Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 63 (12 Aug 2020)
Sequence version 1 (20 Feb 2007)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Alpha-L-fucosidase

Gene

TVAG_064890

Organism
Trichomonas vaginalis
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseARBA annotation, Hydrolase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-L-fucosidaseARBA annotation (EC:3.2.1.51ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TVAG_064890Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTrichomonas vaginalisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5722 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetamonadaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001542 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
TrichDB:TVAG_064890

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei972 – 997HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5722.XP_001320164.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini340 – 478F5/8 type CInterPro annotationAdd BLAST139

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 29 family.ARBA annotation

Keywords - Domaini

RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3340, Eukaryota

KEGG Orthology (KO)

More...
KOi
K01206

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 3 hits
2.60.40.2030, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038081, CalX-like_sf
IPR003644, Calx_beta
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR000933, Glyco_hydro_29
IPR017853, Glycoside_hydrolase_SF

The PANTHER Classification System

More...
PANTHERi
PTHR10030, PTHR10030, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01120, Alpha_L_fucos, 1 hit
PF03160, Calx-beta, 2 hits
PF00754, F5_F8_type_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00812, Alpha_L_fucos, 1 hit
SM00237, Calx_beta, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141072, SSF141072, 2 hits
SSF49785, SSF49785, 1 hit
SSF51445, SSF51445, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50022, FA58C_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2EHG3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIFFSILTNS VKPPAPWGPQ GTHAQIQYQR EELAAFVHYG MNTYTGVEWG
60 70 80 90 100
NGHENEDLFN PTNLNTDQWV TSIQKAGFKR LIFVGKHHDG FCIWKTNYTV
110 120 130 140 150
HNVNRSAKFQ ATSKQRGQSG DVIEELSKSC SKYNMNMGFY LSPLDMNNSA
160 170 180 190 200
YGNEELYNEF YMNQLREILG NKKYGNNGKF VEVWMDGAKS EAAKDQKYWF
210 220 230 240 250
LKWFDIIDKL QPDSVVFSPY GSTVRWIGNE RGYAGNLCWS RVNLSRMRGG
260 270 280 290 300
NTIGLGEYEY YFHGDPDGDI WSVGECDVSI TSGWFWTEGR VPKSMQELAD
310 320 330 340 350
IYFNSVGHGQ PLLLNVPPNK EGVLPDNMVK RLEEFGETIR KTYEVNFANQ
360 370 380 390 400
PDVKVTASSF RGNDPQFKPE NAVDDNISTY WTMDDNVTKG WIEIDLGQKR
410 420 430 440 450
TFDIVSFSEH IDLGQRVEEW FLYYFDSSKN DWVLFENGTT INTRHLCWQH
460 470 480 490 500
PVTSQKIKLV ITKSQDVPLI ERIGVYKGYG AFSKKSLIPE GLTEVLAAKF
510 520 530 540 550
NKTGNWNNED EGIWTRQVGA SVSYKFIGSK VYVVGIVDPG HGKIGVYIDG
560 570 580 590 600
NKITVINTKA DERKLRQLLY TSPDLDYGDH EIKLVLESTA CALHGFYYLD
610 620 630 640 650
NKGMGMFQIR NANYAIAKGG KVKIQVDRIG GSSGKCSVTF QTVPGTAVHG
660 670 680 690 700
KHYINVLEKL NFEDGEKTKL ILVKTIENPE ITSNLTFFAQ VVDPSEGSLI
710 720 730 740 750
GFNDISEITI YDGKPIEGLI DIDRKDMDFD GSWEDKGDVV VSSDVGANIE
760 770 780 790 800
AQFYGTKVFI IGNKSPNTGE ILVFIDNKKV GIIDTHSEYL QKDQLLFTSD
810 820 830 840 850
DLELPNSLSL SSHSIVLVLI SKRCEIKKFT VLENNATGMI SLENEKLTIK
860 870 880 890 900
GGNKIDFKIL RSGGNDGECS VRLQTLPGTA VEGKDYKPID QIVSFLTGQN
910 920 930 940 950
EKKVQIETME NDKDDVDFYL TISEPTNDVV VKFNSSCAIK ISNTIPSPIT
960 970 980 990 1000
ETPVPPISYT STPDPQPKNK KVMIIVISLS CGIIVVAILG FIIYRIVKSR
1010 1020
ENEKFPMISK ELSSGSNTNY I
Length:1,021
Mass (Da):114,780
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5A0F423EE4FE3951
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS113389 Genomic DNA Translation: EAY07941.1

NCBI Reference Sequences

More...
RefSeqi
XP_001320164.1, XM_001320129.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4765836

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tva:TVAG_064890

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS113389 Genomic DNA Translation: EAY07941.1
RefSeqiXP_001320164.1, XM_001320129.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5722.XP_001320164.1

Genome annotation databases

GeneIDi4765836
KEGGitva:TVAG_064890

Organism-specific databases

EuPathDBiTrichDB:TVAG_064890

Phylogenomic databases

eggNOGiKOG3340, Eukaryota
KOiK01206

Family and domain databases

Gene3Di2.60.120.260, 3 hits
2.60.40.2030, 2 hits
InterProiView protein in InterPro
IPR038081, CalX-like_sf
IPR003644, Calx_beta
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR000933, Glyco_hydro_29
IPR017853, Glycoside_hydrolase_SF
PANTHERiPTHR10030, PTHR10030, 1 hit
PfamiView protein in Pfam
PF01120, Alpha_L_fucos, 1 hit
PF03160, Calx-beta, 2 hits
PF00754, F5_F8_type_C, 1 hit
SMARTiView protein in SMART
SM00812, Alpha_L_fucos, 1 hit
SM00237, Calx_beta, 2 hits
SUPFAMiSSF141072, SSF141072, 2 hits
SSF49785, SSF49785, 1 hit
SSF51445, SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS50022, FA58C_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2EHG3_TRIVA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2EHG3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: August 12, 2020
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again