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Protein

Beta-galactosidase-1-like protein 3

Gene

Glb1l3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei203Proton donorBy similarity1
Active sitei277NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiGH35 Glycoside Hydrolase Family 35

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase-1-like protein 3 (EC:3.2.1.-)
Gene namesi
Name:Glb1l3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1918143 Glb1l3

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002830291 – 649Beta-galactosidase-1-like protein 3Add BLAST649

Proteomic databases

PaxDbiA2RSQ1
PRIDEiA2RSQ1

PTM databases

iPTMnetiA2RSQ1
PhosphoSitePlusiA2RSQ1

Expressioni

Gene expression databases

CleanExiMM_GLB1L3

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034448

Structurei

3D structure databases

ProteinModelPortaliA2RSQ1
SMRiA2RSQ1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 35 family.Curated

Phylogenomic databases

eggNOGiKOG0496 Eukaryota
COG1874 LUCA
HOGENOMiHOG000221607
HOVERGENiHBG004841
InParanoidiA2RSQ1
PhylomeDBiA2RSQ1

Family and domain databases

Gene3Di2.60.120.260, 3 hits
InterProiView protein in InterPro
IPR026283 B-gal_1-like
IPR008979 Galactose-bd-like_sf
IPR031330 Gly_Hdrlase_35_cat
IPR019801 Glyco_hydro_35_CS
IPR001944 Glycoside_Hdrlase_35
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR23421 PTHR23421, 1 hit
PfamiView protein in Pfam
PF01301 Glyco_hydro_35, 1 hit
PIRSFiPIRSF006336 B-gal, 1 hit
PRINTSiPR00742 GLHYDRLASE35
SUPFAMiSSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS01182 GLYCOSYL_HYDROL_F35, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A2RSQ1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAIFFLPTVL SGFAPHSEEV FKSPARFSWS NLTPSELKNR FVGLSTKTNA
60 70 80 90 100
LGKAYFTLEG HKFMIVGGSI HYFRVPREYW KDRLLKLQAC GFNTVTTYIP
110 120 130 140 150
WNLHEQERGK FDFSEILDLE AYVLLAKTIG LWVILRPGPY ICAEVDLGGL
160 170 180 190 200
PSWLLRNPVT DLRTTNKGFI EAVDKYFDHL IPKILPLQYR HGGPVIAVQV
210 220 230 240 250
ENEYGSFQKD RNYMNYLKKA LLKRGIVELL LTSDDKDGIQ IGSVNGALTT
260 270 280 290 300
INMNSFTKDS FIKLHKMQSD KPIMIMEYWT GWYDSWGSKH IEKSAEEIRH
310 320 330 340 350
TVYKFISYGL SFNMYMFHGG TNFGFINGGR YENHHISVVT SYDYDAVLSE
360 370 380 390 400
AGDYTEKYFK LRKLFASGSA RPLPPLPPLI PKAIYPSVNL SFYLPLFDIL
410 420 430 440 450
PYLNQPVMLH TPVTMENLPI NNGSGQPFGL VLYETSICSG GSLFASVHDS
460 470 480 490 500
AQVFLNDQSI GILDENHEVL QIPKIQGCQL LRILVENQGR INYSWRIQSE
510 520 530 540 550
QKGLKEVVSI DGLLLTNFTI YSLDMKMSFF KRLRSASWRL APKTYNGPAF
560 570 580 590 600
YWGILNAGSS PTDTFLHLPN WHYGFVFING RNLGRYWDIG PQRTLYLPGP
610 620 630 640
WLHPEDNEVI VFEKIEKGFD IQTRKKPQLQ ECYETGSGLP DAAGDADPC
Length:649
Mass (Da):73,922
Last modified:March 6, 2007 - v1
Checksum:iD1DDD9444628C747
GO
Isoform 2 (identifier: A2RSQ1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-63: Missing.

Show »
Length:586
Mass (Da):66,888
Checksum:i27C625BEF617AADC
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GSK9A0A1B0GSK9_MOUSE
Beta-galactosidase
Glb1l3
662Annotation score:
F8WIH9F8WIH9_MOUSE
Beta-galactosidase-1-like protein 3
Glb1l3
587Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0242891 – 63Missing in isoform 2. 1 PublicationAdd BLAST63

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014852 mRNA Translation: BAB29584.1
BC132200 mRNA Translation: AAI32201.1
BC132202 mRNA Translation: AAI32203.1
RefSeqiNP_001106794.1, NM_001113323.1
UniGeneiMm.78118

Genome annotation databases

GeneIDi70893
KEGGimmu:70893
UCSCiuc009opw.2 mouse [A2RSQ1-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014852 mRNA Translation: BAB29584.1
BC132200 mRNA Translation: AAI32201.1
BC132202 mRNA Translation: AAI32203.1
RefSeqiNP_001106794.1, NM_001113323.1
UniGeneiMm.78118

3D structure databases

ProteinModelPortaliA2RSQ1
SMRiA2RSQ1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034448

Protein family/group databases

CAZyiGH35 Glycoside Hydrolase Family 35

PTM databases

iPTMnetiA2RSQ1
PhosphoSitePlusiA2RSQ1

Proteomic databases

PaxDbiA2RSQ1
PRIDEiA2RSQ1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi70893
KEGGimmu:70893
UCSCiuc009opw.2 mouse [A2RSQ1-1]

Organism-specific databases

CTDi112937
MGIiMGI:1918143 Glb1l3

Phylogenomic databases

eggNOGiKOG0496 Eukaryota
COG1874 LUCA
HOGENOMiHOG000221607
HOVERGENiHBG004841
InParanoidiA2RSQ1
PhylomeDBiA2RSQ1

Miscellaneous databases

PROiPR:A2RSQ1
SOURCEiSearch...

Gene expression databases

CleanExiMM_GLB1L3

Family and domain databases

Gene3Di2.60.120.260, 3 hits
InterProiView protein in InterPro
IPR026283 B-gal_1-like
IPR008979 Galactose-bd-like_sf
IPR031330 Gly_Hdrlase_35_cat
IPR019801 Glyco_hydro_35_CS
IPR001944 Glycoside_Hdrlase_35
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR23421 PTHR23421, 1 hit
PfamiView protein in Pfam
PF01301 Glyco_hydro_35, 1 hit
PIRSFiPIRSF006336 B-gal, 1 hit
PRINTSiPR00742 GLHYDRLASE35
SUPFAMiSSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS01182 GLYCOSYL_HYDROL_F35, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLBL3_MOUSE
AccessioniPrimary (citable) accession number: A2RSQ1
Secondary accession number(s): Q9D5X3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: March 6, 2007
Last modified: February 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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