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Entry version 60 (08 May 2019)
Sequence version 1 (20 Feb 2007)
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Protein
Submitted name:

Ankyrin repeat protein, putative

Gene

TVAG_465440

Organism
Trichomonas vaginalis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin repeat protein, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:TVAG_465440Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTrichomonas vaginalisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5722 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001542 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
TrichDB:TVAG_465440

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini204 – 1142ANK_REP_REGIONInterPro annotationAdd BLAST939
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati204 – 236ANKPROSITE-ProRule annotationAdd BLAST33
Repeati237 – 269ANKPROSITE-ProRule annotationAdd BLAST33
Repeati271 – 303ANKPROSITE-ProRule annotationAdd BLAST33
Repeati304 – 336ANKPROSITE-ProRule annotationAdd BLAST33
Repeati337 – 369ANKPROSITE-ProRule annotationAdd BLAST33
Repeati370 – 402ANKPROSITE-ProRule annotationAdd BLAST33
Repeati403 – 435ANKPROSITE-ProRule annotationAdd BLAST33
Repeati436 – 468ANKPROSITE-ProRule annotationAdd BLAST33
Repeati469 – 501ANKPROSITE-ProRule annotationAdd BLAST33
Repeati502 – 534ANKPROSITE-ProRule annotationAdd BLAST33
Repeati535 – 567ANKPROSITE-ProRule annotationAdd BLAST33
Repeati568 – 600ANKPROSITE-ProRule annotationAdd BLAST33
Repeati601 – 633ANKPROSITE-ProRule annotationAdd BLAST33
Repeati634 – 666ANKPROSITE-ProRule annotationAdd BLAST33
Repeati668 – 700ANKPROSITE-ProRule annotationAdd BLAST33
Repeati701 – 733ANKPROSITE-ProRule annotationAdd BLAST33
Repeati734 – 766ANKPROSITE-ProRule annotationAdd BLAST33
Repeati767 – 799ANKPROSITE-ProRule annotationAdd BLAST33
Repeati801 – 833ANKPROSITE-ProRule annotationAdd BLAST33
Repeati834 – 866ANKPROSITE-ProRule annotationAdd BLAST33
Repeati867 – 899ANKPROSITE-ProRule annotationAdd BLAST33
Repeati901 – 933ANKPROSITE-ProRule annotationAdd BLAST33
Repeati934 – 966ANKPROSITE-ProRule annotationAdd BLAST33
Repeati968 – 1000ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1001 – 1033ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1034 – 1066ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1067 – 1099ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1101 – 1133ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili114 – 134Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0504 Eukaryota
KOG4177 Eukaryota
COG0666 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2DU09

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 8 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 11 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 11 hits
PF13606 Ank_3, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 28 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 28 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2DU09-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLNFEYIAA HISDYINNEN FFDTFDMRDI KIIMKNSHLT ADQYVTLLKQ
60 70 80 90 100
SSSTLNSKEL YIYTRKANVR VQNLEEVVSI LNSVKRYMKF NIFDGITDFL
110 120 130 140 150
KQNEKVINDS TNEREIIQDK SKAFQKENEN ATKDTTVNVT NENYNHSRDI
160 170 180 190 200
LTKITELKES SDFETVYKFL DELSSTGNHE MISKSIEEGL WKKIAPKIYE
210 220 230 240 250
YDDHERNVLH FASEKGNLRL VQSLIECGCD KESKDNDGYT PLICASSNGH
260 270 280 290 300
LEVVQYLISV GADKEAKDNS LGYTPLIFAS SNGHLEVVKY LISVGADKEA
310 320 330 340 350
KDNDGYTPLI CASSNGHLEV VQYLISVGAD KEAKDNDGYT PLICASSNGH
360 370 380 390 400
LEVVKYLISV GADKEAKDNN GYTPLIFASS NGHLEVVKYL ISVGADKEAK
410 420 430 440 450
DKDGYTPLIF ASSNGHLEVV QYLISVGADK EAKDNDGYTP LICASSNGHL
460 470 480 490 500
EVVKYLISVG ADKEAKNNNG YTPLICASSN GHLEVVKYLI SVGADKEAKD
510 520 530 540 550
NDEYTPLIFA SSNGHLEVVQ YLISVGADKE AKDKDGWTPL ICASSNGQFE
560 570 580 590 600
VVKYLISVGA DKEAKDNDGY TPLIFASSNG HLEVVQYLIS VGADKEAKDK
610 620 630 640 650
DGWTPLICAS SNGQFEVVKY LISVGADKEA KDNDGYTPLI CASSNGHLEV
660 670 680 690 700
VQYLISVGAD KEAKDNSLGY TPLIWASSNG HLEVVKYLIS VGADKEAKDN
710 720 730 740 750
DGYTPLICAS SNDQFEVVKY LISVGADKEA KDNDGYTPLI WASSNGHLEV
760 770 780 790 800
VKYLISVGAD KEAKDNDGYT PLIFASSNGH LEVVQYFISV GADKEAKDNS
810 820 830 840 850
LGYTPLIFAS YNDQFEIVKY LISVGADEEA KNNNGYTPLI FASSNGHLEV
860 870 880 890 900
VQYLISVGAD KEAKDKDGWT PLICASSNDQ FEVVKYLISV GADKEAKDNS
910 920 930 940 950
LGYTPLIWAS SNGHLEVVKY LISVGADKEA KDNDGYTPLI FASSNGHLEV
960 970 980 990 1000
VQYFISVGAD KEAKDNSLGY TPLIFASYND QFEIVKYLIS VGADKEAKNN
1010 1020 1030 1040 1050
NGYTPLIFAS SNGHLEVVQY LISVGADKEA KDKDGWTPLI CASSNDQFEV
1060 1070 1080 1090 1100
VKYLISVGAD KEAKDKDGWT PLIFASSNGH LEVVQYLISV GADKEAKDNS
1110 1120 1130 1140 1150
LGYTPLIFAS SNGHLEVVKY LISVGADKEA KDNFGNTALD VARGSVKEYF

LEDKTE
Length:1,156
Mass (Da):126,709
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4264CE60E4031C40
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS113246 Genomic DNA Translation: EAY16156.1

NCBI Reference Sequences

More...
RefSeqi
XP_001328379.1, XM_001328344.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAY16156; EAY16156; TVAG_465440

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4774163

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tva:TVAG_465440

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS113246 Genomic DNA Translation: EAY16156.1
RefSeqiXP_001328379.1, XM_001328344.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAY16156; EAY16156; TVAG_465440
GeneIDi4774163
KEGGitva:TVAG_465440

Organism-specific databases

EuPathDBiTrichDB:TVAG_465440

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
KOG4177 Eukaryota
COG0666 LUCA
InParanoidiA2DU09

Family and domain databases

CDDicd00204 ANK, 8 hits
Gene3Di1.25.40.20, 11 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 11 hits
PF13606 Ank_3, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 28 hits
SUPFAMiSSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 28 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2DU09_TRIVA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2DU09
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 8, 2019
This is version 60 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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