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Protein
Submitted name:

Ankyrin 2b, neuronal

Gene

ank2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-445095 Interaction between L1 and Ankyrins
R-DRE-6807878 COPI-mediated anterograde transport

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin 2b, neuronalImported
Gene namesi
Name:ank2bImported
Synonyms:ank2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-041010-165 ank2b

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiA2BIB9
PeptideAtlasiA2BIB9
PRIDEiA2BIB9

Expressioni

Gene expression databases

BgeeiENSDARG00000043313
ExpressionAtlasiA2BIB9 baseline

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000114785

Structurei

3D structure databases

ProteinModelPortaliA2BIB9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 786ANK_REP_REGIONInterPro annotationAdd BLAST756
Repeati64 – 96ANKPROSITE-ProRule annotationAdd BLAST33
Repeati97 – 129ANKPROSITE-ProRule annotationAdd BLAST33
Repeati130 – 162ANKPROSITE-ProRule annotationAdd BLAST33
Repeati163 – 186ANKPROSITE-ProRule annotationAdd BLAST24
Repeati225 – 257ANKPROSITE-ProRule annotationAdd BLAST33
Repeati258 – 290ANKPROSITE-ProRule annotationAdd BLAST33
Repeati291 – 323ANKPROSITE-ProRule annotationAdd BLAST33
Repeati324 – 356ANKPROSITE-ProRule annotationAdd BLAST33
Repeati357 – 389ANKPROSITE-ProRule annotationAdd BLAST33
Repeati390 – 422ANKPROSITE-ProRule annotationAdd BLAST33
Repeati423 – 455ANKPROSITE-ProRule annotationAdd BLAST33
Repeati456 – 488ANKPROSITE-ProRule annotationAdd BLAST33
Repeati489 – 521ANKPROSITE-ProRule annotationAdd BLAST33
Repeati522 – 554ANKPROSITE-ProRule annotationAdd BLAST33
Repeati555 – 587ANKPROSITE-ProRule annotationAdd BLAST33
Repeati589 – 621ANKPROSITE-ProRule annotationAdd BLAST33
Repeati622 – 654ANKPROSITE-ProRule annotationAdd BLAST33
Repeati655 – 687ANKPROSITE-ProRule annotationAdd BLAST33
Repeati688 – 720ANKPROSITE-ProRule annotationAdd BLAST33
Repeati721 – 753ANKPROSITE-ProRule annotationAdd BLAST33
Repeati754 – 786ANKPROSITE-ProRule annotationAdd BLAST33
Domaini944 – 1132ZU5InterPro annotationAdd BLAST189
Domaini1134 – 1281ZU5InterPro annotationAdd BLAST148
Domaini3094 – 3178DeathInterPro annotationAdd BLAST85

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1731 – 1751Sequence analysisAdd BLAST21
Coiled coili3002 – 3022Sequence analysisAdd BLAST21

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00840000129677
HOVERGENiHBG095339
InParanoidiA2BIB9
OrthoDBiEOG091G00GN
PhylomeDBiA2BIB9

Family and domain databases

CDDicd00204 ANK, 6 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001969 Aspartic_peptidase_AS
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 9 hits
PF00531 Death, 1 hit
PF00791 ZU5, 3 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 23 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS00141 ASP_PROTEASE, 1 hit
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

Sequencei

Sequence statusi: Complete.

