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Protein

Olfactory receptor

Gene

Olfr727

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr727Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:3030561 Olfr727

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 47HelicalUniRule annotationAdd BLAST22
Transmembranei59 – 78HelicalUniRule annotationAdd BLAST20
Transmembranei98 – 120HelicalUniRule annotationAdd BLAST23
Transmembranei140 – 162HelicalUniRule annotationAdd BLAST23
Transmembranei205 – 225HelicalUniRule annotationAdd BLAST21
Transmembranei237 – 260HelicalUniRule annotationAdd BLAST24
Transmembranei272 – 289HelicalUniRule annotationAdd BLAST18

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000059488 Expressed in 1 organ(s), highest expression level in brown adipose tissue

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078145

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 287G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST247

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IHJT Eukaryota
ENOG41113GX LUCA
GeneTreeiENSGT00900000140841
HOGENOMiHOG000041362
HOVERGENiHBG017625
KOiK04257
OMAiPKSMNET
OrthoDBiEOG091G0CY9
TreeFamiTF337251

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A2RTN7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNETNYSRVT EFVLLGLSSS KELQPFLFLI FSLLYLAILL GNFLIILTVT
60 70 80 90 100
SDSRLHTPMY FLLANLSFID MCVASFATPK MLADFLVERK TISFEACLAQ
110 120 130 140 150
IFFVHLFTGG EMVLLVSMAY DRYVAICKPL HYMTIMSRRV CIILVCISWF
160 170 180 190 200
VGFIHTTSQL AFTVNLPFCG PNKVDSFFCD LPLVTKLACI DTYVVSLLIV
210 220 230 240 250
ADSGFLSMSS FLLLVVSYTV ILITVRNRSS ASMAKARSTL TAHITVVVLF
260 270 280 290 300
FGPCIFIYVW PFSSYSVDKV LAVFYTIFTP ILNPVIYTLR NKEVKAAMSK
310 320
LRGRYLKPGQ VSALIRNVLF LETK
Length:324
Mass (Da):36,510
Last modified:March 6, 2007 - v1
Checksum:i659524092EC4BFD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140412 Genomic DNA No translation available.
BC132575 mRNA Translation: AAI32576.1
BC145712 mRNA Translation: AAI45713.1
RefSeqiNP_666431.2, NM_146319.2
UniGeneiMm.223012

Genome annotation databases

EnsembliENSMUST00000079142; ENSMUSP00000078145; ENSMUSG00000059488
ENSMUST00000215317; ENSMUSP00000149886; ENSMUSG00000059488
GeneIDi258316
KEGGimmu:258316
UCSCiuc007tkq.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140412 Genomic DNA No translation available.
BC132575 mRNA Translation: AAI32576.1
BC145712 mRNA Translation: AAI45713.1
RefSeqiNP_666431.2, NM_146319.2
UniGeneiMm.223012

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000078145

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000079142; ENSMUSP00000078145; ENSMUSG00000059488
ENSMUST00000215317; ENSMUSP00000149886; ENSMUSG00000059488
GeneIDi258316
KEGGimmu:258316
UCSCiuc007tkq.2 mouse

Organism-specific databases

CTDi258316
MGIiMGI:3030561 Olfr727

Phylogenomic databases

eggNOGiENOG410IHJT Eukaryota
ENOG41113GX LUCA
GeneTreeiENSGT00900000140841
HOGENOMiHOG000041362
HOVERGENiHBG017625
KOiK04257
OMAiPKSMNET
OrthoDBiEOG091G0CY9
TreeFamiTF337251

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000059488 Expressed in 1 organ(s), highest expression level in brown adipose tissue

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2RTN7_MOUSE
AccessioniPrimary (citable) accession number: A2RTN7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: September 12, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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