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UniProtKB - A2BGS8 (A2BGS8_DANRE)
Protein
Submitted name:
Transient receptor potential cation channel, subfamily M, member 3
Gene
trpm3
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- calcium activated cation channel activity Source: InterPro
- cation channel activity Source: GO_Central
GO - Biological processi
- cation transmembrane transport Source: GO_Central
- detection of temperature stimulus Source: InterPro
- protein tetramerization Source: InterPro
- sensory perception of temperature stimulus Source: InterPro
Keywordsi
Biological process | Ion transportARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: Transient receptor potential cation channel, subfamily M, member 3Imported |
Gene namesi | Name:trpm3Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-060531-95, trpm3 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 888 – 904 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 951 – 969 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 981 – 999 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 1020 – 1040 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1098 – 1123 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSDARG00000039181, Expressed in choroid plexus and 20 other tissues |
ExpressionAtlasi | A2BGS8, baseline |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 93 – 358 | LSDAT_eukInterPro annotationAdd BLAST | 266 | |
Domaini | 890 – 1132 | Ion_transInterPro annotationAdd BLAST | 243 | |
Domaini | 1224 – 1278 | TRPM_tetraInterPro annotationAdd BLAST | 55 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 41 – 61 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 1314 – 1340 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 1379 – 1404 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 1578 – 1632 | DisorderedSequence analysisAdd BLAST | 55 | |
Regioni | 1676 – 1734 | DisorderedSequence analysisAdd BLAST | 59 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1227 – 1247 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1598 – 1622 | Basic and acidic residuesSequence analysisAdd BLAST | 25 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3614, Eukaryota |
GeneTreei | ENSGT00940000157366 |
InParanoidi | A2BGS8 |
OMAi | YTHIPEC |
PhylomeDBi | A2BGS8 |
TreeFami | TF314204 |
Family and domain databases
Gene3Di | 1.20.5.1010, 1 hit |
InterProi | View protein in InterPro IPR005821, Ion_trans_dom IPR029583, TRPM3 IPR041491, TRPM_SLOG IPR032415, TRPM_tetra IPR037162, TRPM_tetra_sf |
PANTHERi | PTHR13800:SF7, PTHR13800:SF7, 2 hits |
Pfami | View protein in Pfam PF00520, Ion_trans, 1 hit PF18139, LSDAT_euk, 1 hit PF16519, TRPM_tetra, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A2BGS8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
AQKSWIERAF SKRECVHIIV STKDHHRCCC GRLIGQHVGL PPSISSNQNE
60 70 80 90 100
KSERVPKNDS LSEKWSISKH TQLSPTDAFG TIEFQGGGHS NKAMYVRVSY
110 120 130 140 150
DTKPDLLLHL MTKEWQLELP KLLISVHGGL QNFELQPKLK QVFGKGLIKA
160 170 180 190 200
AMTTGAWIFT GGVNTGVIRH VGDALKDHAS KSRGKICTIG IAPWGIVENQ
210 220 230 240 250
EDLVGKDVVR PYQTMSNPLS KLTVLNSLHS HFILADNGTT GKYGAEVKLR
260 270 280 290 300
RQLEKHISLQ KINTRIGQGV PVVALIVEGG PNVISIVLEY LRDTPPVPVV
310 320 330 340 350
VCDGSGRASD ILAFGHKYSE EGGIINESLR DQLLVTIQKT FTYSRTQAQH
360 370 380 390 400
LFIILMECMK KKELITVFRM GSEGHQDIDL AILTALLKGA NASAPDQLSL
410 420 430 440 450
ALAWNRVDIA RSQIFIYGQQ WPVGSLEQSM LDALVLDRVD FVKLLIENGV
460 470 480 490 500
SMHRFLTLSR LEELYNTRHG PSNTLYHLVR DVKKGNLPPD YRISLIDIGL
510 520 530 540 550
VIEYLMGGAY RCNYTRKRFR TLYHNLFGPK RPKALKLLGM EDDMPIRRGR
560 570 580 590 600
QKTTRKREEE VDIDLDDPEI NHFPFPFHEL MVWAVLMKRQ KMALFFWQHG
610 620 630 640 650
EEAMAKALVA CKLCKAMAHE ASENDMVDDI SQELNQNSRE FGQLAVELLD
660 670 680 690 700
QSYKQDEQMA MKLLTYELKN WSNATCLQLA VAAKHRDFIA HTCSQMLLTD
710 720 730 740 750
MWMGRLRMRK NSGLKVILGL LLPPSILSLE FKNKDEMSYM PQDQDTYLQE
760 770 780 790 800
KDVDEPEKQA KEKEEEDMEF TVRSYCETQY NSVAMLGNVS SEASRKKQVE
810 820 830 840 850
EVQNRHRLIP LGRKIYEFYN APIVKFWFHT KVHDCHRLIP VGRKIKVQDR
860 870 880 890 900
NLLILVGHKM YEFYNNPFIK FWFCMVNSII YYTKTNCTLA YVGYLMLFNY
910 920 930 940 950
IVLVKMDLWP SPQEWIVIAY IFTNGIEKMR EILMSEPGKL LQKVKVWLQE
960 970 980 990 1000
YWNITDLMAI LIFSIGMVLR LQDPPLMSYG RVIYCVNIIY WYIRLLDIFG
1010 1020 1030 1040 1050
VNKYLGPYVM MIGKMMIDMM YFVIIMLVVL MSFGVARQAI LNPNEDPSWM
1060 1070 1080 1090 1100
LARNIFFMPY WMIYGEVFAD QIDPPCGQNI TTEEGVVMPL PPCKTGAWIV
1110 1120 1130 1140 1150
PAIMACYLLV ANILLVNLLI AVFNNTFFEV KSISNQVWKF QRYQLIMTFH
1160 1170 1180 1190 1200
ERPVLPPPLI IFSHITMVLK HLCCRWRKHD EDERDYGLKL FITEDELKKV
1210 1220 1230 1240 1250
HDFEEQCMEE YFREKDDRFN SSNDERIRVT SERVENMAMR LEEVNEREHF
1260 1270 1280 1290 1300
MKASLQTVDI RLAQMEEMIG RIAVALERVA GMDRGEVNKA RSRTSSDCTD
1310 1320 1330 1340 1350
TNYILRQSSF NSQEGNSYRL QESLEQGGDE SISPTSPTAL APRVRSHSFY
1360 1370 1380 1390 1400
VSHSSKDRSG ADRGEGFFKD KLFSLHRANS SQSVSSGAGP KESKPTPLNT
1410 1420 1430 1440 1450
LSVQQQLRPS SCIDIYVSAS EDVPPTESFL DSVRTVPTLA RDSSLHSEIM
1460 1470 1480 1490 1500
EAVLSGGRDC SGRAGGSERQ SDGTVLFEDS AAADLSLCSA HLLPDSLPPW
1510 1520 1530 1540 1550
DLDPSPPPSA GVLERSKSSR FLSTAGPLFL DEPHLVKSHS LMFTSRGYYG
1560 1570 1580 1590 1600
GMGVQVKAAE YTSITDCIDT RCVSTPYPVP ERSDSPGGSF TFDKPQDLGV
1610 1620 1630 1640 1650
SHPERDAELS HAESDLEEPA EGSGDTCKVG QSSSSGVIGA DLGLGLALGP
1660 1670 1680 1690 1700
FCSPISRLER ANSCSSSEES HSNIYSRKSF SISERMDKGR GSSRNPFQKA
1710 1720 1730
RTGARLEGKT DSLSMRKMAK PSAFRSFDSR HNYT
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF1QYX6 | F1QYX6_DANRE | Transient receptor potential cation... | trpm3 | 1,583 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 1734 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323080 Genomic DNA No translation available. BX511001 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000147188; ENSDARP00000123466; ENSDARG00000039181 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323080 Genomic DNA No translation available. BX511001 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000123466 |
Proteomic databases
PaxDbi | A2BGS8 |
PeptideAtlasi | A2BGS8 |
Genome annotation databases
Ensembli | ENSDART00000147188; ENSDARP00000123466; ENSDARG00000039181 |
Organism-specific databases
ZFINi | ZDB-GENE-060531-95, trpm3 |
Phylogenomic databases
eggNOGi | KOG3614, Eukaryota |
GeneTreei | ENSGT00940000157366 |
InParanoidi | A2BGS8 |
OMAi | YTHIPEC |
PhylomeDBi | A2BGS8 |
TreeFami | TF314204 |
Gene expression databases
Bgeei | ENSDARG00000039181, Expressed in choroid plexus and 20 other tissues |
ExpressionAtlasi | A2BGS8, baseline |
Family and domain databases
Gene3Di | 1.20.5.1010, 1 hit |
InterProi | View protein in InterPro IPR005821, Ion_trans_dom IPR029583, TRPM3 IPR041491, TRPM_SLOG IPR032415, TRPM_tetra IPR037162, TRPM_tetra_sf |
PANTHERi | PTHR13800:SF7, PTHR13800:SF7, 2 hits |
Pfami | View protein in Pfam PF00520, Ion_trans, 1 hit PF18139, LSDAT_euk, 1 hit PF16519, TRPM_tetra, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A2BGS8_DANRE | |
Accessioni | A2BGS8Primary (citable) accession number: A2BGS8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 20, 2007 |
Last sequence update: | February 20, 2007 | |
Last modified: | January 19, 2022 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |