Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei160GTPUniRule annotation1
Binding sitei163GTPUniRule annotation1
Binding sitei206GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi42 – 46GTPUniRule annotation5
Nucleotide bindingi129 – 131GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR368407:G1G85-1447-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Memar_1449Imported
OrganismiMethanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)Imported
Taxonomic identifieri368407 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanomicrobiaceaeMethanoculleus
Proteomesi
  • UP000002146 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi368407.Memar_1449

Structurei

3D structure databases

ProteinModelPortaliA3CVH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 224TubulinInterPro annotationAdd BLAST191
Domaini226 – 343Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201 Archaea
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiIMNQGGV
OrthoDBiPOG093Z0942

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit

Sequencei

Sequence statusi: Complete.

A3CVH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTIINEALK HAEREKYLKT DMVDGEDDII GQPRIVIVGC GGAGNNTVNR
60 70 80 90 100
LYHMQVSGAE TIAINTDKQH LDMIQADKRV LVGKSLTKGL GAGGFPDVGR
110 120 130 140 150
RAAEMARPTL ESLLCDADLV FITAGMGGGT GTGTAPVVAQ IAKEQGAIVV
160 170 180 190 200
GMVSYPFQVE KARLLRAEEG LEQLSASADS VIVLDNNRLI KYVPNLPLGQ
210 220 230 240 250
AFSVMDQLIA ETVKGISETI TEPSLINIDY ADVRAIMSKG GVAVMLVGES
260 270 280 290 300
KQQNKAESVV HECLNHPLLD IDYRGATGSL IHITGGNDLT LQDAEEIASS
310 320 330 340 350
LTYELDPHAD VIWGARVNSD YEGRVRVMAV MTGVKSAQIL GSHRTYEQVA
360 370
QRSSAPAGRR IAGDSPSGHL IDFL
Length:374
Mass (Da):39,973
Last modified:March 20, 2007 - v1
Checksum:i65A4AA1F270A81EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000562 Genomic DNA Translation: ABN57378.1
RefSeqiWP_011844289.1, NC_009051.1

Genome annotation databases

EnsemblBacteriaiABN57378; ABN57378; Memar_1449
GeneIDi4847896
KEGGimem:Memar_1449

Similar proteinsi

Entry informationi

Entry nameiA3CVH8_METMJ
AccessioniPrimary (citable) accession number: A3CVH8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: July 18, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health