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Entry version 92 (17 Jun 2020)
Sequence version 1 (20 Mar 2007)
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Protein
Submitted name:

NBS-LRR disease resistance protein

Gene

Pit

Organism
Oryza sativa subsp. japonica (Rice)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPlant defenseSAAS annotation
LigandNucleotide-bindingSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
NBS-LRR disease resistance proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PitImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 88Rx_NInterPro annotationAdd BLAST77
Domaini185 – 386NB-ARCInterPro annotationAdd BLAST202

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili34 – 54Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4658 Eukaryota
COG4886 LUCA

Database of Orthologous Groups

More...
OrthoDBi
127153at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14798 RX-CC_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032675 LRR_dom_sf
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR038005 RX-like_CC
IPR041118 Rx_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00931 NB-ARC, 1 hit
PF18052 Rx_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2ZP99-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTVLDALAW KFLEKLGQLI EDEVIMTLSV KRGIESLKKN LEFFNAVHED
60 70 80 90 100
AEALAMEDPG IDSWWKNMRD VMFDVDDIVD LFMVHSQKLL LPPRPVCCNQ
110 120 130 140 150
PLFSSFAKFS FDHMIAKRID NINEKFEEIK MNKEMFGLER TNGQQIQITI
160 170 180 190 200
VDRSQTSPVD ELEVVGEDIR RAIDDIVKMI VSSNYNESRS TVFGIQGMGG
210 220 230 240 250
IGKTTLAQKI YNEQRIREKF QVHIWLCISQ NYTETSLLKQ AIRMAGGICD
260 270 280 290 300
QLETKTELLP LLVDTIRGKS VFLVLDDVWK SDVWIDLLRL PFLRGLNSHI
310 320 330 340 350
LVTSRNLDVL VEMHATYTHK VNKMNDCDGL ELLMKMSLGP YEQSREFSGV
360 370 380 390 400
GYQIVKKCDG LPLAIKVVAG VLSTKRTRAE WESIRDSKWS IHGLPRELGG
410 420 430 440 450
PLYLSYSNLP PELKQCFLWC ALLPSNFVIR RDAVAYWWVA EGFVTEVHGY
460 470 480 490 500
SIHEVAEEYY HELIRRNLLQ PRPEFVDKGE STMHDLLRSL GQFLTKDHSI
510 520 530 540 550
FMNMEYSKAL PNLRHLCISN DVEEIPAIEK QKCLRSLLVF DNKNFMKINK
560 570 580 590 600
DIFRELKHIR VLVLSGTSIQ IIPESVGNFL LLRLLDLSYT KIQKLPESIG
610 620 630 640 650
KLTSLEYLSL HGCIHLDSLP DSLMRLSNIS FLELEQTAID HVPKGVAKLQ
660 670 680 690 700
QLYNLRGVFD SGTGFRLDEL QCLSNIQRLR IVKLEKAAPG GSFVLKNCLH
710 720 730 740 750
LRELWLGCTI GGHDKTYYQT NEIERIQQVY ELLIPSPSLL YIFLVGFPGV
760 770 780 790 800
RFPDWLCSEP ERKMPNLGHM HLNDCTSCSV LPPAGQMPEL LVFKIKGADA
810 820 830 840 850
IVNMGAELLG KGVNSAKHIT IFPKLELLLI TNMSNLESWS LNTWNLCGKS
860 870 880 890 900
EQLVLMPCLK RLFLNDCPKL RALPEDLHRI ANLRRIHIEG AHTLQEVDNL
910 920 930 940 950
PSVLWLKVKN NRCLRRISNL CNLKDLLAQD CPALYQAENL ISLKRLYMVD
960 970 980
CHNAKQFRMS LLEDQQLAVH VVTVGADGRD IFPDESLYN
Length:989
Mass (Da):113,031
Last modified:March 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E280A4A0408E8E1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KF741800 Genomic DNA Translation: AIR72970.1
KF741801 Genomic DNA Translation: AIR72971.1
KF741825 Genomic DNA Translation: AIR72995.1
KF741826 Genomic DNA Translation: AIR72996.1
AB379817 Genomic DNA Translation: BAH20864.1

NCBI Reference Sequences

More...
RefSeqi
XP_015644979.1, XM_015789493.1
XP_015644988.1, XM_015789502.1
XP_015644997.1, XM_015789511.1
XP_015645005.1, XM_015789519.1
XP_015645013.1, XM_015789527.1
XP_015645021.1, XM_015789535.1
XP_015645024.1, XM_015789538.1
XP_015645031.1, XM_015789545.1
XP_015645040.1, XM_015789554.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os01t0149500-01; Os01t0149500-01; Os01g0149500

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4324511

Gramene; a comparative resource for plants

More...
Gramenei
Os01t0149500-01; Os01t0149500-01; Os01g0149500

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4324511

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF741800 Genomic DNA Translation: AIR72970.1
KF741801 Genomic DNA Translation: AIR72971.1
KF741825 Genomic DNA Translation: AIR72995.1
KF741826 Genomic DNA Translation: AIR72996.1
AB379817 Genomic DNA Translation: BAH20864.1
RefSeqiXP_015644979.1, XM_015789493.1
XP_015644988.1, XM_015789502.1
XP_015644997.1, XM_015789511.1
XP_015645005.1, XM_015789519.1
XP_015645013.1, XM_015789527.1
XP_015645021.1, XM_015789535.1
XP_015645024.1, XM_015789538.1
XP_015645031.1, XM_015789545.1
XP_015645040.1, XM_015789554.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblPlantsiOs01t0149500-01; Os01t0149500-01; Os01g0149500
GeneIDi4324511
GrameneiOs01t0149500-01; Os01t0149500-01; Os01g0149500
KEGGiosa:4324511

Phylogenomic databases

eggNOGiKOG4658 Eukaryota
COG4886 LUCA
OrthoDBi127153at2759

Family and domain databases

CDDicd14798 RX-CC_like, 1 hit
Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR032675 LRR_dom_sf
IPR002182 NB-ARC
IPR027417 P-loop_NTPase
IPR038005 RX-like_CC
IPR041118 Rx_N
PfamiView protein in Pfam
PF00931 NB-ARC, 1 hit
PF18052 Rx_N, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2ZP99_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2ZP99
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: June 17, 2020
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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