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UniProtKB - A2RTF1 (CTSRB_MOUSE)

Entry version 84 (13 Feb 2019)
Sequence version 1 (06 Mar 2007)
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Protein

Cation channel sperm-associated protein subunit beta

Gene

Catsperb

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.1 Publication

Miscellaneous

CatSperb is absent in sperm from mice lacking CatSper1, suggesting that stable expression of CatSperb protein requires CatSper1.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • multicellular organism development Source: UniProtKB-KW
  • sperm capacitation Source: MGI
View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Spermatogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-1300642 Sperm Motility And Taxes

Protein family/group databases

Transport Classification Database

More...TCDBi		1.A.1.19.3 the voltage-gated ion channel (vic) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cation channel sperm-associated protein subunit beta
Short name:
CatSper-beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Catsperb
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2443988 Catsperb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei1060 – 1080HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002957031 – 1109Cation channel sperm-associated protein subunit betaAdd BLAST1109

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi321N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi672N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi915N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1017N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A2RTF1

PRoteomics IDEntifications database

More...PRIDEi		A2RTF1

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A2RTF1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis-specific. Specifically present in the principal piece of sperm tail (at protein level). Specifically expressed in the seminiferous tubules but not in the interstitial cells. Within the tubules, it is expressed in spermatocytes and spermatids, but not in spermatogonia.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000047014 Expressed in 6 organ(s), highest expression level in spermatid

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A2RTF1 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the CatSper complex.3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		234824, 1 interactor

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		A2RTF1

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000052089

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		A2RTF1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A2RTF1

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IH6R Eukaryota
ENOG4111J8A LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000008198

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000112054

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG101990

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A2RTF1

KEGG Orthology (KO)

More...KOi		K16893

Identification of Orthologs from Complete Genome Data

More...OMAi		KEPFLEW

Database of Orthologous Groups

More...OrthoDBi		846266at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A2RTF1

TreeFam database of animal gene trees

More...TreeFami		TF328432

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR028748 CATSPERB

The PANTHER Classification System

More...PANTHERi		PTHR14705 PTHR14705, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15149 CATSPERB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A2RTF1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESPLIYVML VLLNVFVFSS GVIHNKGKER TYFSCSGEGI LTGLHTIKLF 
        60         70         80         90        100
LTMDNLKVRC FFRNENQSPS KEILGLFTSG GLAPNMIITN STFYGGYYFK 
       110        120        130        140        150
LTPFSNRLEW LIDIPRQNIT VNTDIAAVEQ WMIKITMHEG LNIYDTEGTL 
       160        170        180        190        200
LDLVREPILQ WNLGRVLTEM EVRDLYPEVN DIKVTKSPCA NDVALIGFMM 
       210        220        230        240        250
KPSSNGVFIG KTISGFWTYK ECIWHDLTEI IYAELKDEHQ GLTVIDLVLT 
       260        270        280        290        300
NHFLVILTSL GLYVSSDLRY PTTSQIKLSR AEFCGFERVD YIRGNLWYNE 
       310        320        330        340        350
KCFANRESFE VDYVTITFNR NRTLSESSSC FFSKEPFLHW LPCVFSTIKN 
       360        370        380        390        400
EKSIPRVITF LIDQETDSGI YLFNVQDTKE TYVTVAMLKD GKPSPRPKFP 
       410        420        430        440        450
SFHFPSTFTL PLGMIFHPRS HFLYVYGSQI WVSMDGGNTF EMLCNLFSHH 
       460        470        480        490        500
VTKTSNSFYT SDIVFIVEDG RILTTKAGLT TYSELGILKD AIFTLYYDQL 
       510        520        530        540        550
GYIHKLTPEN FDAGSKLLGH GNSGSIFGKR PDLGFEAILV PQYISTNEMY 
       560        570        580        590        600
FFAHVPLTMP TNIQWKKRFK TIHLGKTIEF SKTGLANIKN VYMHKTEPVG 
       610        620        630        640        650
FQTSIHTEII VPFGIENSKD SPCLLSDLEI TYSGKLYYTI KLLSKNPLHE 
       660        670        680        690        700
LKSTDVEKSV LIPGYSSFLI MNITDKWTAS ALATMPQAIK SNLKFLTGSW 
       710        720        730        740        750
FLYNFGTAGG RKWSISTRQC NYWIQQDSLD FMSLNLVKYI DVGNTIDFQF 
       760        770        780        790        800
KIIPKAMSTF PIPPVSMVVG NPGLVEVKTQ GVFDLNENYY LDIHVSGRFF 
       810        820        830        840        850
QKGSTSIALV LWEGSSKCYA ITLLPTIKSS CSYLRTMHHT PGRHIPPEDW 
       860        870        880        890        900
ISGVHKDSQG FNMIKTLPIN YRPPSHMGIS IPLTDNFYHA DPSKPIPRNQ 
       910        920        930        940        950
FHKSKETGKY KQCANVTSRA MCNCSEHQKF SHAVAFSDCK EKVHRFKFPV 
       960        970        980        990       1000
TQYPVVLEIF NERDKISAEP PYLVTMTEVN MRKNWQLKHN EPENVKKMKH 
      1010       1020       1030       1040       1050
YLEPLLKTPV YNPLGLNLTI QGSELFHFKV SVVPGVSFCE LSEEFQIYVD 
      1060       1070       1080       1090       1100
EVPLPFPGHA LIAVATSVVL GVLIFIAFVF QLRNIHPLKA LKKSIRGNPG 

