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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciPMAR167555:G1G7Z-455-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:NATL1_04721
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002592 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255091 – 496Probable malate:quinone oxidoreductaseAdd BLAST496

Interactioni

Protein-protein interaction databases

STRINGi167555.NATL1_04721

Structurei

3D structure databases

ProteinModelPortaliA2C0M6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OrthoDBiPOG091H0B7C

Family and domain databases

HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A2C0M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNTPTPDSE NTYDAILVGA GIMSSTLAVL LHELEPDLRL LVVEKLSSAG
60 70 80 90 100
LESSCAKNNA GTGHAANCEL NYTPIQEDGH LSTNKAFEIN KSFEQSLEFW
110 120 130 140 150
ASLAEKGKLI PKTFLNKLPH ISLVFGDEDI SLLKKRFSKL SSHAAFAEME
160 170 180 190 200
FTMDHGELKD WVPLIMDGRQ HSEKIAATRI KRGTDIDFGN LTRSYINQIE
210 220 230 240 250
GAKSIDINYS TNVENLQQDS EGDWYLSLEG AKNNRIVRSK FVFLGAGGGA
260 270 280 290 300
LSLLQKSRIP EGLLYAGFPV SGKWLICDEE KSTKTHNAKV YGKAAVGAPP
310 320 330 340 350
MSVPHLDTRW IDKKKSLLFG PFAGFSSNFL KYGSKLDLFR SIKTTNLFSM
360 370 380 390 400
LQAGLDNIDL GKYLLNQLIQ TNEDRIDTLK RFLPQVSPND WKLSTAGQRV
410 420 430 440 450
QIIKQTSKGG VLKMGTEVVT SSDGSLAALL GASPGASTAV TIMIEVLNRC
460 470 480 490
WLEKMKSSKW KNKMLELFPS IGTDINSDQE ALLAIRKRND FLLKLI
Length:496
Mass (Da):54,802
Last modified:March 18, 2008 - v2
Checksum:i973A19E04C9B9EE0
GO

Sequence cautioni

The sequence ABM75036 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000553 Genomic DNA Translation: ABM75036.1 Different initiation.
RefSeqiWP_041700671.1, NC_008819.1

Genome annotation databases

EnsemblBacteriaiABM75036; ABM75036; NATL1_04721
KEGGipme:NATL1_04721

Similar proteinsi

Entry informationi

Entry nameiMQO_PROM1
AccessioniPrimary (citable) accession number: A2C0M6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: February 28, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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