UniProtKB - A2VDJ0 (T131L_HUMAN)

BLAST

>sp|A2VDJ0|T131L_HUMAN Transmembrane protein 131-like OS=Homo sapiens OX=9606 GN=TMEM131L PE=1 SV=2
MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGEL
LLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSR
DSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVL
SYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNK
VCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDS
AVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKATSCDSG
IIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRSV
VLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGAI
FAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELAN
KLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALR
SRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTEA
CPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEG
FGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPIT
VSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLE
FRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEF
MKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSRI
QNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKEDI
CTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQ
TCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGN
NQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQE
KREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCI
QESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASRG
SWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSLP
QYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPVH
NSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTWN
TPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHSTH
MENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV

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Format
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History
Entry version 96 (07 Nov 2018)
Sequence version 2 (08 Apr 2008)
Previous versions | rss
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Protein

Transmembrane protein 131-like

Gene

TMEM131L

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.1 Publication

GO - Biological processⁱ

negative regulation of canonical Wnt signaling pathway
Source: UniProtKB
Inferred from direct assayⁱ
- 23690469
negative regulation of immature T cell proliferation in thymus
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 23690469
Wnt signaling pathway Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Wnt signaling pathway

Biological process

Wnt signaling pathway

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Transmembrane protein 131-likeImported
Gene namesⁱ	Name:TMEM131LImported Synonyms:KIAA0922Imported
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 4

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000121210.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:29146 TMEM131L
MIMⁱ	616243 gene
neXtProtⁱ	NX_A2VDJ0

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	41 – 869	ExtracellularSequence analysisAdd BLAST	829
Transmembraneⁱ	870 – 890	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	891 – 1609	CytoplasmicSequence analysisAdd BLAST	719

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000121210
PharmGKBⁱ	PA128394615

Polymorphism and mutation databases

BioMutaⁱ	KIAA0922

BioMutaⁱ

KIAA0922

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 40	Sequence analysisAdd BLAST		40
ChainⁱPRO_0000328865	41 – 1609	Transmembrane protein 131-likeAdd BLAST		1569

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	343	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	439	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	522	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	593	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	709	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	846	N-linked (GlcNAc...) asparagineSequence analysis	1
Modified residueⁱ	1122	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Glycoprotein, Phosphoprotein

Proteomic databases

EPDⁱ	A2VDJ0
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	A2VDJ0
PaxDbⁱ	A2VDJ0
PRIDEⁱ	A2VDJ0
ProteomicsDBⁱ	541 542 [A2VDJ0-2] 543 [A2VDJ0-3] 544 [A2VDJ0-5]

PTM databases

iPTMnetⁱ	A2VDJ0
PhosphoSitePlusⁱ	A2VDJ0
SwissPalmⁱ	A2VDJ0

Expressionⁱ

Tissue specificityⁱ

Expressed in thymocytes.1 Publication

Developmental stageⁱ

During intrathymic development, transcript levels strongly increase from pro-DN1 thymocytes to DN3a cells, in which they peak, and drop immediately after beta-selection in their DN3b successors. The subcellular location of the protein also varies, from punctate cytoplasmic structures in DN1 and DN2 cells to large crescent-shaped membrane structures in DN3 cells, which preferentially localize in cell-to-cell contact zones.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000121210 Expressed in 188 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_KIAA0922
ExpressionAtlasⁱ	A2VDJ0 baseline and differential
Genevisibleⁱ	A2VDJ0 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA043472 HPA048443

HPAⁱ

HPA043472
HPA048443

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	116844, 30 interactors
IntActⁱ	A2VDJ0, 1 interactor
STRINGⁱ	9606.ENSP00000386787

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A2VDJ0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	696 – 916	Required for Wnt-signaling inhibition and LRP6 degradation1 PublicationAdd BLAST		221

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	910 – 913	Poly-Ser		4
Compositional biasⁱ	1302 – 1331	Ser-richAdd BLAST		30

Sequence similaritiesⁱ

Belongs to the TMEM131 family.Curated

Keywords - Domainⁱ

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3620 Eukaryota ENOG410Z7NH LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063614
HOGENOMⁱ	HOG000154480
HOVERGENⁱ	HBG108533
InParanoidⁱ	A2VDJ0
OMAⁱ	SESFVFF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HKE
PhylomeDBⁱ	A2VDJ0
TreeFamⁱ	TF321435

Family and domain databases

InterProⁱ	View protein in InterPro IPR039877 TMEM131-like IPR022113 TMEM131-like_dom
PANTHERⁱ	PTHR22050 PTHR22050, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12371 TMEM131_like, 1 hit

Sequences (5+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 5 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: A2VDJ0-1) [UniParc]FASTA Add to basket