A2BIB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEDTQSHLR MEASDKLNGL GGRRRRPKKS DSNTSFLRAA RAGNIDKVLE
60 70 80 90 100
YLKGGVDIGT SNQNGLNALH LAAKEGHVDL VQELLGRGSS VDSATKKGNT
110 120 130 140 150
ALHIASLAGQ GDVVKILSKR GANINAQSQN GFTPLYMASQ ENHLDVVRYL
160 170 180 190 200
LENGGNQSIA TEDGFTPLAI ALQQGHNQVV SILLENDTKG KVRLPALHIA
210 220 230 240 250
ARKDDTKSAA LLLQNDHNAD VQSKSGFTPL HIAAHYGNVN VATLLLNRGA
260 270 280 290 300
AVDFTARNGI TPLHVASKRG NTNMVHLLLD RGAQIDAKTR DGLTPLHCAA
310 320 330 340 350
RSGHDTAVEL LLERGAPMLA RTKNGLSPLH MAAQGDHVEC VKHLLQHKAP
360 370 380 390 400
VDDVTLDYLT ALHVAAHCGH YRVTKLLLDK RANPNARALN GFTPLHIACK
410 420 430 440 450
KNRVKVMELL IKYGAFIQAI TESGLTPIHV AAFMGHLNIV LLLLQNGASP
460 470 480 490 500
DVSNIRGETA LHMAARAGQM EVVRCLLRNG AMVDARARED QTPLHIASRL
510 520 530 540 550
GKTEIVQLLL QHMAHPDAAT ANGYTPLHIA AREGHLDVTT VLLEAGAAHS
560 570 580 590 600
LATKKGFTPL HVASKYGSLE VAKLLLQRRA PPDSAGKQNG LTPLHVAAHY
610 620 630 640 650
DNQKVALLLL DKGASPHATA KNGYTPLHIA AKKNQMEIAT TLLQYGAETN
660 670 680 690 700
IQTKQGVMPI HLASQEGHSE MAALLLQRGA QVNVTTKSGL TSLHLAAQED
710 720 730 740 750
KVGVGEILVK QGANLDQQTK LGYTPLIVAC HYGNAKMVNF LLKSGASVND
760 770 780 790 800
KTKNGYTPLH QAAQQGNTHI INVLLQYGAK PNAITNGNTA LAIARRLGYI
810 820 830 840 850
SVVDTLRVVT EEIVTTTTTV TEKHKLNVPE TMTEVLDVSD EEGDDTMTGD
860 870 880 890 900
GGEYLRAEDL RELGDDSLPG QYLDGMNYLR FSLEGGRSDS LDRSYTPTHQ
910 920 930 940 950
SYYSKHYGIM EDVSSLGREN EKDSWETENL DNIALSSSPA HSGFLVSFMV
960 970 980 990 1000
DARGGAMRGC RHNGLRLIIP PRKCSAPTRV TCRLVKRHRL ATMPPMVEGD
1010 1020 1030 1040 1050
GLASRLIEVG PSGAQFLGKL HLPTAPPPLN EGESLVSRIL QLGPPGTKFL
1060 1070 1080 1090 1100
GPVIVEIPHF AALRGKEREL VILRSETGES WKEHHCEYTE EELNQVLNGM
1110 1120 1130 1140 1150
DERLDPPEEL EKKRICRIIT RDFPQYFAVV SRIKQDSNLI GPEGGVLSST
1160 1170 1180 1190 1200
VVPEVQAVFP EGALTKRIRV GLQTQPMSVD VVRNMLGNKA TFSPIVTLEP
1210 1220 1230 1240 1250
RRRKFHKPIT MTIPVPKSSA DPALGSFGGG ETPTLRLLCS ITGGTTPAQW
1260 1270 1280 1290 1300
EDITGTTPLT FTNDCVSFTT NVSARFWLID CRQVQESVNF ATLMYREIIC
1310 1320 1330 1340 1350
VPYMAKFVIF AKTHDPIEAR LRCFCMTDDK MDKTLEQQEN FSEVARSRDV
1360 1370 1380 1390 1400
EVLEGKPIYV DCFGNLVPLT KSGQHHVFSF YAFKENRLAL FIKIRDNTQE
1410 1420 1430 1440 1450
PCGRLSFTKE PRSFRTLSHG AVCNLNISLP AYSKESDSDQ EPDEETSRTL
1460 1470 1480 1490 1500
GKYDDDTETT ETSILKTHLI RDSPALASPD LLSDVSEMKQ DLIKMTAILT
1510 1520 1530 1540 1550
TDSSEKAGPM QGDYLGKGVE EVSAEPFEIM EKVKEDLEKV SEILRSGTCE
1560 1570 1580 1590 1600
KEESAKTEHR RYRKDEEWVL LTESEIEEAK MMAAFESQEA LLKEVRVNRG
1610 1620 1630 1640 1650
SQRPKGARER SGIPIGEVKE YLLDAPASQE TSSQQRFTEV VLRRGGRKIV
1660 1670 1680 1690 1700
PTMAKDTKAH TTEIKKPVRR KGPQGHTDET QSISTKENIA SKSAGKASEE
1710 1720 1730 1740 1750
DAFLPVPGDQ KKSPVSPVVE ETPIGPIKEK VKALQKKVEE EQKGHKKQTS
1760 1770 1780 1790 1800
QKPPFKSTEA KTSVLKDQKT TGLKKTSLPQ KQSSSKSPKT EPERLEETMS
1810 1820 1830 1840 1850
VRELMRAFQT GQDPSKRKSG LFEHKGPSKT EHTTMIKSEA KTTNSQCLPH
1860 1870 1880 1890 1900
SSSREVSLDV SRPVEHHEEK EVFDKDAKEN QKSHVCKQER SGEGLVFGVE
1910 1920 1930 1940 1950
SAGQQSSMTT AIAQNVSKHA SDLLPDNGTE NGTFNDSSDS IKLEALVDSP
