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UniProtKB - A2RRD8 (ZN320_HUMAN)

Entry version 119 (02 Dec 2020)
Sequence version 1 (06 Mar 2007)
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Protein

Zinc finger protein 320

Gene

ZNF320

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri161 – 183C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri217 – 239C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri245 – 267C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri273 – 295C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri301 – 323C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri329 – 351C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri357 – 379C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri385 – 407C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 12; degeneratePROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		A2RRD8

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 320
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF320
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000182986.12

Human Gene Nomenclature Database

More...HGNCi		HGNC:13842, ZNF320

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		606427, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_A2RRD8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving ZNF320 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with BRWD2/WDR11.1 Publication

Keywords - Diseasei

Proto-oncogene

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000182986

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37819

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		A2RRD8, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF320

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003002631 – 509Zinc finger protein 320Add BLAST509

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		A2RRD8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		A2RRD8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		A2RRD8

MaxQB - The MaxQuant DataBase

More...MaxQBi		A2RRD8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A2RRD8

PeptideAtlas

More...PeptideAtlasi		A2RRD8

PRoteomics IDEntifications database

More...PRIDEi		A2RRD8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		462

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		A2RRD8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A2RRD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at high levels in placenta, pancreas, kidney and heart, and at lower levels in liver, skeletal muscle and brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000182986, Expressed in buccal mucosa cell and 208 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A2RRD8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A2RRD8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000182986, Low tissue specificity
ENSG00000204604, Tissue enhanced (placenta)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127834, 6 interactors

Protein interaction database and analysis system

More...IntActi		A2RRD8, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000473091

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		A2RRD8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A2RRD8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 80KRABPROSITE-ProRule annotationAdd BLAST73

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri161 – 183C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri189 – 211C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri217 – 239C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri245 – 267C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri273 – 295C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri301 – 323C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri329 – 351C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri357 – 379C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri385 – 407C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 12; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000163506

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A2RRD8

Identification of Orthologs from Complete Genome Data

More...OMAi		YHIGALC

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A2RRD8

TreeFam database of animal gene trees

More...TreeFami		TF341892

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A2RRD8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS 
        60         70         80         90        100
SKCMMNTLSS TGQGNTEVIH TGTLQRQASY HIGAFCSQEI EKDIHDFVFQ 
       110        120        130        140        150
WQEDETNDHE APMTEIKKLT SSTDRYDQRH AGNKPIKGQL ESRFHLHLRR 
       160        170        180        190        200
HRRIHTGEKP YKCEECEKVF SCKSHLEIHR IIHTGEKPYK CKVCDKAFKH 
       210        220        230        240        250
DSHLAKHTRI HRGDKHYTCN ECGKVFDQKA TLACHHRSHT GEKPYKCNEC 
       260        270        280        290        300
GKTFSQTSHL VYHHRLHTGE KPYKCNECGK TFARNSVLVI HKAVHTAEKP 
       310        320        330        340        350
YKCNECGKVF KQRATLAGHR RVHTGEKPYR CEECDKVFSR KSHLERHRRI 
       360        370        380        390        400
HTGEKPYKCK VCDKAFRSDS RLAEHQRVHT GERPYTCNEC GKVFSTKAYL 
       410        420        430        440        450
ACHQKLHTGE KLYECEECDK VYIRKSHLER HRRIHTGEKP HKCGDCGKAF 
       460        470        480        490        500
NSPSHLIRHQ RIHTGQKSYK CHQCGKVFSL RSLLAEHQKI PFGDNCFKCN 

