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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain MIT 9515)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciPMAR167542:G1G7Y-480-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:P9515_04801
OrganismiProchlorococcus marinus (strain MIT 9515)
Taxonomic identifieri167542 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000001589 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238131 – 497Probable malate:quinone oxidoreductaseAdd BLAST497

Interactioni

Protein-protein interaction databases

STRINGi167542.P9515_04801

Structurei

3D structure databases

SMRiA2BV78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A2BV78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSKKFSDKK NNYDAILVGA GIMSGTLALL LTEILPELKI LIIEKLKIPG
60 70 80 90 100
SESSGAFNNA GTGHAANCEL NYTPLDDYGH LKIEKALSIN RSFEKSMSLW
110 120 130 140 150
ASLYSSQKID IKKFLKFIPH ISFVTGSENV SFLKKRFKKM TEYKEFEDME
160 170 180 190 200
FSSSFNQISS WAPLITKSRN PLDEVAATRV KRGTDINFEV LTREYLKYIS
210 220 230 240 250
KNKNVEISYE TELNDLKKTS NKEWELNISM EGRKVNLKTS YVFLGAGGKT
260 270 280 290 300
INYLQKSNIP EAKVYGGFPV SGKWLICEEN SLTEKHNAKV YGRADIGSPP
310 320 330 340 350
MSVPHLDTRW IEGKKFLLYG PFAGFTTKFL KQGSYLDLFN SLKKNNLLSM
360 370 380 390 400
LDVGIKNNDL INYLFSQSIK SHKSRVENLR NMMPSADPSN WYLENAGQRV
410 420 430 440 450
QIIKKTKKGG SLKFGTEIVN AADGSLSALL GASPGASTAV SIMIEVLKKS
460 470 480 490
CLFTLDKSIL EQKISHLLYE SELKNQNEND FLENLKKRNN SILGFHP
Length:497
Mass (Da):55,883
Last modified:February 20, 2007 - v1
Checksum:iE561FE082A24B688
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000552 Genomic DNA Translation: ABM71689.1
RefSeqiWP_011819797.1, NC_008817.1

Genome annotation databases

EnsemblBacteriaiABM71689; ABM71689; P9515_04801
KEGGipmc:P9515_04801

Similar proteinsi

Entry informationi

Entry nameiMQO_PROM5
AccessioniPrimary (citable) accession number: A2BV78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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