LTSSTTVSS
Length:1,109
Mass (Da):126,108
Last modified:March 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i411A5261B70CED5B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VNW5A0A1Y7VNW5_MOUSE
Cation channel sperm-associated pro...
Catsperb
430Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VLR9A0A1Y7VLR9_MOUSE
Cation channel sperm-associated pro...
Catsperb
33Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti792D → G in BAC26731 (PubMed:16141072).Curated1
Sequence conflicti1013P → T in BAC26731 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
EF199807 mRNA Translation: ABO93459.1
AK030010 mRNA Translation: BAC26731.1
BC132479 mRNA Translation: AAI32480.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS26112.1

NCBI Reference Sequences

More...RefSeqi		NP_766611.2, NM_173023.2

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Mm.84218

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000055156; ENSMUSP00000052089; ENSMUSG00000047014

Database of genes from NCBI RefSeq genomes

More...GeneIDi		271036

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:271036

UCSC genome browser

More...UCSCi		uc007otl.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF199807 mRNA Translation: ABO93459.1
AK030010 mRNA Translation: BAC26731.1
BC132479 mRNA Translation: AAI32480.1
CCDSiCCDS26112.1
RefSeqiNP_766611.2, NM_173023.2
UniGeneiMm.84218

3D structure databases

ProteinModelPortaliA2RTF1
SMRiA2RTF1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi234824, 1 interactor
CORUMiA2RTF1
STRINGi10090.ENSMUSP00000052089

Protein family/group databases

TCDBi1.A.1.19.3 the voltage-gated ion channel (vic) superfamily

PTM databases

PhosphoSitePlusiA2RTF1

Proteomic databases

PaxDbiA2RTF1
PRIDEiA2RTF1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000055156; ENSMUSP00000052089; ENSMUSG00000047014
GeneIDi271036
KEGGimmu:271036
UCSCiuc007otl.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79820
MGIiMGI:2443988 Catsperb

Phylogenomic databases

eggNOGiENOG410IH6R Eukaryota
ENOG4111J8A LUCA
GeneTreeiENSGT00390000008198
HOGENOMiHOG000112054
HOVERGENiHBG101990
InParanoidiA2RTF1
KOiK16893
OMAiKEPFLEW
OrthoDBi846266at2759
PhylomeDBiA2RTF1
TreeFamiTF328432

Enzyme and pathway databases

ReactomeiR-MMU-1300642 Sperm Motility And Taxes

Miscellaneous databases

Protein Ontology

More...PROi		PR:A2RTF1

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000047014 Expressed in 6 organ(s), highest expression level in spermatid
ExpressionAtlasiA2RTF1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR028748 CATSPERB
PANTHERiPTHR14705 PTHR14705, 1 hit
PfamiView protein in Pfam
PF15149 CATSPERB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTSRB_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2RTF1
Secondary accession number(s): Q8C0R2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 6, 2007
Last modified: February 13, 2019
This is version 84 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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