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Protein

Protein FAM234B

Gene

FAM234B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM234B
Gene namesi
Name:FAM234BImported
Synonyms:KIAA1467
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000084444.13
HGNCiHGNC:29288 FAM234B
MIMi617837 gene
neXtProtiNX_A2RU67

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi57613
OpenTargetsiENSG00000084444
PharmGKBiPA128395790

Polymorphism and mutation databases

BioMutaiKIAA1467

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002889131 – 622Protein FAM234BAdd BLAST622

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei16PhosphoserineCombined sources1
Modified residuei26PhosphothreonineCombined sources1
Modified residuei30PhosphoserineCombined sources1
Modified residuei33PhosphoserineCombined sources1
Modified residuei62PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiA2RU67
MaxQBiA2RU67
PaxDbiA2RU67
PRIDEiA2RU67
ProteomicsDBi502

PTM databases

iPTMnetiA2RU67
PhosphoSitePlusiA2RU67

Expressioni

Gene expression databases

BgeeiENSG00000084444
CleanExiHS_KIAA1467
ExpressionAtlasiA2RU67 baseline and differential
GenevisibleiA2RU67 HS

Organism-specific databases

HPAiHPA010803
HPA010850

Interactioni

Protein-protein interaction databases

BioGridi121660, 51 interactors
IntActiA2RU67, 2 interactors
STRINGi9606.ENSP00000197268

Structurei

3D structure databases

ProteinModelPortaliA2RU67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM234 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IEKB Eukaryota
ENOG410YPIH LUCA
GeneTreeiENSGT00530000063694
HOGENOMiHOG000113167
HOVERGENiHBG101158
InParanoidiA2RU67
OMAiIFVQAQN
OrthoDBiEOG091G0JUN
PhylomeDBiA2RU67
TreeFamiTF327203

Family and domain databases

InterProiView protein in InterPro
IPR011047 Quinoprotein_ADH-like_supfam
SUPFAMiSSF50998 SSF50998, 3 hits

Sequencei

Sequence statusi: Complete.

A2RU67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATVLSRALK LPGKKSPDLG EYDPLTQADS DESEDDLVLN LQKNGGVKNG
60 70 80 90 100
KSPLGEAPEP DSDAEVAEAA KPHLSEVTTE GYPSEPLGGL EQKAASSLVS
110 120 130 140 150
YVRTSVFLLT LGISMILVLL CAFLIPCPPR DLHSTWSRHL GSQGGGDLSP
160 170 180 190 200
LELADVNGDG LRDVLLSFVM SRNGSAVGVS RPAANLVCLS GMNGSTLWSS
210 220 230 240 250
LLPEEARDIT CLELMPGSLA ETICLVTGTH KMLSAFNATS GKAIWTLNPN
260 270 280 290 300
YLSNGTLAAP VVVLPDLDED GVRDLVVLAI GELQPDLCFL LVSGRTGNPV
310 320 330 340 350
GRPVKYNIVG VGNLIGPQVY ITTNGAVYIL FGFGNIQAVA LRDIFVQAQN
360 370 380 390 400
RDSSPPSLQI EEPEWEKRRS INLSELIDVY SDGVELLQMV KAPDSNCSNL
410 420 430 440 450
LITTRQSLVL LRGQNLTPYW ALRLQGLRSQ PTPGYFTDDQ TLDFLLQIQD
460 470 480 490 500
GVGMKKMMVV DGDSGSIVWS YRAPCHMKET PATSAVTSDQ KSVFLFWAEG
510 520 530 540 550
LSAASPNSDI ILGTEPPSLH HLYLLHPAFP SILLDLANTT GTVTASEVGI
560 570 580 590 600
NDLWKDAFYV TRTTGPSSEG HPAALVVSKL SLRWALMEGQ MAQLQESTPK
610 620
IGRGELRRFL SRIKFVEAPY EI
Length:622
Mass (Da):67,039
Last modified:March 6, 2007 - v1
Checksum:i2C03F481C2FA7DC0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti59E → K in BAC86111 (PubMed:14702039).Curated1
Sequence conflicti91E → K in AAH39267 (PubMed:15489334).Curated1
Sequence conflicti189L → P in BAC86111 (PubMed:14702039).Curated1
Sequence conflicti450D → N in CAI56785 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125278 mRNA Translation: BAC86111.1
CR936647 mRNA Translation: CAI56785.1
BC039267 mRNA Translation: AAH39267.1
BC132772 mRNA Translation: AAI32773.1
BC132774 mRNA Translation: AAI32775.1
AB040900 mRNA Translation: BAA95991.1
CCDSiCCDS31750.1
RefSeqiNP_065904.1, NM_020853.1
UniGeneiHs.132660
Hs.712857

Genome annotation databases

EnsembliENST00000197268; ENSP00000197268; ENSG00000084444
ENST00000416494; ENSP00000394063; ENSG00000084444
GeneIDi57613
KEGGihsa:57613
UCSCiuc001rbi.4 human

Similar proteinsi

Entry informationi

Entry nameiF234B_HUMAN
AccessioniPrimary (citable) accession number: A2RU67
Secondary accession number(s): Q49AF2
, Q5CZ81, Q6ZUV7, Q9P261
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: March 6, 2007
Last modified: June 20, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

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