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Protein

Maestro heat-like repeat-containing protein family member 7

Gene

Mroh7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Maestro heat-like repeat-containing protein family member 7
Alternative name(s):
HEAT repeat-containing protein 8
Gene namesi
Name:Mroh7
Synonyms:Heatr8
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1563440 Mroh7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei548 – 568HelicalSequence analysisAdd BLAST21
Transmembranei722 – 742HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002868681 – 1122Maestro heat-like repeat-containing protein family member 7Add BLAST1122

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi200N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi255N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi267N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi296N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei356PhosphoserineCombined sources1
Glycosylationi541N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi546N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiA2RUW0
PRIDEiA2RUW0

PTM databases

iPTMnetiA2RUW0
PhosphoSitePlusiA2RUW0

Expressioni

Gene expression databases

BgeeiENSRNOG00000058870 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiA2RUW0 RN

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati913 – 950HEAT 1Add BLAST38
Repeati992 – 1029HEAT 2Add BLAST38
Repeati1035 – 1072HEAT 3Add BLAST38
Repeati1080 – 1117HEAT 4Add BLAST38

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi123 – 341Ser-richAdd BLAST219

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2032 Eukaryota
ENOG410XQE8 LUCA
GeneTreeiENSGT00910000144041
HOVERGENiHBG107563
InParanoidiA2RUW0
OMAiGKDSGEM
OrthoDBiEOG091G00DQ
PhylomeDBiA2RUW0
TreeFamiTF337538

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

A2RUW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSRGTSLI LHEDPEKTPS PNSCEVPGIM SNTTPRPTPD LTLAPLPAHG
60 70 80 90 100
VALAPALHPA LSPDPEGVSG PVPNDISNPN ASGAATPSSI QINTADTDDQ
110 120 130 140 150
SLDHTPKPNL AGTLCPDSQP VPSLSSTQAT VLSPENSIKP LSEDIPKSFS
160 170 180 190 200
SKVFGLGQSN SNPSRPEPNL YIRALSREAL VRSHTISRQS SQTPLLLPSN
210 220 230 240 250
TSLDRLHSGN ISKVNLGRAQ NSNEAITLTS HTIFASVSKE ALSASWNTGS
260 270 280 290 300
KGSVNVTSNS QPRSGLNVTV THASHVSLIP GSSEGLSLHS SAQVPNSTLS
310 320 330 340 350
PSSCMTLIMG SESLSMDSSF VVTDTSTLTL SSHRDYSEDN SIRTMPLEEN
360 370 380 390 400
LGKWDSLQGV TAFRSPPEGT SEDAKANESE KRDHDNDTAL VENIISYQKN
410 420 430 440 450
QDEVEVTGEK ETTVKMMMRK IQEEPLDSLL SPARRQAMEI LAQLSHTKPI
460 470 480 490 500
LSVRERVELV NTCVRSVFSL PSVQAMQEKD ESKAEVIQTL YHQTLDSLQK
510 520 530 540 550
LLNALFIEDP TPAGLKSILE PLGPWMNSGK VHERARAVNS NVSVLNYTLV
560 570 580 590 600
TLPFFVSSGF PTLGLLLGRL LLRIGDPDEE IGREALDGIT ILYTILDLQK
610 620 630 640 650
RTKNKEEINK KELYETNKRF LGPYNPASPC QNILRVIAEF GDFLGPQQVR
660 670 680 690 700
DLLLAALEGL KDISETQGKD SIEMMQLASE VMLSSVLEWY RHRALEVIPE
710 720 730 740 750
IMQGIYMQLS HIQEPRAREV ALLPISFLAS SFMTEVVVAL LMCPLPLDSN
760 770 780 790 800
GAEMWRQLIL RKPSCDVRDL LDLLLTSLKE KPVTKKGRAS IVPLAAASGL
810 820 830 840 850
CELLSVNSCV GRVRRIYPQL LLALLIQVHY HIGLNLPSRV APRKDSKDDI
860 870 880 890 900
QPPLFVPVRW MVKVVKTLLL KMGCSYESAF LEEQGGWELM GQAESHYRAV
910 920 930 940 950
SLLARAMVHY SCQELCRILY LLIPLLERGD ERHKITATAF FVELFRMEQV
960 970 980 990 1000
RRIPEEYSLG RMVEGLSHRD PIMKVLSIRG LVILARRSEK MTKVQGLLPS
1010 1020 1030 1040 1050
MVKSLKNMDG VLVMEAVHDL KTIFKGQAKK LTDNSVYIEM LQTLLPHFID
1060 1070 1080 1090 1100
ARETVRTSCI NTYGKVVKKL RMPRTQAMEE QLTSTLMPLL FIIQEGNAKV
1110 1120
SQHFPLEFHT AGIFFLLVCR NV
Length:1,122
Mass (Da):123,859
Last modified:March 6, 2007 - v1
Checksum:i8BB49373A42A4BD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC133066 mRNA Translation: AAI33067.1
RefSeqiNP_001094435.1, NM_001100965.2
UniGeneiRn.61954

Genome annotation databases

EnsembliENSRNOT00000089934; ENSRNOP00000072770; ENSRNOG00000058870
GeneIDi298301
KEGGirno:298301
UCSCiRGD:1563440 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC133066 mRNA Translation: AAI33067.1
RefSeqiNP_001094435.1, NM_001100965.2
UniGeneiRn.61954

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiA2RUW0
PhosphoSitePlusiA2RUW0

Proteomic databases

PaxDbiA2RUW0
PRIDEiA2RUW0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000089934; ENSRNOP00000072770; ENSRNOG00000058870
GeneIDi298301
KEGGirno:298301
UCSCiRGD:1563440 rat

Organism-specific databases

CTDi374977
RGDi1563440 Mroh7

Phylogenomic databases

eggNOGiKOG2032 Eukaryota
ENOG410XQE8 LUCA
GeneTreeiENSGT00910000144041
HOVERGENiHBG107563
InParanoidiA2RUW0
OMAiGKDSGEM
OrthoDBiEOG091G00DQ
PhylomeDBiA2RUW0
TreeFamiTF337538

Miscellaneous databases

PROiPR:A2RUW0

Gene expression databases

BgeeiENSRNOG00000058870 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiA2RUW0 RN

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMROH7_RAT
AccessioniPrimary (citable) accession number: A2RUW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: March 6, 2007
Last modified: November 7, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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