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Protein

Non-specific serine/threonine protein kinase

Gene

mark4a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-5620912 Anchoring of the basal body to the plasma membrane

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:mark4aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-060531-156 mark4a

Expressioni

Gene expression databases

BgeeiENSDARG00000023914
ExpressionAtlasiA2BHA2 baseline

Structurei

3D structure databases

ProteinModelPortaliA2BHA2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 265Protein kinaseInterPro annotationAdd BLAST252
Domaini284 – 323UBAInterPro annotationAdd BLAST40
Domaini648 – 699KA1InterPro annotationAdd BLAST52

Phylogenomic databases

eggNOGiKOG0586 Eukaryota
ENOG410XNQ0 LUCA
GeneTreeiENSGT00900000140806
HOGENOMiHOG000233025
HOVERGENiHBG052453
OMAiNEITAMY
PhylomeDBiA2BHA2

Family and domain databases

InterProiView protein in InterPro
IPR028375 KA1/Ssp2_C
IPR001772 KA1_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR015940 UBA
PfamiView protein in Pfam
PF02149 KA1, 1 hit
PF00069 Pkinase, 1 hit
PF00627 UBA, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SM00165 UBA, 1 hit
SUPFAMiSSF103243 SSF103243, 1 hit
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50032 KA1, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50030 UBA, 1 hit

Sequencei

Sequence statusi: Complete.

A2BHA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASYSDELPH IGNYRLLKTI GKGNFAKVKL ARHILTGKEV AIKIIDKTQL
60 70 80 90 100
NPTSLQKLFR EVRIMKTLHH PNIVQLFEVI ETEKTLYLVM EYASGGEVFD
110 120 130 140 150
YLVSHGRMKE IEARAKFRQI VSAVHYCHQK NIVHRDLKAE NLLLDADSNI
160 170 180 190 200
KIADFGFSNE FTLGNKLDTF CGSPPYAAPE LFQGKKYDGP EVDIWSLGVI
210 220 230 240 250
LYTLVSGSLP FDGQNLKELR ERVLRGKYRV PFYMSTDCEG ILRRFLVLNP
260 270 280 290 300
SKRCTLEQVM KDKWMNAGHD GDELKPHIEP TEDYSDANRI EIMVGMGFTT
310 320 330 340 350
EEIKDSLLNQ KYNEVTATYL LLGLKTEDGA ESRVSGSMTL PRVRPSPITN
360 370 380 390 400
GTNKHSSSSS SSSSSHSKTQ RSASTYHRQR RHSDFCGPSM PVMHPKRSPT
410 420 430 440 450
SGGDRELRES RMPPRKASCS VMGSRTLPPS SPMVSTANNP NKAEIPDRRK
460 470 480 490 500
EMTATTNNIP GSTMTRRNTY VCTDRSSTDR HSLLQNGKDN SIVGAGASSS
510 520 530 540 550
SSSGERCRLT RGSTIRSTFH GGQLRDRVPP TYGPPPTSPT LSHDAGALPA
560 570 580 590 600
NARSRATSNL FSKLTSKLTR RVSNESEGVS RSSVTGGHLS GDQKASEPWG
610 620 630 640 650
GGGGWDVRAR LSRPPRAPAE VVLALREAAR GCGCQVRHAG PFLLCCSHGA
660 670 680 690
AGSKVAFQAE VCQLSVGPAE ANGVRYTRLW GAPLAFRHIA SQISKEVEL
Length:699
Mass (Da):76,947
Last modified:February 20, 2007 - v1
Checksum:iC714FC534F28C665
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX547938 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000146854; ENSDARP00000121243; ENSDARG00000023914

Similar proteinsi

Entry informationi

Entry nameiA2BHA2_DANRE
AccessioniPrimary (citable) accession number: A2BHA2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: June 20, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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