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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain MIT 9303)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciPMAR59922:G1G80-1832-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:P9303_20971
OrganismiProchlorococcus marinus (strain MIT 9303)
Taxonomic identifieri59922 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002274 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238121 – 496Probable malate:quinone oxidoreductaseAdd BLAST496

Structurei

3D structure databases

ProteinModelPortaliA2CBH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A2CBH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVSDVAGSQ SRYDAVLVGA GIMSATLAAL LHELDPELRL LMVERLQAPG
60 70 80 90 100
LESSAAENNA GTGHAANCEL NYTPLQPDGS VATAKALAIN TAFERSLEFW
110 120 130 140 150
ASLTEKGKLL PQQFLHLVPH ISVVFGDADL AFLHQRFQQL SALPAFASMQ
160 170 180 190 200
WSTDAAELAE WMPLVMEGRA NAESVAATCI KRGTDVDFGL LTRAYVKSLQ
210 220 230 240 250
ASGALELSCG CEVVHLHRLG KHRWNLDLKH SSGSRSVQTP FVFLGAGGGA
260 270 280 290 300
LPLLQRSGIP EAAAYAGFPV SGQWLVCSEP GLTARHHAKV YGKAKVGAPP
310 320 330 340 350
MSVPHLDSRW IDGCRSLLFG PYAGFSSKFL KQGSRLDLLR SVRRSNFRSM
360 370 380 390 400
LEVGFKNFDL VTYLLSELQQ SEKDRFETLK QFLPNAQLND WKLSVAGQRV
410 420 430 440 450
QIIKGTAEGG RLQMGTEVVS AEDGSLAALL GASPGASTAV TVMLEVLQRC
460 470 480 490
WSERMASESW QERLQKLLPS YGHDPNSDPL LLMQMRIRSN ELLSFT
Length:496
Mass (Da):53,905
Last modified:February 20, 2007 - v1
Checksum:i0B6611DFFE7C54CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000554 Genomic DNA Translation: ABM78832.1

Genome annotation databases

EnsemblBacteriaiABM78832; ABM78832; P9303_20971
KEGGipmf:P9303_20971

Similar proteinsi

Entry informationi

Entry nameiMQO_PROM3
AccessioniPrimary (citable) accession number: A2CBH2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: February 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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