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Entry version 80 (16 Jan 2019)
Sequence version 1 (20 Feb 2007)
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Protein
Submitted name:

Golgin A3

Gene

golga3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Golgin A3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:golga3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-060526-252 golga3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
A2CEB4

PeptideAtlas

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PeptideAtlasi
A2CEB4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSDARG00000062511 Expressed in 18 organ(s), highest expression level in female gonad

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000115821

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili138 – 172Sequence analysisAdd BLAST35
Coiled coili416 – 464Sequence analysisAdd BLAST49
Coiled coili500 – 583Sequence analysisAdd BLAST84
Coiled coili676 – 713Sequence analysisAdd BLAST38
Coiled coili721 – 783Sequence analysisAdd BLAST63
Coiled coili791 – 982Sequence analysisAdd BLAST192
Coiled coili1012 – 1130Sequence analysisAdd BLAST119
Coiled coili1145 – 1211Sequence analysisAdd BLAST67
Coiled coili1226 – 1288Sequence analysisAdd BLAST63
Coiled coili1293 – 1323Sequence analysisAdd BLAST31
Coiled coili1328 – 1355Sequence analysisAdd BLAST28
Coiled coili1363 – 1397Sequence analysisAdd BLAST35
Coiled coili1433 – 1460Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFW4 Eukaryota
ENOG410YGSW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154088

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112752

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051753

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2CEB4

Database of Orthologous Groups

More...
OrthoDBi
87408at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2CEB4

TreeFam database of animal gene trees

More...
TreeFami
TF332014

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033288 Golga3

The PANTHER Classification System

More...
PANTHERi
PTHR18902:SF26 PTHR18902:SF26, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2CEB4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENGNNGMVS IEAKPPQHPD AQHCKNPNSN TVESLKPERS LVTEKIPNGH
60 70 80 90 100
VKAELLPNGE AMVEGQDVGG GSTPPSATPS PGSRLSDSSP STELDPGVVS
110 120 130 140 150
FPDSLERSEG SVHTGDALQS LRLSIPMQET ELSSTDPCVE MENEEKIRQE
160 170 180 190 200
ARRRLEEQLK QYRAQRHTER TRRSTPKSRP FSTLDPELML HPEGLPRANT
210 220 230 240 250
VAMTKEYSFL RTSVPRGPKL GSLGIPSSRE KKSKSSRSSK IHSLADYKTP
260 270 280 290 300
ESEGSGGAVS ASADSSFTSL HSTISSVSTV SEISISSEAN NHSESSQLIR
310 320 330 340 350
DNISEVDGSE SGFRADGNDS DSSSYSSVST TGTYNMLSAI VNRPKAPYTV
360 370 380 390 400
EGREIAAEAM GHFPSLQEVL QAATEERHME ELEQDREGSV EPRSRRDSFS
410 420 430 440 450
SSVSYGSSVM GTHDEMLQVL KEKMRLEGQL ESLSSEASQA LKEKTELQAQ
460 470 480 490 500
LATVNAQLKA QVEQTQAGQE RQSTLKTEVT TLRSNCSALE KAMVDLQTNL
510 520 530 540 550
EGKNASLASL GNDLEVAEEQ YQRLMVKVEE MQQSLNAKDN TVSELRQQMG
560 570 580 590 600
GLQTQLQRVQ SERNALQSRL KTSQAEVDSL QQLRLWYQQQ LNLAQEARVR
610 620 630 640 650
LQGEMANMQA GQMTQFGVLE NLKIENVTLS HKLTETNHRS IKEKERIAVQ
660 670 680 690 700
LQSIEADMLT QEAAIHQIQE AKTMVEEDLQ HKLEEFEEER EHLLKLANTA
710 720 730 740 750
TTLERELEQV KLVLFQKDSQ LESLQREHLE LMKQLTTTQE TLQTKEQALN
760 770 780 790 800
QLEARYQELQ VQLEELQTDA SAKEETLQYL QNEKIVLEVA LQAARADKSE
810 820 830 840 850
LDEGAEKLGE EVLVASDTLD QLRQEVQVKA TQIEALQHEN GTLKKQAQKL
860 870 880 890 900
KEQFMQQKVM VEAYRRDASS KEQLISELKA SKKRLVAEVK DLKQELLKTE
910 920 930 940 950
GEKKSAVQEQ ARLQKEVERV QQQMNGLEAH LQSVQTERDQ LDSQLQSLQF
960 970 980 990 1000
DQNQLAAVTE ENENLRKRVE QMQNEARTAI SEQKVKMKRL GTDLTSAQKE
1010 1020 1030 1040 1050
MKAKHKAYEN AVGILSRRLQ EALAAKETAE AELDKLKAQV ADGGNSQELQ
1060 1070 1080 1090 1100
AKVKSLQGEL QAVSQSKAML EKELQEVITL TSTELEEYQE KVLELEDEQL
1110 1120 1130 1140 1150
QESRNFKKRI RRLEDANKKL ALELEHEKGK LSGLGKSHSA LREHANILEA
1160 1170 1180 1190 1200
ALAKREADLV QLNLQVQAVL KRKEEEDQQM RQLVQTLQTA LEKEKIKVKD
1210 1220 1230 1240 1250
LTEQVAEAKL EAAHNRRHYR AAVLELSEIK KDLQAKEELV KALEKEATTL
1260 1270 1280 1290 1300
AAQDEKHSEE VSRFREELAD AHTQLQILQK QLDDELNKQP VTNQEVEDLK
1310 1320 1330 1340 1350
WEVEQKQREM EAQKQQLEMV EQCHQREMQS QQDMLQTIKV ELEMVQEELN
1360 1370 1380 1390 1400
GTRKDKFMLQ AKVGELRNSM KTVLQQNNQL KQDLKNSRLR KQRMDLKGES
1410 1420 1430 1440 1450
TPVTPVKIPD CPVPASLLDE LLKPSTSVNK EPLNNLHNCL KQLKQEMDSL
1460 1470 1480 1490
QKQMEEHTVT VTSLASPEDE LQKLGLHDSS ESSNKEDKEE MLPS
Length:1,494
Mass (Da):168,503
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC449520739D448B7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CR388061 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
NP_001122017.1, NM_001128545.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Dr.42542

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000137022; ENSDARP00000115821; ENSDARG00000062511

Database of genes from NCBI RefSeq genomes

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GeneIDi
570879

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:570879

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388061 Genomic DNA No translation available.
RefSeqiNP_001122017.1, NM_001128545.1
UniGeneiDr.42542

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000115821

Proteomic databases

PaxDbiA2CEB4
PeptideAtlasiA2CEB4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000137022; ENSDARP00000115821; ENSDARG00000062511
GeneIDi570879
KEGGidre:570879

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2802
ZFINiZDB-GENE-060526-252 golga3

Phylogenomic databases

eggNOGiENOG410IFW4 Eukaryota
ENOG410YGSW LUCA
GeneTreeiENSGT00940000154088
HOGENOMiHOG000112752
HOVERGENiHBG051753
InParanoidiA2CEB4
OrthoDBi87408at2759
PhylomeDBiA2CEB4
TreeFamiTF332014

Gene expression databases

BgeeiENSDARG00000062511 Expressed in 18 organ(s), highest expression level in female gonad

Family and domain databases

InterProiView protein in InterPro
IPR033288 Golga3
PANTHERiPTHR18902:SF26 PTHR18902:SF26, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2CEB4_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2CEB4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: January 16, 2019
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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