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UniProtKB - A3A4E0 (CDT4_ORYSJ)
Protein
Protein CADMIUM TOLERANCE 4
Gene
CDT4
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Confers resistance to heavy metal ions (e.g. aluminium (Al)) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation.
1 PublicationKeywordsi
Biological process | Stress response |
Ligand | Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein CADMIUM TOLERANCE 41 PublicationShort name: Cd tolerant 41 Publication Short name: OsCDT41 Publication |
Gene namesi | Name:CDT41 Publication Ordered Locus Names:Os02g0208500Imported ORF Names:OsJ_05841Imported, OSNPB_020208500Imported |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Single-pass membrane protein Sequence analysis
Cell wall
- cell wall By similarity
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 26 – 42 | HelicalSequence analysisAdd BLAST | 17 |
Keywords - Cellular componenti
Cell membrane, Cell wall, Membrane, SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000454818 | 1 – 60 | Protein CADMIUM TOLERANCE 4Add BLAST | 60 |
Expressioni
Tissue specificityi
Mainly expressed in shoots, and, to a lower extent, in roots.1 Publication
Inductioni
Down-regulated in root tissues but up-regulated in shoot tissues in response to cadmium (CdCl2).1 Publication
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the CYSTM1 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502R5EE, Eukaryota |
HOGENOMi | CLU_156676_2_0_1 |
OMAi | HVRRRHE |
Family and domain databases
InterProi | View protein in InterPro IPR028144, CYSTM_dom |
Pfami | View protein in Pfam PF12734, CYSTM, 1 hit |
i Sequence
Sequence statusi: Complete.
A3A4E0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDEPSQGGDQ KLSAMEHVKK RHEEKGFLYA CLFMLCCCFC CYETCEHCLE
60
CFCCCCKKDN
Sequence cautioni
The sequence BAG87062 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP008208 Genomic DNA Translation: BAH91578.1 AP014958 Genomic DNA Translation: BAS77575.1 CM000139 Genomic DNA Translation: EAZ22179.1 AK059641 mRNA Translation: BAG87062.1 Frameshift. |
Genome annotation databases
EnsemblPlantsi | Os02t0208500-01; Os02t0208500-01; Os02g0208500 |
Gramenei | Os02t0208500-01; Os02t0208500-01; Os02g0208500 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP008208 Genomic DNA Translation: BAH91578.1 AP014958 Genomic DNA Translation: BAS77575.1 CM000139 Genomic DNA Translation: EAZ22179.1 AK059641 mRNA Translation: BAG87062.1 Frameshift. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 4530.OS02T0208500-01 |
Genome annotation databases
EnsemblPlantsi | Os02t0208500-01; Os02t0208500-01; Os02g0208500 |
Gramenei | Os02t0208500-01; Os02t0208500-01; Os02g0208500 |
Phylogenomic databases
eggNOGi | ENOG502R5EE, Eukaryota |
HOGENOMi | CLU_156676_2_0_1 |
OMAi | HVRRRHE |
Family and domain databases
InterProi | View protein in InterPro IPR028144, CYSTM_dom |
Pfami | View protein in Pfam PF12734, CYSTM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CDT4_ORYSJ | |
Accessioni | A3A4E0Primary (citable) accession number: A3A4E0 Secondary accession number(s): A0A0P0VG95, B7E3W5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 23, 2022 |
Last sequence update: | March 20, 2007 | |
Last modified: | February 23, 2022 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families