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Entry version 61 (12 Aug 2020)
Sequence version 1 (20 Mar 2007)
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Protein

Mutator family transposase

Gene

Cthe_0148

Organism
Hungateiclostridium thermocellum (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the transposition of the insertion element.UniRule annotationARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processDNA recombinationUniRule annotationARBA annotation, TranspositionUniRule annotationARBA annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
CTHE203119:G1G86-1248-MONOMER
CTHE203119:G1G86-154-MONOMER
CTHE203119:G1G86-1956-MONOMER
CTHE203119:G1G86-3194-MONOMER
CTHE203119:G1G86-373-MONOMER
CTHE203119:G1G86-390-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mutator family transposaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Cthe_0148Imported, Cthe_0356Imported, Cthe_0371Imported, Cthe_1193Imported, Cthe_1874Imported, Cthe_3051Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHungateiclostridium thermocellum (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri203119 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesHungateiclostridiaceaeHungateiclostridium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002145 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the transposase mutator family.UniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG3328, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_036805_2_0_9

KEGG Orthology (KO)

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KOi
K07493

Identification of Orthologs from Complete Genome Data

More...
OMAi
FEASEGM

Database of Orthologous Groups

More...
OrthoDBi
792870at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001207, Transposase_mutator

The PANTHER Classification System

More...
PANTHERi
PTHR33217, PTHR33217, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00872, Transposase_mut, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01007, TRANSPOSASE_MUTATOR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A3DBR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARKRIITPE KKELIRNLIS EYNITSAKDL QEALKDLLGD TIQNMLEAEL
60 70 80 90 100
DEHLGYEKYE STEEAKSNYR NGYTSKTLKS SVGQVEIDIP RDRNAEFEPK
110 120 130 140 150
IVPRYKRDIS EIENKIIAMY ARGMSTREIN EQIQEIYGFE VSAEMVSKIT
160 170 180 190 200
DKILPEIEEW QKRPLGEVYP IVFIDAIHFS VKNDGIVGKK AVYIVLAIDI
210 220 230 240 250
EGQKDVIGIY VGENESSKFW LSVLNDLKNR GVKDILILCA DALSGIKDAI
260 270 280 290 300
NAAFPNTEYQ RCIVHQIRNT LKYVSDKDRK EFARDLKRIY TAPNEKAGYD
310 320 330 340 350
QMLEVSEKWE KKYPAAMKSW KSNWDVICPF FKYSEELRKI MYTTNTIESL
360 370 380 390 400
NSSYRRINKS RTVFPGDQSL LKSIYLATVK ITSKWTMRYK NWGLILGQLQ

IMFEGRI
Length:407
Mass (Da):47,217
Last modified:March 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i57A64F2B990C9143
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CP000568 Genomic DNA Translation: ABN51389.1
CP000568 Genomic DNA Translation: ABN51594.1
CP000568 Genomic DNA Translation: ABN51609.1
CP000568 Genomic DNA Translation: ABN52425.1
CP000568 Genomic DNA Translation: ABN53095.1
CP000568 Genomic DNA Translation: ABN54247.1

NCBI Reference Sequences

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RefSeqi
WP_003512622.1, NC_009012.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABN51389; ABN51389; Cthe_0148
ABN51594; ABN51594; Cthe_0356
ABN51609; ABN51609; Cthe_0371
ABN52425; ABN52425; Cthe_1193
ABN53095; ABN53095; Cthe_1874
ABN54247; ABN54247; Cthe_3051

Database of genes from NCBI RefSeq genomes

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GeneIDi
35805618

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cth:Cthe_0148
cth:Cthe_0356
cth:Cthe_0371
cth:Cthe_1193
cth:Cthe_1874
cth:Cthe_3051

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000568 Genomic DNA Translation: ABN51389.1
CP000568 Genomic DNA Translation: ABN51594.1
CP000568 Genomic DNA Translation: ABN51609.1
CP000568 Genomic DNA Translation: ABN52425.1
CP000568 Genomic DNA Translation: ABN53095.1
CP000568 Genomic DNA Translation: ABN54247.1
RefSeqiWP_003512622.1, NC_009012.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiABN51389; ABN51389; Cthe_0148
ABN51594; ABN51594; Cthe_0356
ABN51609; ABN51609; Cthe_0371
ABN52425; ABN52425; Cthe_1193
ABN53095; ABN53095; Cthe_1874
ABN54247; ABN54247; Cthe_3051
GeneIDi35805618
KEGGicth:Cthe_0148
cth:Cthe_0356
cth:Cthe_0371
cth:Cthe_1193
cth:Cthe_1874
cth:Cthe_3051

Phylogenomic databases

eggNOGiCOG3328, Bacteria
HOGENOMiCLU_036805_2_0_9
KOiK07493
OMAiFEASEGM
OrthoDBi792870at2

Enzyme and pathway databases

BioCyciCTHE203119:G1G86-1248-MONOMER
CTHE203119:G1G86-154-MONOMER
CTHE203119:G1G86-1956-MONOMER
CTHE203119:G1G86-3194-MONOMER
CTHE203119:G1G86-373-MONOMER
CTHE203119:G1G86-390-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR001207, Transposase_mutator
PANTHERiPTHR33217, PTHR33217, 1 hit
PfamiView protein in Pfam
PF00872, Transposase_mut, 1 hit
PROSITEiView protein in PROSITE
PS01007, TRANSPOSASE_MUTATOR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA3DBR0_HUNT2
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A3DBR0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported, Transposable elementUniRule annotationARBA annotation
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