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Protein
Submitted name:

MAP/microtubule affinity-regulating kinase 3

Gene

MARK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
MAP/microtubule affinity-regulating kinase 3Imported
Gene namesi
Name:MARK3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000075413.17
HGNCiHGNC:6897 MARK3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000075413

PTM / Processingi

Proteomic databases

EPDiA2SY06
MaxQBiA2SY06
PeptideAtlasiA2SY06
PRIDEiA2SY06

Expressioni

Gene expression databases

BgeeiENSG00000075413 Expressed in 228 organ(s), highest expression level in cerebellar hemisphere
ExpressionAtlasiA2SY06 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini282 – 331KA1InterPro annotationAdd BLAST50

Phylogenomic databases

GeneTreeiENSGT00900000140806
HOGENOMiHOG000233025
HOVERGENiHBG052453

Family and domain databases

InterProiView protein in InterPro
IPR028375 KA1/Ssp2_C
IPR001772 KA1_dom
IPR033624 MARK/par1
IPR033628 MARK3
PANTHERiPTHR24346 PTHR24346, 1 hit
PTHR24346:SF1 PTHR24346:SF1, 1 hit
PfamiView protein in Pfam
PF02149 KA1, 1 hit
SUPFAMiSSF103243 SSF103243, 1 hit
PROSITEiView protein in PROSITE
PS50032 KA1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.iShow all

A2SY06-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
APASPMLGNA SNPNKADIPE RKKSSTVPSS NTASGGMTRR NTYVCSERTT
60 70 80 90 100
ADRHSVIQNG KENSLTEMFA YAASPASVCT STCRLRHQKS MSMSASGHPK
110 120 130 140 150
MMLPPIDSEG DNFKAITIPD QRTPVASTHS ISSAATPDRI RFPRGTASRS
160 170 180 190 200
TFHGQPRERR TATYNGPPAS PSLSHEATPL SQTRSRGSTN LFSKLTSKLT
210 220 230 240 250
RRLPTEYERN GRYEGSSRNV SAEQKDENKE AKPRSLRFTW SMKTTSSMDP
260 270 280 290 300
GDMMREIRKV LDANNCDYEQ RERFLLFCVH GDGHAENLVQ WEMEVCKLPR
310 320 330
LSLNGVRFKR ISGTSIAFKN IASKIANELK L
Length:331
Mass (Da):36,705
Last modified:March 6, 2007 - v1
Checksum:iCC55BB93B223E992
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P27448MARK3_HUMAN
MAP/microtubule affinity-regulating...
MARK3 CTAK1, EMK2
753Annotation score:
H0YIY6H0YIY6_HUMAN
Non-specific serine/threonine prote...
MARK3
505Annotation score:
J3KNR0J3KNR0_HUMAN
Non-specific serine/threonine prote...
MARK3 hCG_25498
776Annotation score:
A0A0A0MSZ1A0A0A0MSZ1_HUMAN
Non-specific serine/threonine prote...
MARK3 hCG_25498
752Annotation score:
H0YNV4H0YNV4_HUMAN
MAP/microtubule affinity-regulating...
MARK3
178Annotation score:
H0YKJ3H0YKJ3_HUMAN
MAP/microtubule affinity-regulating...
MARK3
129Annotation score:
H0YKP9H0YKP9_HUMAN
MAP/microtubule affinity-regulating...
MARK3
222Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133367 Genomic DNA No translation available.
KF456011 Genomic DNA No translation available.
DQ368336 mRNA Translation: ABD15137.1
UniGeneiHs.35828

Genome annotation databases

EnsembliENST00000556744; ENSP00000451623; ENSG00000075413
UCSCiuc059fqr.1 human

Similar proteinsi

Entry informationi

Entry nameiA2SY06_HUMAN
AccessioniPrimary (citable) accession number: A2SY06
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: September 12, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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