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Protein
Submitted name:

Dynein heavy chain family protein

Gene

TVAG_006480

Organism
Trichomonas vaginalis
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein heavy chain family proteinImported
Gene namesi
ORF Names:TVAG_006480Imported
OrganismiTrichomonas vaginalisImported
Taxonomic identifieri5722 [NCBI]
Taxonomic lineageiEukaryotaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas
Proteomesi
  • UP000001542 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiTrichDB:TVAG_006480

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi412133.XP_001323796.1

Structurei

3D structure databases

ProteinModelPortaliA2E755
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1904 – 2048AAAInterPro annotationAdd BLAST145
Domaini2182 – 2310AAAInterPro annotationAdd BLAST129
Domaini2513 – 2981AAAInterPro annotationAdd BLAST469

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili777 – 801Sequence analysisAdd BLAST25
Coiled coili1163 – 1190Sequence analysisAdd BLAST28
Coiled coili3125 – 3145Sequence analysisAdd BLAST21
Coiled coili3181 – 3201Sequence analysisAdd BLAST21
Coiled coili3368 – 3409Sequence analysisAdd BLAST42
Coiled coili3417 – 3451Sequence analysisAdd BLAST35
Coiled coili3674 – 3708Sequence analysisAdd BLAST35
Coiled coili4388 – 4415Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
InParanoidiA2E755
KOiK10408

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 5 hits

Sequencei

Sequence statusi: Complete.

A2E755-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADPRYKFLW TKIAENLLFE NSNAVEDWAA NLSGEQMSKI NNFLSTHDEV
60 70 80 90 100
PALFFYVTSR EPLEMTVSDD PSEYPGKSCI LTPYFLKIEK ENKQALSNNN
110 120 130 140 150
IDQLVAAGII AGDPISSFNS MFSKSYSGVI RTALDSADEG IDRKSLNIIL
160 170 180 190 200
TGIERKSQSI SSTVEATSKA VILEPPADMH GVTLDSQSLL QASHDDSITN
210 220 230 240 250
KFAQKMQQWC EQIQGLLNVT EQVRQEDEDS GPRAEMDYWR ERLSIFSSLV
260 270 280 290 300
ESIKSNDVRI VVSVLKIKRP PILTLWNELD AKITASANEA KDNVKYLTSL
310 320 330 340 350
EKYTELLYAL DPPECGELVP GLITSVSMVH NISRYYRSPQ RICTLLKKVT
360 370 380 390 400
NQMINTCVHY ICPSGQLYEQ DRTLLIKKFH ECIDLNKRYQ ECYNNTMKTK
410 420 430 440 450
VPSLDTTQPA NKTGDLNKTG KSSDKKDDSN TTRELKTHFI IFGKFDAFSE
460 470 480 490 500
RCDYLINLFT TINEFNNLSK CRLEGMAPIV TRFVEDIDFT KRVSYKMLDP
510 520 530 540 550
RNQTFQKDYK LFQTNCVQLD TQIRQIISDA FQVTPTPMAA LDLYTELSGT
560 570 580 590 600
MTRQQGKAEL EKWFTKTLTR YSEDLDLVDK EQQQMASSFN NKKLQIKNMP
610 620 630 640 650
PIAGCIARTR QLMDRITGPM EVFKKHEGVF DKGENKKLVA KYNPTLYKLA
660 670 680 690 700
DLEKKCYELF QDNAALLKKE MQNTLIKMDS NHVLTVNFSH DVLRIFQEAN
710 720 730 740 750
VFCRFKFDLP PQFESFVSQE AHIKKCRTEL QNLLVRHDTI LFQITETFPD
760 770 780 790 800
LFRDAQMKLE AVIAPGGQTL TWSSLNIDNY IETLKQKISQ IEDVLNKVND
810 820 830 840 850
IRTFSINKSL QEIAETPLCP PFKSNITDPQ HFIDEISSHA AEAVQKINAR
860 870 880 890 900
VQGIQASVCE IINIISTVSD IDPKKEDDDG KSEPKQLFQY NKEDNTMIVT
910 920 930 940 950
GSLVWSMFKT YEEITFRAVV KCFKNSMNDL CEALKAAKEH DPTLFSTELR
960 970 980 990 1000
PTVPDLTLSP DINGIQSTLN EGVRAMLRAT QDIQTFVLAR FPSAPEQQKT
1010 1020 1030 1040 1050
EKHNEEKDRD IDEEGEPAGL AVAQNQDFRA QNYFNALTRD YPTIALIISM
1060 1070 1080 1090 1100
TNRMKEFIPK INEYTAKFNE YSFLWESDGD KSFQEFEATN PSIRQIKEKM
1110 1120 1130 1140 1150
DNFMLLESKI EDIVEKTRVG PIIIDCSGVK SALIAEAKKW KQKYGDLLNK
1160 1170 1180 1190 1200
IGRSKMLELN DFIEKMKNAL SKSINQLDDL RSTMDALKAV REKSAEYDQL
1210 1220 1230 1240 1250
MAPIEESYSL LAKNGITVPQ EELDMFDNIQ YNWGKLRALE QEQQETLQKV
1260 1270 1280 1290 1300
SPQFKNQVIE GMAQFLEDFK QFQIQYNQEG PMAPGLTPAE ASEKLKIFQH
1310 1320 1330 1340 1350
QFDNIQKRWI TYSGGQDLFG LEKTKLDSID VLAKQLKNLT TLYNLYSEVN
1360 1370 1380 1390 1400
TYTRQIRDFL WVEVKFSDIE VKMTEFQTRT RHLPAEMRGW AAYQDLGQKI
1410 1420 1430 1440 1450
DNFVDTMPLL EALSNPAVKP VHWDEIKKLT HVDIDTDKDV FRLGHVFDAG
1460 1470 1480 1490 1500
LLNFKEDVQD ICNAATQEAK IEAKLREIEG DWQATEFTFS PYKGMQDMLL
1510 1520 1530 1540 1550
KGAETNEIIT KIEDSLMALS SLNSNRFVAR FKSQVESWMK KLSVSRDVIT
1560 1570 1580 1590 1600
EWQQVQSMWI YLEAVFSGGD IAKYMTQETK AFAQINKNWM TIMKNASDVK
1610 1620 1630 1640 1650
NVVTVCFVDE GLAKLFKHLL EQLQKCQKAL SGYIEKKRQS FPRFYFLSEP
1660 1670 1680 1690 1700
VILEILGQAS DPQAIQPHIH SIFDNLTHLE FDQMQYNKIL GFESGEGEKV
1710 1720 1730 1740 1750
KLYQPFLAQD NVEKWLNDLI NKMRQTLLNI CTEMSTQIQT FTVEQWVNAD
1760 1770 1780 1790 1800
FPAQIMLLAM MIWWTERTED TLKRANGKNQ KIFKETKDEF EMRFKKLVEI
1810 1820 1830 1840 1850
AGGLDKSKKL KSVHIEVLIT LFLHNRDIYN SLVDMKIKSP LDFEWQKQMR
1860 1870 1880 1890 1900
YYWKPEGRKC IIAITDVERE YSYEYLGCTG RLVITPLTDR CYITLAQALG
1910 1920 1930 1940 1950
LSMGGAPAGP AGTGKTETVK DMAKALGIMC VVFNCSDQMN NQGLGRIFRG
1960 1970 1980 1990 2000
LAQAGCWGDF DEFNRIELDV LSVAAQQVAT IFNACRERQR IFKFVDGNMV
2010 2020 2030 2040 2050
ELDNRVAIFI TMNPGYAGRQ ELPENLKIQF RMVAMMVPDK RLIMKVKLAS
2060 2070 2080 2090 2100
SGFQDYMSLS DKFALLYALC SEQLSKQIHY DWGLRNILSV LRFSKEVRAN
2110 2120 2130 2140 2150
NPTMNEQELL NRVLMNMNLA KLVDDDEPLF LDLLQDVFDK KPDQQPDMAI
2160 2170 2180 2190 2200
KNSIIENAVA HGLDPFPEWM AKAMQLQETC EVRHGIMILG PSGSGKSSLL
2210 2220 2230 2240 2250
KMLILAYSEV RCPHEFVRMN PKAITSSQMF GTLDPSSNDW TDGIFSSLWR
2260 2270 2280 2290 2300
MACKKTNKNV WLGLDGPVDA IWIENLNSVL DDNKTLTLAN GDRLPMAPTV
2310 2320 2330 2340 2350
KLLFEMSSLD NASPATVSRA GMIYVPSHIL TWRPLAMSWS KREDFKAIER
2360 2370 2380 2390 2400
IFPELISSFD KLFAYVFKHL KMVMKTSQVH VITTILHIFE AMITSRESDG
2410 2420 2430 2440 2450
FIKLNCQDPA ILKKLMIFSA MWAFGGFLDL DGRAQLSQWL CKEYAASIPS
2460 2470 2480 2490 2500
SIDKAKLFDY VVDLKSGGEW VNWEERLKTY EYPKKETPEF ASILVPTINN
2510 2520 2530 2540 2550
TQIEYLLQLL AQSGRSILLF GDSGTAKTAT INTFLNTFDK ERWVSKVFNF
2560 2570 2580 2590 2600
SSATTPYLFQ TSIESVLEKT IGSSYGPIGG KRMEVFIDDI SMPEINEWGD
2610 2620 2630 2640 2650
QVTNEIVRQL MEDSGFYSLE KPGEFITVIN TQFVAAMCTP GGGRNDVPDR
2660 2670 2680 2690 2700
LKRHFSVFNY TLPDVASINR IYATILKGFF VEERGFSQSI CNLAGTAVDA
2710 2720 2730 2740 2750
THAIWSATKG RMLPTPAKFH YVFNLRDLSR VTQGMLQVTS KEVNTPELFV
2760 2770 2780 2790 2800
SLWAHECFRV FPDKFTTDQD KAWFSEAIVK TGCEKFGDAY EHLLREASTR
2810 2820 2830 2840 2850
LWCSFMHDPD YSQYEGVEDS KIPRIYEQVS TFDALNKRCR EFMDEFNSKP
2860 2870 2880 2890 2900
STKGKKLDLV LFDDAMNHLV RIARIIGMPR GHALLVGVGG SGKQSLTRLA
2910 2920 2930 2940 2950
STILGYNIFQ VTPGRNYGTN DFLTDIRELY RQAGVLNKRT TFIFTDNEVK
2960 2970 2980 2990 3000
QESFLEFINN ILTTGEIANL FYRDTYEALM SEMRPIFIKE CRGQVDTDQN
3010 3020 3030 3040 3050
VYGYFINRVR SNLHIVLCFS PVGEQFRKRN LKFPGLFSGC TIDWFTHWPH
3060 3070 3080 3090 3100
QGLYSVVENF LKPIDIIAKD SDIKERLSET FALIHESVEQ GCEDYFNRFR
3110 3120 3130 3140 3150
RRTFVTPKSY LSFLSSFKTL YQTQLEKIQD DANRMKEGLQ KIEDAKVSVA
3160 3170 3180 3190 3200
NMKSKLSEEK AVVAQKSAEA QQILDVVTVK RAEAETQAAE VQTQKDAQEV
3210 3220 3230 3240 3250
EKNKIAVMQE DANAKLQDAM PAKIEAEKAL QSLTSGDMNE LKGYAQIGAV
3260 3270 3280 3290 3300
IMLVFDAVCI LLYDKILPYT PEELSTKDGT FQFMTPSLEY GNNYRKSTTL
3310 3320 3330 3340 3350
LQTLVNYPKD QINDEQIDLL QPYLTCPIFN PTVAKKASTA AGGICSWVIN
3360 3370 3380 3390 3400
VCKYHAVEKG VRPLKLQLDQ ATASLNKAEA ALKVLEDALA EKQRALDELQ
3410 3420 3430 3440 3450
RNYDAALGKQ NECTMRAQAT EKKLKDAQTL IDALSNEKSR WETQASMLQE
3460 3470 3480 3490 3500
SILKTVGNAT IGAAFNSYCG MFNHVMRQHF LNEAWPNILA SNQIPSQGQI
3510 3520 3530 3540 3550
DIISLFVTEA TLDTWQLQGL PSDELSRQNG VISTNAPTYP LLIDPQGQAH
3560 3570 3580 3590 3600
SWIMNRHKQD LIVTSFEDKY FRTHLENALQ SGRPLLIEDC GEEIDPILDN
3610 3620 3630 3640 3650
ILAKNYMKVG RSINVSVGGK DVEVYQGFTL YFTTKLANPK FSPETFAKCS
3660 3670 3680 3690 3700
VIEFSVTQNG LQEQLLNLVI LREKESLEID RQRLLAKVAA LKASLVDLEN
3710 3720 3730 3740 3750
KLLDLLRSSK GDLLENTSLI TTLNSTKVTS KENTESLNEA MTTNQKIENS
3760 3770 3780 3790 3800
RKEYMPVALR GAVIYFLIQD LANVNYMYQI SLNQFLGKFF QAIEEAPPDP
3810 3820 3830 3840 3850
MTQTRIANII QTLTYLCFTY IVRGLYEKDK LLFTLQLALK IQLSLNVFDF
3860 3870 3880 3890 3900
NDYQIFLKGG AAFSGGDKMG DVQLPDIFSQ VKENVLALSQ ISLFKGHFTE
3910 3920 3930 3940 3950
ITDQVPKWKE LMESQAPENM EPPHICENMT PFHNAVIIRC IRPDRAIFAA
3960 3970 3980 3990 4000
NKYIGEVLGK EFLEYTMPSL DVISAEAGNQ SPVIYLLSAG SDPTPLVEEA
4010 4020 4030 4040 4050
AKKAKIPISS ISMGQGREEI AEAAIQNAKH KGEWVLLQNC HLGLKYMAAL
4060 4070 4080 4090 4100
FEMYKTDIAN TANAQEKKEE AKDAGAAAAP AKEGEQKKPE KEKVKSVHPD
4110 4120 4130 4140 4150
YRLWITTEPN PRFPVNLLQL SIKLTNEPPA GAKANLKRTI LSLNQQTIEQ
4160 4170 4180 4190 4200
LEVSEWRRLI YVLAFFNTTV QERRKFGPLG WCIPYEFNHS DFTASLAFCS
4210 4220 4230 4240 4250
AQIVDAQRVS PNPNTNPNVF QQSFWQTVRY GICEIHYGGR VTDELDRRLI
4260 4270 4280 4290 4300
NAIGENYFNN ERVFDNVPGA QKYFDVSGAD PKEVGKYPIL DCINVNQFLD
4310 4320 4330 4340 4350
AIKNLPQNDP PEVFGLNAIA DVKLRRDQAD EIFQKIIDIQ PKESSVGGMT
4360 4370 4380 4390 4400
REDVVMKRCQ ELLPQVPENF NMEQVRKTVV DNGSKPLYVC AKQEIERMQN
4410 4420 4430 4440 4450
VLKVLRSTLT DLMAAIDGTI VMNDQLYGSM NSLFDGRIPR HWLRISWPAD
4460 4470 4480 4490 4500
TLKGWFDEVK ARYQQYNTWI QQGTKMDTFW LGGMFNPGGF VTSLRQETVR
4510 4520 4530 4540 4550
ANAGWQLDQT SLDSEVQPLG GRSTKGDNDK PVNGPTIVSV YCRGFWLEGA
4560 4570 4580 4590 4600
RWIKTVGANS NTTYGLAELV SVTGKGKSQK LVTDLRNEMP LIKLGTSQRD
4610 4620 4630 4640 4650
PKAKPPPVIP LSKDRTYMAP IYKSSQRTDL NYIISIPLQT ADPKLFAIHW
4660
VLRGVCLTTK
Length:4,660
Mass (Da):530,193
Last modified:February 20, 2007 - v1
Checksum:i9E93FC10E575CA10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS113317 Genomic DNA Translation: EAY11573.1
RefSeqiXP_001323796.1, XM_001323761.1

Genome annotation databases

EnsemblProtistsiEAY11573; EAY11573; TVAG_006480
GeneIDi4769527
KEGGitva:TVAG_006480

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS113317 Genomic DNA Translation: EAY11573.1
RefSeqiXP_001323796.1, XM_001323761.1

3D structure databases

ProteinModelPortaliA2E755
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi412133.XP_001323796.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAY11573; EAY11573; TVAG_006480
GeneIDi4769527
KEGGitva:TVAG_006480

Organism-specific databases

EuPathDBiTrichDB:TVAG_006480

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
InParanoidiA2E755
KOiK10408

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA2E755_TRIVA
AccessioniPrimary (citable) accession number: A2E755
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: December 20, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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