Also known as: L1 Publication

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

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        10         20         30         40         50
MAGLRRPQPG CYCRTAAAVN LLLGVFQVLL PCCRPGGAQG QAIEPLPNVV 
        60         70         80         90        100
ELWQAEEGEL LLPTQGDSEE GLEEPSQEQS FSDKLFSGKG LHFQPSVLDF 
       110        120        130        140        150
GIQFLGHPVA KILHAYNPSR DSEVVVNSVF AAAGHFHVPP VPCRVIPAMG 
       160        170        180        190        200
KTSFRIIFLP TEEGSIESSL FINTSSYGVL SYHVSGIGTR RISTEGSAKQ 
       210        220        230        240        250
LPNAYFLLPK VQSIQLSQMQ AETTNTSLLQ VQLECSLHNK VCQQLKGCYL 
       260        270        280        290        300
ESDDVLRLQM SIMVTMENFS KEFEENTQHL LDHLSIVYVA TDESETSDDS 
       310        320        330        340        350
AVNMYILHSG NSLIWIQDIR HFSQRDALSL QFEPVLLPTS TTNFTKIASF 
       360        370        380        390        400
TCKATSCDSG IIEDVKKTTH TPTLKACLFS SVAQGYFRMD SSATQFHIET 
       410        420        430        440        450
HENTSGLWSI WYRNHFDRSV VLNDVFLSKE TKHMLKILNF TGPLFLPPGC 
       460        470        480        490        500
WNIFSLKLAV KDIAINLFTN VFLTTNIGAI FAIPLQIYSA PTKEGSLGFE 
       510        520        530        540        550
VIAHCGMHYF MGKSKAGNPN WNGSLSLDQS TWNVDSELAN KLYERWKKYK 
       560        570        580        590        600
NGDVCKRNVL GTTRFAHLKK SKESESFVFF LPRLIAEPGL MLNFSATALR 
       610        620        630        640        650
SRMIKYFVVQ NPSSWPVSLQ LLPLSLYPKP EALVHLLHRW FGTDMQMINF 
       660        670        680        690        700
TTGEFQLTEA CPYLGTHSEE SRFGILHLHL QPLEMKRVGV VFTPADYGKV 
       710        720        730        740        750
TSLILIRNNL TVIDMIGVEG FGARELLKVG GRLPGAGGSL RFKVPESTLM 
       760        770        780        790        800
DCRRQLKDSK QILSITKNFK VENIGPLPIT VSSLKINGYN CQGYGFEVLD 
       810        820        830        840        850
CHQFSLDPNT SRDISIVFTP DFTSSWVIRD LSLVTAADLE FRFTLNVTLP 
       860        870        880        890        900
HHLLPLCADV VPGPSWEESF WRLTVFFVSL SLLGVILIAF QQAQYILMEF 
       910        920        930        940        950
MKTRQRQNAS SSSQQNNGPM DVISPHSYKS NCKNFLDTYG PSDKGRGKNC 
       960        970        980        990       1000
LPVNTPQSRI QNAAKRSPAT YGHSQKKHKC SVYYSKHKTS TAAASSTSTT 
      1010       1020       1030       1040       1050
TEEKQTSPLG SSLPAAKEDI CTDAMRENWI SLRYASGINV NLQKNLTLPK 
      1060       1070       1080       1090       1100
NLLNKEENTL KNTIVFSNPS SECSMKEGIQ TCMFPKETDI KTSENTAEFK 
      1110       1120       1130       1140       1150
ERELCPLKTS KKLPENHLPR NSPQYHQPDL PEISRKNNGN NQQVPVKNEV 
      1160       1170       1180       1190       1200
DHCENLKKVD TKPSSEKKIH KTSREDMFSE KQDIPFVEQE DPYRKKKLQE 
      1210       1220       1230       1240       1250
KREGNLQNLN WSKSRTCRKN KKRGVAPVSR PPEQSDLKLV CSDFERSELS 
      1260       1270       1280       1290       1300
SDINVRSWCI QESTREVCKA DAEIASSLPA AQREAEGYYQ KPEKKCVDKF 
      1310       1320       1330       1340       1350
CSDSSSDCGS SSGSVRASRG SWGSWSSTSS SDGDKKPMVD AQHFLPAGDS 
      1360       1370       1380       1390       1400
VSQNDFPSEA PISLNLSHNI CNPMTVNSLP QYAEPSCPSL PAGPTGVEED 
      1410       1420       1430       1440       1450
KGLYSPGDLW PTPPVCVTSS LNCTLENGVP CVIQESAPVH NSFIDWSATC 
      1460       1470       1480       1490       1500
EGQFSSAYCP LELNDYNAFP EENMNYANGF PCPADVQTDF IDHNSQSTWN 
      1510       1520       1530       1540       1550
TPPNMPAAWG HASFISSPPY LTSTRSLSPM SGLFGSIWAP QSDVYENCCP 
      1560       1570       1580       1590       1600
INPTTEHSTH MENQAVVCKE YYPGFNPFRA YMNLDIWTTT ANRNANFPLS 

RDSSYCGNV

Length:1,609

Mass (Da):179,339

Last modified:April 8, 2008 - v2

Checksum:ⁱ7F9D2EC0BC959210

Isoform 2 (identifier: A2VDJ0-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-370: Missing.
371-380: TPTLKACLFS → MLLVLECVLF

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        10         20         30         40         50
MLLVLECVLF SVAQGYFRMD SSATQFHIET HENTSGLWSI WYRNHFDRSV 
        60         70         80         90        100
VLNDVFLSKE TKHMLKILNF TGPLFLPPGC WNIFSLKLAV KDIAINLFTN 
       110        120        130        140        150
VFLTTNIGAI FAIPLQIYSA PTKEGSLGFE VIAHCGMHYF MGKSKAGNPN 
       160        170        180        190        200
WNGSLSLDQS TWNVDSELAN KLYERWKKYK NGDVCKRNVL GTTRFAHLKK 
       210        220        230        240        250
SKESESFVFF LPRLIAEPGL MLNFSATALR SRMIKYFVVQ NPSSWPVSLQ 
       260        270        280        290        300
LLPLSLYPKP EALVHLLHRW FGTDMQMINF TTGEFQLTEA CPYLGTHSEE 
       310        320        330        340        350
SRFGILHLHL QPLEMKRVGV VFTPADYGKV TSLILIRNNL TVIDMIGVEG 
       360        370        380        390        400
FGARELLKVG GRLPGAGGSL RFKVPESTLM DCRRQLKDSK QILSITKNFK 
       410        420        430        440        450
VENIGPLPIT VSSLKINGYN CQGYGFEVLD CHQFSLDPNT SRDISIVFTP 
       460        470        480        490        500
DFTSSWVIRD LSLVTAADLE FRFTLNVTLP HHLLPLCADV VPGPSWEESF 
       510        520        530        540        550
WRLTVFFVSL SLLGVILIAF QQAQYILMEF MKTRQRQNAS SSSQQNNGPM 
       560        570        580        590        600
DVISPHSYKS NCKNFLDTYG PSDKGRGKNC LPVNTPQSRI QNAAKRSPAT 
       610        620        630        640        650
YGHSQKKHKC SVYYSKHKTS TAAASSTSTT TEEKQTSPLG SSLPAAKEDI 
       660        670        680        690        700
CTDAMRENWI SLRYASGINV NLQKNLTLPK NLLNKEENTL KNTIVFSNPS 
       710        720        730        740        750
SECSMKEGIQ TCMFPKETDI KTSENTAEFK ERELCPLKTS KKLPENHLPR 
       760        770        780        790        800
NSPQYHQPDL PEISRKNNGN NQQVPVKNEV DHCENLKKVD TKPSSEKKIH 
       810        820        830        840        850
KTSREDMFSE KQDIPFVEQE DPYRKKKLQE KREGNLQNLN WSKSRTCRKN 
       860        870        880        890        900
KKRGVAPVSR PPEQSDLKLV CSDFERSELS SDINVRSWCI QESTREVCKA 
       910        920        930        940        950
DAEIASSLPA AQREAEGYYQ KPEKKCVDKF CSDSSSDCGS SSGSVRASRG 
       960        970        980        990       1000
SWGSWSSTSS SDGDKKPMVD AQHFLPAGDS VSQNDFPSEA PISLNLSHNI 
      1010       1020       1030       1040       1050
CNPMTVNSLP QYAEPSCPSL PAGPTGVEED KGLYSPGDLW PTPPVCVTSS 
      1060       1070       1080       1090       1100
LNCTLENGVP CVIQESAPVH NSFIDWSATC EGQFSSAYCP LELNDYNAFP 
      1110       1120       1130       1140       1150
EENMNYANGF PCPADVQTDF IDHNSQSTWN TPPNMPAAWG HASFISSPPY 
      1160       1170       1180       1190       1200
LTSTRSLSPM SGLFGSIWAP QSDVYENCCP INPTTEHSTH MENQAVVCKE 
      1210       1220       1230 
YYPGFNPFRA YMNLDIWTTT ANRNANFPLS RDSSYCGNV

Note: No experimental confirmation available.

Show »

Length:1,239

Mass (Da):138,688

Checksum:ⁱCB9238E5A0D84146

Isoform 3 (identifier: A2VDJ0-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
353-353: K → KA
557-640: Missing.

« Hide

        10         20         30         40         50
MAGLRRPQPG CYCRTAAAVN LLLGVFQVLL PCCRPGGAQG QAIEPLPNVV 
        60         70         80         90        100
ELWQAEEGEL LLPTQGDSEE GLEEPSQEQS FSDKLFSGKG LHFQPSVLDF 
       110        120        130        140        150
GIQFLGHPVA KILHAYNPSR DSEVVVNSVF AAAGHFHVPP VPCRVIPAMG 
       160        170        180        190        200
KTSFRIIFLP TEEGSIESSL FINTSSYGVL SYHVSGIGTR RISTEGSAKQ 
       210        220        230        240        250
LPNAYFLLPK VQSIQLSQMQ AETTNTSLLQ VQLECSLHNK VCQQLKGCYL 
       260        270        280        290        300
ESDDVLRLQM SIMVTMENFS KEFEENTQHL LDHLSIVYVA TDESETSDDS 
       310        320        330        340        350
AVNMYILHSG NSLIWIQDIR HFSQRDALSL QFEPVLLPTS TTNFTKIASF 
       360        370        380        390        400
TCKAATSCDS GIIEDVKKTT HTPTLKACLF SSVAQGYFRM DSSATQFHIE 
       410        420        430        440        450
THENTSGLWS IWYRNHFDRS VVLNDVFLSK ETKHMLKILN FTGPLFLPPG 
       460        470        480        490        500
CWNIFSLKLA VKDIAINLFT NVFLTTNIGA IFAIPLQIYS APTKEGSLGF 
       510        520        530        540        550
EVIAHCGMHY FMGKSKAGNP NWNGSLSLDQ STWNVDSELA NKLYERWKKY 
       560        570        580        590        600
KNGDVCKFGT DMQMINFTTG EFQLTEACPY LGTHSEESRF GILHLHLQPL 
       610        620        630        640        650
EMKRVGVVFT PADYGKVTSL ILIRNNLTVI DMIGVEGFGA RELLKVGGRL 
       660        670        680        690        700
PGAGGSLRFK VPESTLMDCR RQLKDSKQIL SITKNFKVEN IGPLPITVSS 
       710        720        730        740        750
LKINGYNCQG YGFEVLDCHQ FSLDPNTSRD ISIVFTPDFT SSWVIRDLSL 
       760        770        780        790        800
VTAADLEFRF TLNVTLPHHL LPLCADVVPG PSWEESFWRL TVFFVSLSLL 
       810        820        830        840        850
GVILIAFQQA QYILMEFMKT RQRQNASSSS QQNNGPMDVI SPHSYKSNCK 
       860        870        880        890        900
NFLDTYGPSD KGRGKNCLPV NTPQSRIQNA AKRSPATYGH SQKKHKCSVY 
       910        920        930        940        950
YSKHKTSTAA ASSTSTTTEE KQTSPLGSSL PAAKEDICTD AMRENWISLR 
       960        970        980        990       1000
YASGINVNLQ KNLTLPKNLL NKEENTLKNT IVFSNPSSEC SMKEGIQTCM 
      1010       1020       1030       1040       1050
FPKETDIKTS ENTAEFKERE LCPLKTSKKL PENHLPRNSP QYHQPDLPEI 
      1060       1070       1080       1090       1100
SRKNNGNNQQ VPVKNEVDHC ENLKKVDTKP SSEKKIHKTS REDMFSEKQD 
      1110       1120       1130       1140       1150
IPFVEQEDPY RKKKLQEKRE GNLQNLNWSK SRTCRKNKKR GVAPVSRPPE 
      1160       1170       1180       1190       1200
QSDLKLVCSD FERSELSSDI NVRSWCIQES TREVCKADAE IASSLPAAQR 
      1210       1220       1230       1240       1250
EAEGYYQKPE KKCVDKFCSD SSSDCGSSSG SVRASRGSWG SWSSTSSSDG 
      1260       1270       1280       1290       1300
DKKPMVDAQH FLPAGDSVSQ NDFPSEAPIS LNLSHNICNP MTVNSLPQYA 
      1310       1320       1330       1340       1350
EPSCPSLPAG PTGVEEDKGL YSPGDLWPTP PVCVTSSLNC TLENGVPCVI 
      1360       1370       1380       1390       1400
QESAPVHNSF IDWSATCEGQ FSSAYCPLEL NDYNAFPEEN MNYANGFPCP 
      1410       1420       1430       1440       1450
ADVQTDFIDH NSQSTWNTPP NMPAAWGHAS FISSPPYLTS TRSLSPMSGL 
      1460       1470       1480       1490       1500
FGSIWAPQSD VYENCCPINP TTEHSTHMEN QAVVCKEYYP GFNPFRAYMN 
      1510       1520 
LDIWTTTANR NANFPLSRDS SYCGNV

Note: No experimental confirmation available.

Show »

Length:1,526

Mass (Da):169,707

Checksum:ⁱ31C5F68FD8A4EBA5

Isoform 4 (identifier: A2VDJ0-5) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
353-353: K → KA

« Hide

        10         20         30         40         50
MAGLRRPQPG CYCRTAAAVN LLLGVFQVLL PCCRPGGAQG QAIEPLPNVV 
        60         70         80         90        100
ELWQAEEGEL LLPTQGDSEE GLEEPSQEQS FSDKLFSGKG LHFQPSVLDF 
       110        120        130        140        150
GIQFLGHPVA KILHAYNPSR DSEVVVNSVF AAAGHFHVPP VPCRVIPAMG 
       160        170        180        190        200
KTSFRIIFLP TEEGSIESSL FINTSSYGVL SYHVSGIGTR RISTEGSAKQ 
       210        220        230        240        250
LPNAYFLLPK VQSIQLSQMQ AETTNTSLLQ VQLECSLHNK VCQQLKGCYL 
       260        270        280        290        300
ESDDVLRLQM SIMVTMENFS KEFEENTQHL LDHLSIVYVA TDESETSDDS 
       310        320        330        340        350
AVNMYILHSG NSLIWIQDIR HFSQRDALSL QFEPVLLPTS TTNFTKIASF 
       360        370        380        390        400
TCKAATSCDS GIIEDVKKTT HTPTLKACLF SSVAQGYFRM DSSATQFHIE 
       410        420        430        440        450
THENTSGLWS IWYRNHFDRS VVLNDVFLSK ETKHMLKILN FTGPLFLPPG 
       460        470        480        490        500
CWNIFSLKLA VKDIAINLFT NVFLTTNIGA IFAIPLQIYS APTKEGSLGF 
       510        520        530        540        550
EVIAHCGMHY FMGKSKAGNP NWNGSLSLDQ STWNVDSELA NKLYERWKKY 
       560        570        580        590        600
KNGDVCKRNV LGTTRFAHLK KSKESESFVF FLPRLIAEPG LMLNFSATAL 
       610        620        630        640        650
RSRMIKYFVV QNPSSWPVSL QLLPLSLYPK PEALVHLLHR WFGTDMQMIN 
       660        670        680        690        700
FTTGEFQLTE ACPYLGTHSE ESRFGILHLH LQPLEMKRVG VVFTPADYGK 
       710        720        730        740        750
VTSLILIRNN LTVIDMIGVE GFGARELLKV GGRLPGAGGS LRFKVPESTL 
       760        770        780        790        800
MDCRRQLKDS KQILSITKNF KVENIGPLPI TVSSLKINGY NCQGYGFEVL 
       810        820        830        840        850
DCHQFSLDPN TSRDISIVFT PDFTSSWVIR DLSLVTAADL EFRFTLNVTL 
       860        870        880        890        900
PHHLLPLCAD VVPGPSWEES FWRLTVFFVS LSLLGVILIA FQQAQYILME 
       910        920        930        940        950
FMKTRQRQNA SSSSQQNNGP MDVISPHSYK SNCKNFLDTY GPSDKGRGKN 
       960        970        980        990       1000
CLPVNTPQSR IQNAAKRSPA TYGHSQKKHK CSVYYSKHKT STAAASSTST 
      1010       1020       1030       1040       1050
TTEEKQTSPL GSSLPAAKED ICTDAMRENW ISLRYASGIN VNLQKNLTLP 
      1060       1070       1080       1090       1100
KNLLNKEENT LKNTIVFSNP SSECSMKEGI QTCMFPKETD IKTSENTAEF 
      1110       1120       1130       1140       1150
KERELCPLKT SKKLPENHLP RNSPQYHQPD LPEISRKNNG NNQQVPVKNE 
      1160       1170       1180       1190       1200
VDHCENLKKV DTKPSSEKKI HKTSREDMFS EKQDIPFVEQ EDPYRKKKLQ 
      1210       1220       1230       1240       1250
EKREGNLQNL NWSKSRTCRK NKKRGVAPVS RPPEQSDLKL VCSDFERSEL 
      1260       1270       1280       1290       1300
SSDINVRSWC IQESTREVCK ADAEIASSLP AAQREAEGYY QKPEKKCVDK 
      1310       1320       1330       1340       1350
FCSDSSSDCG SSSGSVRASR GSWGSWSSTS SSDGDKKPMV DAQHFLPAGD 
      1360       1370       1380       1390       1400
SVSQNDFPSE APISLNLSHN ICNPMTVNSL PQYAEPSCPS LPAGPTGVEE 
      1410       1420       1430       1440       1450
DKGLYSPGDL WPTPPVCVTS SLNCTLENGV PCVIQESAPV HNSFIDWSAT 
      1460       1470       1480       1490       1500
CEGQFSSAYC PLELNDYNAF PEENMNYANG FPCPADVQTD FIDHNSQSTW 
      1510       1520       1530       1540       1550
NTPPNMPAAW GHASFISSPP YLTSTRSLSP MSGLFGSIWA PQSDVYENCC 
      1560       1570       1580       1590       1600
PINPTTEHST HMENQAVVCK EYYPGFNPFR AYMNLDIWTT TANRNANFPL 
      1610
SRDSSYCGNV

Note: No experimental confirmation available.

Show »

Length:1,610

Mass (Da):179,410

Checksum:ⁱ5D46F0BE83EB56CE

Isoform 5 (identifier: A2VDJ0-6) [UniParc]FASTA Add to basket

Also known as: S1 Publication

The sequence of this isoform differs from the canonical sequence as follows:
1-148: Missing.
353-353: K → KA

« Hide

        10         20         30         40         50
MGKTSFRIIF LPTEEGSIES SLFINTSSYG VLSYHVSGIG TRRISTEGSA 
        60         70         80         90        100
KQLPNAYFLL PKVQSIQLSQ MQAETTNTSL LQVQLECSLH NKVCQQLKGC 
       110        120        130        140        150
YLESDDVLRL QMSIMVTMEN FSKEFEENTQ HLLDHLSIVY VATDESETSD 
       160        170        180        190        200
DSAVNMYILH SGNSLIWIQD IRHFSQRDAL SLQFEPVLLP TSTTNFTKIA 
       210        220        230        240        250
SFTCKAATSC DSGIIEDVKK TTHTPTLKAC LFSSVAQGYF RMDSSATQFH 
       260        270        280        290        300
IETHENTSGL WSIWYRNHFD RSVVLNDVFL SKETKHMLKI LNFTGPLFLP 
       310        320        330        340        350
PGCWNIFSLK LAVKDIAINL FTNVFLTTNI GAIFAIPLQI YSAPTKEGSL 
       360        370        380        390        400
GFEVIAHCGM HYFMGKSKAG NPNWNGSLSL DQSTWNVDSE LANKLYERWK 
       410        420        430        440        450
KYKNGDVCKR NVLGTTRFAH LKKSKESESF VFFLPRLIAE PGLMLNFSAT 
       460        470        480        490        500
ALRSRMIKYF VVQNPSSWPV SLQLLPLSLY PKPEALVHLL HRWFGTDMQM 
       510        520        530        540        550
INFTTGEFQL TEACPYLGTH SEESRFGILH LHLQPLEMKR VGVVFTPADY 
       560        570        580        590        600
GKVTSLILIR NNLTVIDMIG VEGFGARELL KVGGRLPGAG GSLRFKVPES 
       610        620        630        640        650
TLMDCRRQLK DSKQILSITK NFKVENIGPL PITVSSLKIN GYNCQGYGFE 
       660        670        680        690        700
VLDCHQFSLD PNTSRDISIV FTPDFTSSWV IRDLSLVTAA DLEFRFTLNV 
       710        720        730        740        750
TLPHHLLPLC ADVVPGPSWE ESFWRLTVFF VSLSLLGVIL IAFQQAQYIL 
       760        770        780        790        800
MEFMKTRQRQ NASSSSQQNN GPMDVISPHS YKSNCKNFLD TYGPSDKGRG 
       810        820        830        840        850
KNCLPVNTPQ SRIQNAAKRS PATYGHSQKK HKCSVYYSKH KTSTAAASST 
       860        870        880        890        900
STTTEEKQTS PLGSSLPAAK EDICTDAMRE NWISLRYASG INVNLQKNLT 
       910        920        930        940        950
LPKNLLNKEE NTLKNTIVFS NPSSECSMKE GIQTCMFPKE TDIKTSENTA 
       960        970        980        990       1000
EFKERELCPL KTSKKLPENH LPRNSPQYHQ PDLPEISRKN NGNNQQVPVK 
      1010       1020       1030       1040       1050
NEVDHCENLK KVDTKPSSEK KIHKTSREDM FSEKQDIPFV EQEDPYRKKK 
      1060       1070       1080       1090       1100
LQEKREGNLQ NLNWSKSRTC RKNKKRGVAP VSRPPEQSDL KLVCSDFERS 
      1110       1120       1130       1140       1150
ELSSDINVRS WCIQESTREV CKADAEIASS LPAAQREAEG YYQKPEKKCV 
      1160       1170       1180       1190       1200
DKFCSDSSSD CGSSSGSVRA SRGSWGSWSS TSSSDGDKKP MVDAQHFLPA 
      1210       1220       1230       1240       1250
GDSVSQNDFP SEAPISLNLS HNICNPMTVN SLPQYAEPSC PSLPAGPTGV 
      1260       1270       1280       1290       1300
EEDKGLYSPG DLWPTPPVCV TSSLNCTLEN GVPCVIQESA PVHNSFIDWS 
      1310       1320       1330       1340       1350
ATCEGQFSSA YCPLELNDYN AFPEENMNYA NGFPCPADVQ TDFIDHNSQS 
      1360       1370       1380       1390       1400
TWNTPPNMPA AWGHASFISS PPYLTSTRSL SPMSGLFGSI WAPQSDVYEN 
      1410       1420       1430       1440       1450
CCPINPTTEH STHMENQAVV CKEYYPGFNP FRAYMNLDIW TTTANRNANF 
      1460 
PLSRDSSYCG NV

Note: No experimental confirmation available.

Show »

Length:1,462

Mass (Da):163,518

Checksum:ⁱA83EFE7797FC2590

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

F8WEQ2	F8WEQ2_HUMAN	Transmembrane protein 131-like Transmembrane protein 131-like	TMEM131L	71	Annotation score:
H0Y2M0	H0Y2M0_HUMAN	Transmembrane protein 131-like Transmembrane protein 131-like	TMEM131L	1,387	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	171	F → S in BAG52515 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_042551	604	I → V. Corresponds to variant dbSNP:rs7669418Ensembl.	1
Natural variantⁱVAR_042552	645	M → T1 PublicationCorresponds to variant dbSNP:rs17370297Ensembl.	1
Natural variantⁱVAR_042553	1110	S → Y. Corresponds to variant dbSNP:rs755078Ensembl.	1
Natural variantⁱVAR_042554	1254	N → S. Corresponds to variant dbSNP:rs35018723Ensembl.	1
Natural variantⁱVAR_042555	1392	A → P. Corresponds to variant dbSNP:rs35543386Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_032826	1 – 370	Missing in isoform 2. 1 PublicationAdd BLAST	370
Alternative sequenceⁱVSP_057633	1 – 148	Missing in isoform 5. Add BLAST	148
Alternative sequenceⁱVSP_032827	353	K → KA in isoform 3, isoform 4 and isoform 5. 3 Publications	1
Alternative sequenceⁱVSP_032828	371 – 380	TPTLKACLFS → MLLVLECVLF in isoform 2. 1 Publication	10
Alternative sequenceⁱVSP_032829	557 – 640	Missing in isoform 3. 1 PublicationAdd BLAST	84

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL136932 mRNA Translation: CAB66866.1 AC106865 Genomic DNA No translation available. AC116648 Genomic DNA No translation available. CH471056 Genomic DNA Translation: EAX04957.1 CH471056 Genomic DNA Translation: EAX04958.1 AK092270 mRNA Translation: BAG52515.1 BC044932 mRNA Translation: AAH44932.1 BC131505 mRNA Translation: AAI31506.1 AB023139 mRNA Translation: BAA76766.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3783.2 [A2VDJ0-1] CCDS47148.1 [A2VDJ0-5]
NCBI Reference Sequences More...RefSeqⁱ	NP_001124479.1, NM_001131007.1 [A2VDJ0-5] NP_056011.3, NM_015196.3 [A2VDJ0-1]
UniGeneⁱ	Hs.732450

Genome annotation databases

Ensemblⁱ	ENST00000409663; ENSP00000386574; ENSG00000121210 [A2VDJ0-1] ENST00000409959; ENSP00000386787; ENSG00000121210 [A2VDJ0-5]
GeneIDⁱ	23240
KEGGⁱ	hsa:23240
UCSC genome browser More...UCSCⁱ	uc003inm.5 human [A2VDJ0-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
A2VDJ0	Uncharacterized protein		RHIRO		1621	UniRef90_A2VDJ0
Transmembrane 131 like		PANTR		1617
Uncharacterized protein		PANPA		1617
Uncharacterized protein		MACMU		1614
Uncharacterized protein		Cebus capucinus imitator		1614
+85
A2VDJ0-3	Transmembrane protein 131-like (Fragment)		HUMAN		1387	UniRef90_A2VDJ0-3
Uncharacterized protein		MACMU		1387
TMEM131L isoform 5 (Fragment)		PANTR		1387
TMEM131L isoform 2 (Fragment)		PONAB		1386
UPI0005CFF4DE		HUMAN		1555

Protein	Similar proteins		Species	Score	Length	Source
A2VDJ0	Transmembrane protein 131-like		BOVIN		1598	UniRef50_A2VDJ0
Uncharacterized protein		RHIRO		1621
Uncharacterized protein		PANPA		1617
Transmembrane 131 like		PANTR		1617
Uncharacterized protein		Cebus capucinus imitator		1614
+471
A2VDJ0-3	Transmembrane protein 131-like (Fragment)		HUMAN		1387	UniRef50_A2VDJ0-3
Uncharacterized protein		MACMU		1387
TMEM131L isoform 5 (Fragment)		PANTR		1387
TMEM131L isoform 2 (Fragment)		PONAB		1386
Transmembrane 131 like		GORGO		1569
+26

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL136932 mRNA Translation: CAB66866.1 AC106865 Genomic DNA No translation available. AC116648 Genomic DNA No translation available. CH471056 Genomic DNA Translation: EAX04957.1 CH471056 Genomic DNA Translation: EAX04958.1 AK092270 mRNA Translation: BAG52515.1 BC044932 mRNA Translation: AAH44932.1 BC131505 mRNA Translation: AAI31506.1 AB023139 mRNA Translation: BAA76766.1
CCDSⁱ	CCDS3783.2 [A2VDJ0-1] CCDS47148.1 [A2VDJ0-5]
RefSeqⁱ	NP_001124479.1, NM_001131007.1 [A2VDJ0-5] NP_056011.3, NM_015196.3 [A2VDJ0-1]
UniGeneⁱ	Hs.732450

3D structure databases

ProteinModelPortalⁱ	A2VDJ0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	116844, 30 interactors
IntActⁱ	A2VDJ0, 1 interactor
STRINGⁱ	9606.ENSP00000386787

PTM databases

iPTMnetⁱ	A2VDJ0
PhosphoSitePlusⁱ	A2VDJ0
SwissPalmⁱ	A2VDJ0

Polymorphism and mutation databases

BioMutaⁱ	KIAA0922

BioMutaⁱ

KIAA0922

Proteomic databases

EPDⁱ	A2VDJ0
MaxQBⁱ	A2VDJ0
PaxDbⁱ	A2VDJ0
PRIDEⁱ	A2VDJ0
ProteomicsDBⁱ	541 542 [A2VDJ0-2] 543 [A2VDJ0-3] 544 [A2VDJ0-5]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000409663; ENSP00000386574; ENSG00000121210 [A2VDJ0-1] ENST00000409959; ENSP00000386787; ENSG00000121210 [A2VDJ0-5]
GeneIDⁱ	23240
KEGGⁱ	hsa:23240
UCSCⁱ	uc003inm.5 human [A2VDJ0-1]

Organism-specific databases

CTDⁱ	23240
EuPathDBⁱ	HostDB:ENSG00000121210.15
GeneCardsⁱ	TMEM131L
H-InvDBⁱ	HIX0004579
HGNCⁱ	HGNC:29146 TMEM131L
HPAⁱ	HPA043472 HPA048443
MIMⁱ	616243 gene
neXtProtⁱ	NX_A2VDJ0
OpenTargetsⁱ	ENSG00000121210
PharmGKBⁱ	PA128394615
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3620 Eukaryota ENOG410Z7NH LUCA
GeneTreeⁱ	ENSGT00530000063614
HOGENOMⁱ	HOG000154480
HOVERGENⁱ	HBG108533
InParanoidⁱ	A2VDJ0
OMAⁱ	SESFVFF
OrthoDBⁱ	EOG091G0HKE
PhylomeDBⁱ	A2VDJ0
TreeFamⁱ	TF321435

Miscellaneous databases

ChiTaRSⁱ	KIAA0922 human
GeneWikiⁱ	KIAA0922
GenomeRNAiⁱ	23240
Protein Ontology More...PROⁱ	PR:A2VDJ0
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000121210 Expressed in 188 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_KIAA0922
ExpressionAtlasⁱ	A2VDJ0 baseline and differential
Genevisibleⁱ	A2VDJ0 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR039877 TMEM131-like IPR022113 TMEM131-like_dom
PANTHERⁱ	PTHR22050 PTHR22050, 1 hit
Pfamⁱ	View protein in Pfam PF12371 TMEM131_like, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	T131L_HUMAN
Accessionⁱ	A2VDJ0Primary (citable) accession number: A2VDJ0 Secondary accession number(s): B3KRV3 Q9Y2D7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
	Last sequence update:	April 8, 2008
	Last modified:	November 7, 2018
	This is version 96 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniProtKB - A2VDJ0 (T131L_HUMAN)

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Transmembrane protein 131-like

TMEM131L

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Other locations

Endoplasmic reticulum

Other locations

Endoplasmic reticulum

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

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Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