UniProtKB - A3EXD2 (NS3B_BCHK5)
Protein
Non-structural protein 3b
Gene
3b
Organism
Bat coronavirus HKU5 (BtCoV) (BtCoV/HKU5/2004)
Status
Functioni
Induces host cell G0/G1 arrest and apoptosis.By similarity
GO - Molecular functioni
- RNA binding Source: UniProtKB-KW
GO - Biological processi
- modulation by virus of host apoptotic process Source: UniProtKB-KW
- modulation by virus of host G0/G1 transition checkpoint Source: UniProtKB-KW
Keywordsi
Names & Taxonomyi
Protein namesi | Recommended name: Non-structural protein 3bShort name: ns3b Alternative name(s): Accessory protein 3b |
Gene namesi | ORF Names:3b |
Organismi | Bat coronavirus HKU5 (BtCoV) (BtCoV/HKU5/2004) |
Taxonomic identifieri | 694008 [NCBI] |
Taxonomic lineagei | Viruses › Riboviria › Orthornavirae › Pisuviricota › Pisoniviricetes › Nidovirales › Cornidovirineae › Coronaviridae › Orthocoronavirinae › Betacoronavirus › Merbecovirus |
Virus hosti | Pipistrellus abramus (Japanese pipistrelle) (Pipistrellus javanicus abramus) [TaxID: 105295] |
Proteomesi |
|
Subcellular locationi
- host nucleolus By similarity
- Host mitochondrion By similarity
GO - Cellular componenti
- host cell mitochondrion Source: UniProtKB-SubCell
- host cell nucleolus Source: UniProtKB-SubCell
Keywords - Cellular componenti
Host mitochondrion, Host nucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000290266 | 1 – 119 | Non-structural protein 3bAdd BLAST | 119 |
Interactioni
Subunit structurei
Interacts with host RUNX1 isoform b.
By similarityFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 79 | DRBMAdd BLAST | 77 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 114 – 117 | Poly-Ser | 4 |
i Sequence
Sequence statusi: Complete.
A3EXD2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDYVSLLNQV WQKQVNSSQE GTLAPVRPTY AYRPVQGNLQ CPIKWRCIYT
60 70 80 90 100
FAGYTGTATE PTKVLAKQEA ARKVCLRLQE YGRLDGFGLR LRYSTAFEHN
110
RYDASKSYFY TQTSSSSHE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF065509 Genomic RNA Translation: ABN10877.1 |
RefSeqi | YP_001039964.1, NC_009020.1 |
Genome annotation databases
GeneIDi | 4836005 |
KEGGi | vg:4836005 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EF065509 Genomic RNA Translation: ABN10877.1 |
RefSeqi | YP_001039964.1, NC_009020.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 4836005 |
KEGGi | vg:4836005 |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | NS3B_BCHK5 | |
Accessioni | A3EXD2Primary (citable) accession number: A3EXD2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 12, 2007 |
Last sequence update: | March 20, 2007 | |
Last modified: | December 2, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |