080 1090 1100
SLGLYFCILI LLCSDGLCLR YPSIFNFLGV ARNSLSQPQI WLCLILSTIL
1110 1120 1130 1140 1150
CMIPLIGYNF LRPLLWPINA DKVLNRIHFC LKHPIPTQVQ TKIKHPSLRR
1160 1170 1180
SAYAFSHKQG FGALITSGKT LKSSALAKSK RFL
Length:1,183
Mass (Da):135,899
Last modified:March 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFB70541AE6A0714
GO
Isoform 2 (identifier: A3FIN4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     304-305: IF → VS
     306-1183: Missing.

Show »
Length:305
Mass (Da):35,259
Checksum:i015F7667BA93C2DD
GO
Isoform 3 (identifier: A3FIN4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     454-460: KDKVDFS → VSNYSFL
     461-1183: Missing.

Show »
Length:460
Mass (Da):53,163
Checksum:iBFBE91122F61C688
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RG77D6RG77_MOUSE
Phospholipid-transporting ATPase Fe...
Atp8b5
47Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RHC0D6RHC0_MOUSE
Phospholipid-transporting ATPase Fe...
Atp8b5
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2 – 33KYVKA…DRQKE → GSNGASSHRTSTLLTGQPSQ HPRLVSEQIPQQ in CAM16528 (PubMed:19468303).CuratedAdd BLAST32

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_031844304 – 305IF → VS in isoform 2. 1 Publication2
Alternative sequenceiVSP_031845306 – 1183Missing in isoform 2. 1 PublicationAdd BLAST878
Alternative sequenceiVSP_031846454 – 460KDKVDFS → VSNYSFL in isoform 3. 1 Publication7
Alternative sequenceiVSP_031847461 – 1183Missing in isoform 3. 1 PublicationAdd BLAST723

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EF377342 mRNA Translation: ABN48718.1
AK076708 mRNA Translation: BAC36451.1
AK078567 mRNA Translation: BAC37336.1
AL732504 Genomic DNA Translation: CAM16526.1
AL732504 Genomic DNA Translation: CAM16528.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18091.2 [A3FIN4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_796169.2, NM_177195.3 [A3FIN4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000102953; ENSMUSP00000100018; ENSMUSG00000028457 [A3FIN4-2]
ENSMUST00000107942; ENSMUSP00000103575; ENSMUSG00000028457 [A3FIN4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
320571

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:320571

UCSC genome browser

More...
UCSCi
uc008spj.1, mouse [A3FIN4-2]
uc008spk.1, mouse [A3FIN4-3]
uc008spl.1, mouse [A3FIN4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF377342 mRNA Translation: ABN48718.1
AK076708 mRNA Translation: BAC36451.1
AK078567 mRNA Translation: BAC37336.1
AL732504 Genomic DNA Translation: CAM16526.1
AL732504 Genomic DNA Translation: CAM16528.2
CCDSiCCDS18091.2 [A3FIN4-1]
RefSeqiNP_796169.2, NM_177195.3 [A3FIN4-1]

3D structure databases

AlphaFoldDBiA3FIN4
SMRiA3FIN4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103575

PTM databases

iPTMnetiA3FIN4
PhosphoSitePlusiA3FIN4

Proteomic databases

PaxDbiA3FIN4
PRIDEiA3FIN4
ProteomicsDBi265156 [A3FIN4-1]
265157 [A3FIN4-2]
265158 [A3FIN4-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
320571

Genome annotation databases

EnsembliENSMUST00000102953; ENSMUSP00000100018; ENSMUSG00000028457 [A3FIN4-2]
ENSMUST00000107942; ENSMUSP00000103575; ENSMUSG00000028457 [A3FIN4-1]
GeneIDi320571
KEGGimmu:320571
UCSCiuc008spj.1, mouse [A3FIN4-2]
uc008spk.1, mouse [A3FIN4-3]
uc008spl.1, mouse [A3FIN4-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
320571
MGIiMGI:2444287, Atp8b5
VEuPathDBiHostDB:ENSMUSG00000028457

Phylogenomic databases

eggNOGiKOG0206, Eukaryota
GeneTreeiENSGT00940000161917
HOGENOMiCLU_000846_3_2_1
InParanoidiA3FIN4
OMAiNDMERIM
OrthoDBi587717at2759
PhylomeDBiA3FIN4
TreeFamiTF300654

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
320571, 1 hit in 73 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Atp8b5, mouse

Protein Ontology

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PROi
PR:A3FIN4
RNActiA3FIN4, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000028457, Expressed in testis and 68 other tissues
ExpressionAtlasiA3FIN4, baseline and differential

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR030350, FetA
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006539, P-type_ATPase_IV
IPR032631, P-type_ATPase_N
IPR001757, P_typ_ATPase
IPR032630, P_typ_ATPase_c
IPR044492, P_typ_ATPase_HD_dom
PANTHERiPTHR24092:SF52, PTHR24092:SF52, 1 hit
PfamiView protein in Pfam
PF16212, PhoLip_ATPase_C, 1 hit
PF16209, PhoLip_ATPase_N, 1 hit
SFLDiSFLDF00027, p-type_atpase, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit
TIGRFAMsiTIGR01652, ATPase-Plipid, 1 hit
TIGR01494, ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAT8B5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A3FIN4
Secondary accession number(s): A2AIL8, Q8BVE9, Q8BVS7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 20, 2007
Last modified: May 25, 2022
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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