Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Lactococcus lactis subsp. cremoris (strain MG1363)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:llmg_1982
OrganismiLactococcus lactis subsp. cremoris (strain MG1363)
Taxonomic identifieri416870 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000000364 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003003351 – 1196DNA-directed RNA polymerase subunit betaAdd BLAST1196

Proteomic databases

PRIDEiA2RML9

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi416870.llmg_1982

Structurei

3D structure databases

ProteinModelPortaliA2RML9
SMRiA2RML9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ Bacteria
COG0085 LUCA
HOGENOMiHOG000218611
KOiK03043
OMAiFMTWEGY

Family and domain databases

CDDicd00653 RNA_pol_B_RPB2, 1 hit
Gene3Di2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit
HAMAPiMF_01321 RNApol_bact_RpoB, 1 hit
InterProiView protein in InterPro
IPR019462 DNA-dir_RNA_pol_bsu_external_1
IPR015712 DNA-dir_RNA_pol_su2
IPR007120 DNA-dir_RNAP_su2_dom
IPR037033 DNA-dir_RNAP_su2_hyb_sf
IPR010243 RNA_pol_bsu_bac
IPR007121 RNA_pol_bsu_CS
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
IPR007645 RNA_pol_Rpb2_3
IPR007641 RNA_pol_Rpb2_7
IPR014724 RNA_pol_RPB2_OB-fold
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 2 hits
PF04565 RNA_pol_Rpb2_3, 1 hit
PF10385 RNA_pol_Rpb2_45, 1 hit
PF00562 RNA_pol_Rpb2_6, 1 hit
PF04560 RNA_pol_Rpb2_7, 1 hit
TIGRFAMsiTIGR02013 rpoB, 1 hit
PROSITEiView protein in PROSITE
PS01166 RNA_POL_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

A2RML9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGHDVKYGK HRTRRSFSRI KEVIGLPNLI EVQTLSYKNF LDEGLANVFK
60 70 80 90 100
EMFPIDNFAG TMELEFVGYE MKTPKYTVEE ARAHDANYSA PIYVTFRLVN
110 120 130 140 150
KETGELKTQE VFFGDFPLMT EMGTFINNGS ERLIVSQLVR SPGSYFHLKT
160 170 180 190 200
DKNGLESFGH TTIPNRGAWF ELDTDAKGIG YVRIDRTRKL TFTTMLRALG
210 220 230 240 250
FGSDDEILEL LGETQLLTDT IAKDVHKNPA DTRVEEALKD IYDRLRPGEP
260 270 280 290 300
KTADSSRGLL VARFFDPKRY DFAPVGRYKF NKKLALKNRL LGLTLAEPIV
310 320 330 340 350
DPETGEILVN TDTLVTRDVL DLIEPLLDNG LGNFVVEPSD DAVIPEPITL
360 370 380 390 400
QSIKVYSPKD SERVVTLLSN GNPDSECRVL TPADVISNIS YWLGLAEGIG
410 420 430 440 450
KVDDIDHLGN RRIRSVGELL QNQVRIGLSR MERVIRERMS SSENENITPQ
460 470 480 490 500
GLINIRPVTA SIKEFFGSSQ LSQFMDQHNP LSELSHKRRF SALGPGGISR
510 520 530 540 550
DRASYEVRDV HYTHYGRMCP IETPEGPNIG LINNLSSYAK VNEYGFIMSP
560 570 580 590 600
YRRVDRVNGI VTDEVEYLTA DEEDNYTVAQ ANSPLTDDSR FANETVMARH
610 620 630 640 650
TGNNIEVEAS TADYMDVSPK QVIAVAAACI PFLENDDSNR ALMGANMQRQ
660 670 680 690 700
AVPLIDPHAP WIGTGMEHQT ARDSGAALLA KHAGVVEYVD GNEIRVRRTS
710 720 730 740 750
GELDIYNITK YRRSNSGTSY NQRPLARLGE KVEKNDIIAD GPSMENGEMA
760 770 780 790 800
LGQNPLVAYM TWEGYNFEDA VIMSERLIKD DVYTSIAIEE YESETRDTKL
810 820 830 840 850
GPEEITREIP NVGDEALKNL DESGIIRIGA EVKDGDLLVG KVTPKGETDP
860 870 880 890 900
TPEERLLRAI FGEKAREVRD TSLRVPHGGG GIVHDVRVFT RENGDELPSG
910 920 930 940 950
VNKLVRVFIA QKRKIHVGDK MAGRHGNKGV VSNIVPVEDM PYLPDGTPID
960 970 980 990 1000
IMLNPLGVPS RMNIGQVMEL HLGMAARTLG IHIATPVFDG ASDEDIWDTV
1010 1020 1030 1040 1050
KEAGMAADAK TVLYDGRTGE PFDNRISVGV MYMIKLHHMV DDKLHARSVG
1060 1070 1080 1090 1100
PYSLVTQQPL GGKAQFGGQR FGEMEVWALE AYGAANVLQE ILTYKSDDVI
1110 1120 1130 1140 1150
GRTRAYEAIV KGERIPKPGL PESFRVLVKE LQSLGLDMKV LDADRNVLDL
1160 1170 1180 1190
RELDEDEVMT RPDNTEITPE MLEAQEAIVA QAEAEEEALI NADIEK
Length:1,196
Mass (Da):133,169
Last modified:March 6, 2007 - v1
Checksum:i53DF3C2480A3CEE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA Translation: CAL98553.1
RefSeqiWP_011835718.1, NC_009004.1

Genome annotation databases

EnsemblBacteriaiCAL98553; CAL98553; llmg_1982
KEGGillm:llmg_1982

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA Translation: CAL98553.1
RefSeqiWP_011835718.1, NC_009004.1

3D structure databases

ProteinModelPortaliA2RML9
SMRiA2RML9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi416870.llmg_1982

Proteomic databases

PRIDEiA2RML9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL98553; CAL98553; llmg_1982
KEGGillm:llmg_1982

Phylogenomic databases

eggNOGiENOG4108IIJ Bacteria
COG0085 LUCA
HOGENOMiHOG000218611
KOiK03043
OMAiFMTWEGY

Family and domain databases

CDDicd00653 RNA_pol_B_RPB2, 1 hit
Gene3Di2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit
HAMAPiMF_01321 RNApol_bact_RpoB, 1 hit
InterProiView protein in InterPro
IPR019462 DNA-dir_RNA_pol_bsu_external_1
IPR015712 DNA-dir_RNA_pol_su2
IPR007120 DNA-dir_RNAP_su2_dom
IPR037033 DNA-dir_RNAP_su2_hyb_sf
IPR010243 RNA_pol_bsu_bac
IPR007121 RNA_pol_bsu_CS
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
IPR007645 RNA_pol_Rpb2_3
IPR007641 RNA_pol_Rpb2_7
IPR014724 RNA_pol_RPB2_OB-fold
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 2 hits
PF04565 RNA_pol_Rpb2_3, 1 hit
PF10385 RNA_pol_Rpb2_45, 1 hit
PF00562 RNA_pol_Rpb2_6, 1 hit
PF04560 RNA_pol_Rpb2_7, 1 hit
TIGRFAMsiTIGR02013 rpoB, 1 hit
PROSITEiView protein in PROSITE
PS01166 RNA_POL_BETA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB_LACLM
AccessioniPrimary (citable) accession number: A2RML9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 6, 2007
Last modified: October 10, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again