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Entry version 98 (16 Jan 2019)
Sequence version 2 (08 Apr 2008)
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Protein

DENN domain-containing protein 5B

Gene

Dennd5b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DENN domain-containing protein 5B
Alternative name(s):
Rab6IP1-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dennd5b
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444273 Dennd5b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei916 – 936HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003265322 – 1274DENN domain-containing protein 5BAdd BLAST1273

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
Modified residuei49PhosphoserineCombined sources1
Modified residuei178PhosphoserineCombined sources1
Modified residuei822PhosphoserineBy similarity1
Modified residuei1062PhosphothreonineBy similarity1
Modified residuei1068PhosphoserineBy similarity1
Modified residuei1076PhosphoserineBy similarity1
Modified residuei1079PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A2RSQ0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2RSQ0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A2RSQ0

PeptideAtlas

More...
PeptideAtlasi
A2RSQ0

PRoteomics IDEntifications database

More...
PRIDEi
A2RSQ0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2RSQ0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A2RSQ0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030313 Expressed in 238 organ(s), highest expression level in cerebellum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2RSQ0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2RSQ0 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000107182

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A2RSQ0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2RSQ0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 244uDENNPROSITE-ProRule annotationAdd BLAST206
Domaini263 – 399cDENNPROSITE-ProRule annotationAdd BLAST137
Domaini401 – 581dDENNPROSITE-ProRule annotationAdd BLAST181
Domaini772 – 932RUN 1PROSITE-ProRule annotationAdd BLAST161
Domaini936 – 1044PLATPROSITE-ProRule annotationAdd BLAST109
Domaini1118 – 1267RUN 2PROSITE-ProRule annotationAdd BLAST150

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RAB6IP1 family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2080 Eukaryota
ENOG410XNYP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153678

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000019389

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG059906

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2RSQ0

KEGG Orthology (KO)

More...
KOi
K20164

Identification of Orthologs from Complete Genome Data

More...
OMAi
LGKQCRT

Database of Orthologous Groups

More...
OrthoDBi
53600at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2RSQ0

TreeFam database of animal gene trees

More...
TreeFami
TF313237

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR001024 PLAT/LH2_dom
IPR036392 PLAT/LH2_dom_sf
IPR004012 Run_dom
IPR037213 Run_dom_sf
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03455 dDENN, 1 hit
PF02141 DENN, 1 hit
PF01477 PLAT, 1 hit
PF02759 RUN, 2 hits
PF03456 uDENN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00593 RUN, 2 hits
SM00800 uDENN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF140741 SSF140741, 2 hits
SSF49723 SSF49723, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50211 DENN, 1 hit
PS50095 PLAT, 1 hit
PS50826 RUN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A2RSQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGSSAAPGP GSGSSPAACR FAHYFVLCGI DADSGLEPDE LAGENFDQSP
60 70 80 90 100
LRRTFKSKVL AHYPQNIEWN PFDQDAVNML CMPKGLSFRT QADNKEPQFH
110 120 130 140 150
SFIITREDGS RTYGFVLTFY EEVTSKQICT AMQTLYQMHN AEQYSSVYAS
160 170 180 190 200
SSCSMDSLAS SIDEGDATSL LKLQRYNSYD INRDTLYVSK SICLITPLPF
210 220 230 240 250
MQACKKFLFQ LHKAVTSQQP PPLPLESYIH NILYEVPLPP PGRSLKFYGV
260 270 280 290 300
YEPVICQRPG PNELPLSDYP LREACELLGL ENLVQVFTCV LLEMQTLLYS
310 320 330 340 350
QDYQRLMTVA EGITTLLFPF QWQHVYVPIL PASLLHFLDA PVPYLMGLQS
360 370 380 390 400
KEGTDRSKLE LPQEANLCFV DIDNHFIELP EEFPQFPNKV DFIQELSEVL
410 420 430 440 450
LQFGIPPEGS LHSSESATKL KNMVLKDLAN DKKNGNVPNN SVSVYELLKG
460 470 480 490 500
SETIARLQAL AKRTGVTMEK IDLPASLSEK EKDLKLQCEE ADLRDSQLNV
510 520 530 540 550
QLREVFANRF TQMFADYEAF VIQTAQDMES WLTNREQMQN FDKASFLSDQ
560 570 580 590 600
PEPYLPFLSR FIETQMFATF IDNKIMSQWE EKDPLLRVFD SRIEKIRLYN
610 620 630 640 650
VRAPTLRTSI YQKCSSLKEA AQSIEQRLMK MDHTAIHPHL LDMKIGQGKY
660 670 680 690 700
EQGFFPKLQS DVLATGPANN NRWVSRSATA QRRKERLRQS SEHIGLDSDL
710 720 730 740 750
REKYMQEARS LGKNLRQPKL SDLSPAVIAQ TNWKFVEGLL KECRMKTKRM
760 770 780 790 800
LVEKMGHEAV ELGHGEANIT GLEENTLIAS LCDLLERIWS HGLLVKQGKS
810 820 830 840 850
ALWSHLLQFQ DREEKQEHLT DSPVALGPER RKSDSGVMLP TLRVSLIQDM
860 870 880 890 900
RHIQNMTEIK TDVGRARAWI RLSLEKKLLS QHLKQLLSNQ PLTKKLYKRY
910 920 930 940 950
AFLRCEEERE QFLYHLLSLN AVDYFCFTSV FTTIMIPYRS VIIPIKKLSN
960 970 980 990 1000
AIITSNPWIC VSGELGDTGV MQIPKNLLEM TFECQNLGKL TTVQIGHDNS
1010 1020 1030 1040 1050
GLLAKWLVDC VMVRNEITGH TYRFPCGRWL GKGVDDGSLE RILIGELMTS
1060 1070 1080 1090 1100
ASDEDLGKQC RTPPQQKSPT TTRRLSITSL TGKPAKPNAG QIQEGIGEAV
1110 1120 1130 1140 1150
NNIVKHFHKP EKERGSLTVL LCGENGLVAA LEQVFHHGFK SARIFHKNVF
1160 1170 1180 1190 1200
IWDFVEKAVA YFETTDQILD NEGDVLIQKP SSKTFCHYVN AINTAPRNIG
1210 1220 1230 1240 1250
KDGKFQILVC LGTRDHLLPQ WIPLLAECPA ITRMYEENAL LRDHMTVNSL
1260 1270
IRILQTIQDF TIVLEGSLIK GVDV
Length:1,274
Mass (Da):144,629
Last modified:April 8, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA29B06B3AB9FC946
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B8JKU3B8JKU3_MOUSE
DENN domain-containing protein 5B
Dennd5b
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q0R9E9Q0R9_MOUSE
DENN domain-containing protein 5B
Dennd5b
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI32200 differs from that shown. Probable cloning artifact.Curated
The sequence AAI32536 differs from that shown. Probable cloning artifact.Curated
The sequence BAC34394 differs from that shown. Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti37E → G in BAC34394 (PubMed:16141072).Curated1
Sequence conflicti83P → R in BAC34923 (PubMed:16141072).Curated1
Sequence conflicti153C → S in BAC34923 (PubMed:16141072).Curated1
Sequence conflicti221P → Q in BAC34923 (PubMed:16141072).Curated1
Sequence conflicti225L → H in BAC34394 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC132412 Genomic DNA No translation available.
AC140327 Genomic DNA No translation available.
AK050728 mRNA Translation: BAC34394.1 Sequence problems.
AK052296 mRNA Translation: BAC34923.1
BC132199 mRNA Translation: AAI32200.1 Sequence problems.
BC132535 mRNA Translation: AAI32536.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20714.2

NCBI Reference Sequences

More...
RefSeqi
NP_796166.2, NM_177192.3

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.426874

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000111557; ENSMUSP00000107182; ENSMUSG00000030313

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
320560

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:320560

UCSC genome browser

More...
UCSCi
uc009ett.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132412 Genomic DNA No translation available.
AC140327 Genomic DNA No translation available.
AK050728 mRNA Translation: BAC34394.1 Sequence problems.
AK052296 mRNA Translation: BAC34923.1
BC132199 mRNA Translation: AAI32200.1 Sequence problems.
BC132535 mRNA Translation: AAI32536.1 Sequence problems.
CCDSiCCDS20714.2
RefSeqiNP_796166.2, NM_177192.3
UniGeneiMm.426874

3D structure databases

ProteinModelPortaliA2RSQ0
SMRiA2RSQ0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000107182

PTM databases

iPTMnetiA2RSQ0
PhosphoSitePlusiA2RSQ0

Proteomic databases

jPOSTiA2RSQ0
MaxQBiA2RSQ0
PaxDbiA2RSQ0
PeptideAtlasiA2RSQ0
PRIDEiA2RSQ0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111557; ENSMUSP00000107182; ENSMUSG00000030313
GeneIDi320560
KEGGimmu:320560
UCSCiuc009ett.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
160518
MGIiMGI:2444273 Dennd5b

Phylogenomic databases

eggNOGiKOG2080 Eukaryota
ENOG410XNYP LUCA
GeneTreeiENSGT00940000153678
HOGENOMiHOG000019389
HOVERGENiHBG059906
InParanoidiA2RSQ0
KOiK20164
OMAiLGKQCRT
OrthoDBi53600at2759
PhylomeDBiA2RSQ0
TreeFamiTF313237

Enzyme and pathway databases

ReactomeiR-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A2RSQ0

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030313 Expressed in 238 organ(s), highest expression level in cerebellum
ExpressionAtlasiA2RSQ0 baseline and differential
GenevisibleiA2RSQ0 MM

Family and domain databases

InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR001024 PLAT/LH2_dom
IPR036392 PLAT/LH2_dom_sf
IPR004012 Run_dom
IPR037213 Run_dom_sf
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom
PfamiView protein in Pfam
PF03455 dDENN, 1 hit
PF02141 DENN, 1 hit
PF01477 PLAT, 1 hit
PF02759 RUN, 2 hits
PF03456 uDENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00593 RUN, 2 hits
SM00800 uDENN, 1 hit
SUPFAMiSSF140741 SSF140741, 2 hits
SSF49723 SSF49723, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit
PS50095 PLAT, 1 hit
PS50826 RUN, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDEN5B_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2RSQ0
Secondary accession number(s): Q8BII7, Q8BWK2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: April 8, 2008
Last modified: January 16, 2019
This is version 98 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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