1960 1970 1980 1990 2000
SASLAEVEAP LSSEESCKHE GMAETPETSP ESLSLSPQQK ASQSILAKAS
2010 2020 2030 2040 2050
NSTADTHKAK TSKVSVSFSA EMKTKIEQAS EATVHHPALS KAVDEPTKSE
2060 2070 2080 2090 2100
SMCIPHRKKG VNFGGEQTFV DKDIVSISTK SSKSRKLTKR PSETLESFLS
2110 2120 2130 2140 2150
DDESCDGQPT PTFADSLTLR AATQDHGGLV LPLRHQDSET LSPVADDSFN
2160 2170 2180 2190 2200
ISHKDSLEGS PLMEDNSSHK TPDSIEPSPT KESPCCDSLE NSPIEMKSNL
2210 2220 2230 2240 2250
AFPPTVEQPS VTTGPLTSSK APQIPPDSLR NRMLKEQEAN VDDDSCEQAS
2260 2270 2280 2290 2300
LMTSSGKSPL SPDTPSSEEV SYEVNPQPPD PMVLIVPFKA SVIPEETVED
2310 2320 2330 2340 2350
DELKCDLTQR KFTPEEEMFK MAAKIKTFDE MEQDAKDKRD SRKDSEASQT
2360 2370 2380 2390 2400
LVVSDIGQEI ITLFGLVSKH ETSSVDDVGF IESKQASEIA RSVEPIIKVQ
2410 2420 2430 2440 2450
PPSPFPAGIH KSPQTAEDIQ QTMAHSAASS DESAMRRPQS VTEKHTIKPH
2460 2470 2480 2490 2500
PQESHSEKFN QECVKSELAE LNKTASSRSN LAANITDEQK EQSLAKQKIN
2510 2520 2530 2540 2550
ESEEIYSHEM QNQAANFQNV DKLASQEERN VTDEIKGDYM RHAGTSYDDS
2560 2570 2580 2590 2600
CSSSLNIDSM PVIIGQNKET FKPEICIYDD TEEDDGEEEP PKTESRGVTA
2610 2620 2630 2640 2650
KAETDSWNSM REDDEAFAAR VKEEEQKILG LVVDRHSQGA TPDTTPARTP
2660 2670 2680 2690 2700
TEDGTPTSEQ NPFLFQEGKL FEMTRSGAID MTKRSYEEEG FAFYQIEHPI
2710 2720 2730 2740 2750
MEGVAEEGGN ESGGASGDAE KEVGCNLSLQ IKAEEEEDQP KVAADLSVRS
2760 2770 2780 2790 2800
ATAKQSDLSK PKTPIKTDSE KGQGVSEKVE IKSDKVISEG HLISDSGSSD
2810 2820 2830 2840 2850
TVIASIQTAV STVTRSVHSQ QEQESSDSSP EDQHSVIEQP KTPEKKESHG
2860 2870 2880 2890 2900
KLGSKIHTAA SPSTTSKKNM SSSKEEEKPK SRIPVKANSL RSELLEPAKD
2910 2920 2930 2940 2950
KKSKLPIKPQ SRRKSDTDTG PLIPTITKSS KAKSFCESDS SKKPAKKDQN
2960 2970 2980 2990 3000
RPTSTDLSST TKTLPSRLPV RGKPGQPIQT STPAKQKKGR PTHTNKEPVV
3010 3020 3030 3040 3050
FFEEISQEAA KVVESLAQAE KDKQEAAVLS DDESSTIDVS VIENEPFLDM
3060 3070 3080 3090 3100
KMPFPEDPLV IRPRWDNPVE TQMERIPADK VRSQVDPQDE ADRKESRLAV
3110 3120 3130 3140 3150
IANHLGFSWS ELARELEFSD VQINQIRNEN PNSLQDQSHA LIRLWKEREG
3160 3170 3180 3190 3200
KNASENSLMK TLTKINRMDI VHLIETKIIQ SSQDHSSHTY AEIEQTISLD
3210 3220 3230 3240 3250
HSEGFSALQE DMDSPRSGRR ADVSQRRSEL VPVVASIEDL SLNASSLGDS
3260 3270 3280 3290 3300
QKELPDKVTS SVVVGDSTHS FEMVGLRQQF PGTIKQGDDM PEIPPQTVTE
3310 3320 3330 3340 3350
EQYTDEYGNM VVKKITRKVI RKYVSADGVE REEVMLEGPQ QEAVTVDEAD
3360 3370 3380 3390 3400
SFSKVVKRTV VRSGGDQTEV TFSEPLSYAG ATSSKFEEEP VQGRKVSKVV
3410 3420 3430 3440 3450
KTMVVQGDRM EKLIGDPSLS SDLPSAKDDF EKALSYVEGF EKVLLPHLVE
3460 3470 3480 3490 3500
KETVKEDGSV VRRTRMHKTR TQKRTVVKDG EAKQTHLERL EDTAESLRPD
3510 3520 3530
DLQQHLHQLL QRYCTPEPHP PAGQQDKPQP PPAGRPDA
Length:3,538
Mass (Da):388,627
Last modified:February 20, 2007 - v1
Checksum:iBE4AF0003B19A5FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX901910 Genomic DNA No translation available.
CR354563 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000147287; ENSDARP00000114785; ENSDARG00000043313

Similar proteinsi

Entry informationi

Entry nameiA2BIB9_DANRE
AccessioniPrimary (citable) accession number: A2BIB9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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