EYSKPSSIN
Length:509
Mass (Da):59,326
Last modified:March 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D221BC43C684B61
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QX96M0QX96_HUMAN
Zinc finger protein 320
ZNF320
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZA2M0QZA2_HUMAN
Zinc finger protein 320
ZNF320
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1K6M0R1K6_HUMAN
Zinc finger protein 320
ZNF320
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R2L4M0R2L4_HUMAN
Zinc finger protein 320
ZNF320
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0Z8M0R0Z8_HUMAN
Zinc finger protein 320
ZNF320
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A669KBJ2A0A669KBJ2_HUMAN
Zinc finger protein 320
ZNF320
117Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC131555 mRNA Translation: AAI31556.1
AL831902 mRNA Translation: CAD38570.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS33095.1

NCBI Reference Sequences

More...RefSeqi		NP_997216.2, NM_207333.2
XP_006723122.1, XM_006723059.3
XP_016881882.1, XM_017026393.1
XP_016881883.1, XM_017026394.1
XP_016881884.1, XM_017026395.1
XP_016881885.1, XM_017026396.1
XP_016881886.1, XM_017026397.1
XP_016881887.1, XM_017026398.1
XP_016881888.1, XM_017026399.1
XP_016881889.1, XM_017026400.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000391781; ENSP00000375660; ENSG00000182986
ENST00000595635; ENSP00000473091; ENSG00000182986

Database of genes from NCBI RefSeq genomes

More...GeneIDi		162967

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:162967

UCSC genome browser

More...UCSCi		uc002qai.4, human

Keywords - Coding sequence diversityi

Chromosomal rearrangement

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC131555 mRNA Translation: AAI31556.1
AL831902 mRNA Translation: CAD38570.1
CCDSiCCDS33095.1
RefSeqiNP_997216.2, NM_207333.2
XP_006723122.1, XM_006723059.3
XP_016881882.1, XM_017026393.1
XP_016881883.1, XM_017026394.1
XP_016881884.1, XM_017026395.1
XP_016881885.1, XM_017026396.1
XP_016881886.1, XM_017026397.1
XP_016881887.1, XM_017026398.1
XP_016881888.1, XM_017026399.1
XP_016881889.1, XM_017026400.1

3D structure databases

SMRiA2RRD8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127834, 6 interactors
IntActiA2RRD8, 3 interactors
STRINGi9606.ENSP00000473091

PTM databases

iPTMnetiA2RRD8
PhosphoSitePlusiA2RRD8

Polymorphism and mutation databases

BioMutaiZNF320

Proteomic databases

EPDiA2RRD8
jPOSTiA2RRD8
MassIVEiA2RRD8
MaxQBiA2RRD8
PaxDbiA2RRD8
PeptideAtlasiA2RRD8
PRIDEiA2RRD8
ProteomicsDBi462

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		46227, 40 antibodies

Genome annotation databases

EnsembliENST00000391781; ENSP00000375660; ENSG00000182986
ENST00000595635; ENSP00000473091; ENSG00000182986
GeneIDi162967
KEGGihsa:162967
UCSCiuc002qai.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		162967
EuPathDBiHostDB:ENSG00000182986.12

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF320
HGNCiHGNC:13842, ZNF320
HPAiENSG00000182986, Low tissue specificity
ENSG00000204604, Tissue enhanced (placenta)
MIMi606427, gene
neXtProtiNX_A2RRD8
OpenTargetsiENSG00000182986
PharmGKBiPA37819

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000163506
HOGENOMiCLU_002678_0_2_1
InParanoidiA2RRD8
OMAiYHIGALC
OrthoDBi1318335at2759
PhylomeDBiA2RRD8
TreeFamiTF341892

Enzyme and pathway databases

PathwayCommonsiA2RRD8
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		162967, 37 hits in 862 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF320, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		162967
PharosiA2RRD8, Tdark

Protein Ontology

More...PROi		PR:A2RRD8
RNActiA2RRD8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000182986, Expressed in buccal mucosa cell and 208 other tissues
ExpressionAtlasiA2RRD8, baseline and differential
GenevisibleiA2RRD8, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN320_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2RRD8
Secondary accession number(s): Q8NDR6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 6, 2007
Last modified: December 2, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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