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UniProtKB - A2Y7G0 (A2Y7G0_ORYSI)

Entry version 54 (07 Oct 2020)
Sequence version 1 (20 Mar 2007)
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Protein

DDT domain-containing protein

Gene

OsI_20978

Organism
Oryza sativa subsp. indica (Rice)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscriptionARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DDT domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:OsI_20978Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. indica (Rice)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39946 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007015 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		A2Y7G0

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini147 – 206DDTInterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 35DisorderedSequence analysisAdd BLAST35
Regioni426 – 453DisorderedSequence analysisAdd BLAST28
Regioni497 – 548DisorderedSequence analysisAdd BLAST52
Regioni642 – 672DisorderedSequence analysisAdd BLAST31
Regioni1098 – 1384DisorderedSequence analysisAdd BLAST287

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili43 – 81Sequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1193 – 1207BasicSequence analysisAdd BLAST15
Compositional biasi1233 – 1248PolarSequence analysisAdd BLAST16
Compositional biasi1257 – 1271PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1311 – 1378AcidicSequence analysisAdd BLAST68

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001241_0_1_1

Identification of Orthologs from Complete Genome Data

More...OMAi		WKMQISD

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007759, Asxl_HARE-HTH
IPR018501, DDT_dom
IPR028942, WHIM1_dom
IPR028941, WHIM2_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02791, DDT, 1 hit
PF05066, HARE-HTH, 1 hit
PF15612, WHIM1, 1 hit
PF15613, WSD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00571, DDT, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50827, DDT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2Y7G0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERNDRERRK EEERLLREKQ KEEERFQREQ RREHKRMEKY LLKQSLRAEK 
        60         70         80         90        100
IRQKEELRKE KEAARQKAAN ERATARRIAR EYMELMEDER LELMELVSRS 
       110        120        130        140        150
KGLPSMLSLD SDTLQQLDSF RGMLRQFPSE IVRLKVPFSI KPWTSSEDNI 
       160        170        180        190        200
GNLLMVWKFF ITFADVLGIP SFTLDEFVQS LHDYDSRLLG ELHVALLKSI 
       210        220        230        240        250
IKDIEDVART PSVASGMTAN PGGGHPQIVE GAYDWGFNIL AWQRHLNLLT 
       260        270        280        290        300
WPEILRQFGL SAGLGPQLRK RNAENVNNHD DNEGRNGEDV ISILRSGSAA 
       310        320        330        340        350
VNAAAKMKER GYGNRRRSRH RLTPGTVKFA AFHVLSLEGS QGLTILEVAE 
       360        370        380        390        400
KIQKSGLRDL TTSKTPEASI SAALSRDSKL FERTAPSTYC VKTPYRKDPA 
       410        420        430        440        450
DSEAVLAAAR EKIRVFQNTI SECEEVEKDV DDAERDEDSE CDDADDDPDG 
       460        470        480        490        500
DEVNIEEKDV KASLVKAQDG GMPTAVGDIK KETNSIVNSL TTPLIHTKSS 
       510        520        530        540        550
ESSSLRTLDK SVQVRTTSDL PAEISSDNHE GASDSAQDAE IDESNQGESW 
       560        570        580        590        600
VQGLAEGDYC DLSVEERLNA LVALIGVATE GNSIRAVLEE RLEAASALKK 
       610        620        630        640        650
QMWAEAQLDK RRSREEFSSK MQYDSGMGLK TDVDQQNTLA ESNLTPVHNL 
       660        670        680        690        700
VKDSNGNGSL VNNELPVDQQ SQPNACSVVH ERNGVRQEFS ANPENLSGQQ 
       710        720        730        740        750
YVTSEKTRSQ LKSYIGHKAE QLHVYRSLPL GQDRRRNRYW QFSTSASPDD 
       760        770        780        790        800
PGSGRIFFES RDGYWRLIDS IETFDALVSS LDTRGIRESH LHSMLQSIEP 
       810        820        830        840        850
TFKEAIGRKR CASIEPSAGR VLKNGTSEII SPNHSNEFGS PCSTLSGVAT 
       860        870        880        890        900
DSAMAYSDSF RIELGRNDVE KTAISERADL FIKWMWKECN NHQPTCAMKH 
       910        920        930        940        950
GKKRCSELIQ CCDFCYQIYL AEETHCASCH KTFKSIHNIS EHSSQCEEKR 
       960        970        980        990       1000
RTDPNWKMQI SDDSVPVGLR LLKLLLATVE ASVPAEALEP FWTDVYRKSW 
      1010       1020       1030       1040       1050
GVKLYSTSST KEVFEMLTIL EGAIRRDFLS SDFETTTELL NLSTQDSASR 
      1060       1070       1080       1090       1100
NTVPRSGSAD VLPWVPDTVA AVVLRLLDLD SAISYTLRQK VGSNKERGAG 
      1110       1120       1130       1140       1150
EFMKLPPRYT PAKTKQETEP MGTGFDRQET WLTPSNGRGG RGGRGRGSRG 
      1160       1170       1180       1190       1200
GSRGGRSRSR GGKVPRGISS SPKIEFRGYS ASAVSSEKAP RKYARRGRNR 
      1210       1220       1230       1240       1250
GRGRGLRTVR PRQPSDIGAR SIPKPNLLGS FSMLRNAKHT TAMESPQSSG 
      1260       1270       1280       1290       1300
AEEWGLERRP SYVKDDEDNS ASQSEESSEE NSEPMNEEYD ELLPDYSRDN 
      1310       1320       1330       1340       1350
SGSSPLQMMD DGSDDNEEDA EGDEDGEEDG EDYDAEQHVD EDNDDAEMGE 
      1360       1370       1380 
DDVEDNDDGD GGGGGAENGD EDEDGTSYSS EYSE
Length:1,384
Mass (Da):154,638
Last modified:March 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C81C3D1859A2C53
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CM000130 Genomic DNA Translation: EAY99020.1

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		BGIOSGA017565-TA; BGIOSGA017565-PA; BGIOSGA017565

Gramene; a comparative resource for plants

More...Gramenei		BGIOSGA017565-TA; BGIOSGA017565-PA; BGIOSGA017565

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000130 Genomic DNA Translation: EAY99020.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PRIDEiA2Y7G0

Genome annotation databases

EnsemblPlantsiBGIOSGA017565-TA; BGIOSGA017565-PA; BGIOSGA017565
GrameneiBGIOSGA017565-TA; BGIOSGA017565-PA; BGIOSGA017565

Phylogenomic databases

HOGENOMiCLU_001241_0_1_1
OMAiWKMQISD

Family and domain databases

InterProiView protein in InterPro
IPR007759, Asxl_HARE-HTH
IPR018501, DDT_dom
IPR028942, WHIM1_dom
IPR028941, WHIM2_dom
PfamiView protein in Pfam
PF02791, DDT, 1 hit
PF05066, HARE-HTH, 1 hit
PF15612, WHIM1, 1 hit
PF15613, WSD, 1 hit
SMARTiView protein in SMART
SM00571, DDT, 1 hit
PROSITEiView protein in PROSITE
PS50827, DDT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2Y7G0_ORYSI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2Y7G0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: October 7, 2020
This is version 54 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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