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UniProtKB - A2VCX7 (A2VCX7_DANRE)
Protein
Phenylalanine--tRNA ligase alpha subunit
Gene
farsa
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- phenylalanine-tRNA ligase activity Source: UniProtKB-EC
- tRNA binding Source: InterPro
GO - Biological processi
- anatomical structure development Source: UniProt
- phenylalanyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetaseImportedARBA annotation, Ligase |
Biological process | Protein biosynthesisARBA annotation |
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Phenylalanine--tRNA ligase alpha subunitARBA annotation (EC:6.1.1.20ARBA annotation)Alternative name(s): Phenylalanyl-tRNA synthetase alpha subunitARBA annotation |
Gene namesi | Name:farsaImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-050512-2, farsa |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 229 – 491 | AA_TRNA_LIGASE_IIInterPro annotationAdd BLAST | 263 |
Sequence similaritiesi
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.ARBA annotation
Phylogenomic databases
OMAi | QIEGWVM |
Family and domain databases
Gene3Di | 3.30.930.10, 1 hit |
InterProi | View protein in InterPro IPR006195, aa-tRNA-synth_II IPR045864, aa-tRNA-synth_II/BPL/LPL IPR004529, Phe-tRNA-synth_IIc_asu IPR002319, Phenylalanyl-tRNA_Synthase IPR040724, PheRS_DBD1 IPR040586, PheRS_DBD2 IPR040725, PheRS_DBD3 IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF18552, PheRS_DBD1, 1 hit PF18554, PheRS_DBD2, 1 hit PF18553, PheRS_DBD3, 1 hit PF01409, tRNA-synt_2d, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF55681, SSF55681, 1 hit |
TIGRFAMsi | TIGR00468, pheS, 1 hit |
PROSITEi | View protein in PROSITE PS50862, AA_TRNA_LIGASE_II, 1 hit |
i Sequence
Sequence statusi: Complete.
A2VCX7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADTGLLEAL LQRVEQLDGG VDSQDVSAAL GVDHQLVVGA VKSLQALGEV
60 70 80 90 100
ISAEQKSSKH WELTGEGREI AEQGSHEARV FNAIPAEGLP QNQLMKMASG
110 120 130 140 150
KVGFSKAMSN KWIRLDKAHE GGPRVFRTVE SIEDTVRDKL QLVQNGQSAK
160 170 180 190 200
LEEKEKNELK KRKLLAEVTV KSYWITKGSS FSTTITKQET ELTPEMIASG
210 220 230 240 250
NWKEKKFKPY NFEAMGVAPD CGHLHPLMKV RTQFRQIFLE MGFTEMPTNN
260 270 280 290 300
FIESSFWNFD SLFQPQQHPA RDQHDTFFIS DPALAHEFPL DYLERVKKVH
310 320 330 340 350
SEGGYGSQGY KYDWKIEEAQ KNLLRTHTTA VSARMLYKLA QQEKFTPVKY
360 370 380 390 400
FSIDRVFRNE TLDATHLAEF HQIEGVVADY GLTLGNLMGV LHQFFTKLGI
410 420 430 440 450
TKLRFKPAYN PYTEPSMEVF SYHEGLKKWV EVGNSGVFRP EMLLPMGLPE
460 470 480 490
GVSVIAWGLS LERPTMIKYG INNIRELVGH KVNLQMVYDS PICRLDS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC128805 mRNA Translation: AAI28806.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC128805 mRNA Translation: AAI28806.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Organism-specific databases
ZFINi | ZDB-GENE-050512-2, farsa |
Phylogenomic databases
OMAi | QIEGWVM |
Family and domain databases
Gene3Di | 3.30.930.10, 1 hit |
InterProi | View protein in InterPro IPR006195, aa-tRNA-synth_II IPR045864, aa-tRNA-synth_II/BPL/LPL IPR004529, Phe-tRNA-synth_IIc_asu IPR002319, Phenylalanyl-tRNA_Synthase IPR040724, PheRS_DBD1 IPR040586, PheRS_DBD2 IPR040725, PheRS_DBD3 IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF18552, PheRS_DBD1, 1 hit PF18554, PheRS_DBD2, 1 hit PF18553, PheRS_DBD3, 1 hit PF01409, tRNA-synt_2d, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF55681, SSF55681, 1 hit |
TIGRFAMsi | TIGR00468, pheS, 1 hit |
PROSITEi | View protein in PROSITE PS50862, AA_TRNA_LIGASE_II, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A2VCX7_DANRE | |
Accessioni | A2VCX7Primary (citable) accession number: A2VCX7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 20, 2007 |
Last sequence update: | March 20, 2007 | |
Last modified: | January 19, 2022 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |