marveld2b

Functionⁱ

GO - Biological processⁱ

cell-cell junction organization Source: InterPro
sensory perception of sound Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MARVEL domain-containing 2bImported
Gene namesⁱ	Name:marveld2bImported
Organismⁱ	Danio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifierⁱ	7955 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Otomorpha › Ostariophysi › Otophysi › Cypriniphysae › Cypriniformes › Cyprinoidea › Cyprinidae › Danio
Proteomesⁱ	UP000000437 Componentⁱ: Chromosome 5

Organism-specific databases

ZFINⁱ	ZDB-GENE-050208-54 marveld2b

ZFINⁱ

ZDB-GENE-050208-54 marveld2b

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	201 – 225	HelicalSequence analysisAdd BLAST	25
Transmembraneⁱ	265 – 289	HelicalSequence analysisAdd BLAST	25
Transmembraneⁱ	301 – 322	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	353 – 376	HelicalSequence analysisAdd BLAST	24

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	A2BGQ4

PaxDbⁱ

A2BGQ4

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSDARG00000061651 Expressed in 17 organ(s), highest expression level in mature ovarian follicle

Bgeeⁱ

ENSDARG00000061651 Expressed in 17 organ(s), highest expression level in mature ovarian follicle

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	7955.ENSDARP00000122328

STRINGⁱ

7955.ENSDARP00000122328

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A2BGQ4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	197 – 377	MARVELInterPro annotationAdd BLAST		181

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	484 – 504	Sequence analysisAdd BLAST		21
Coiled coilⁱ	537 – 557	Sequence analysisAdd BLAST		21

Keywords - Domainⁱ

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG4796 Eukaryota ENOG410ZNGU LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074378
HOGENOMⁱ	HOG000155323
HOVERGENⁱ	HBG079727
OMAⁱ	PLTECSI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G04ZP
PhylomeDBⁱ	A2BGQ4
TreeFamⁱ	TF326161

Family and domain databases

InterProⁱ	View protein in InterPro IPR031176 ELL/occludin IPR008253 Marvel IPR031177 MARVELD2 IPR010844 Occludin_ELL
PANTHERⁱ	PTHR23288 PTHR23288, 1 hit PTHR23288:SF3 PTHR23288:SF3, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01284 MARVEL, 1 hit PF07303 Occludin_ELL, 1 hit
PROSITEⁱ	View protein in PROSITE PS51225 MARVEL, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A2BGQ4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSFGNGSASR FDRVRDMPHY DQVPIGSMPW GQQPPYPLGG GVAASSFESL 
        60         70         80         90        100
PPPPLPENPP VGPEFYPSDV EDQVDDAMDI KPIRRFIPDS VKNFFRASVN 
       110        120        130        140        150
RGSKKLTFPL PPPPIDGNTT SQGVPCSPPH SRAPSPTAPS SYLDPYGGSG 
       160        170        180        190        200
GSYTSRKEQA MLLGEPLESV SGRSLQTAMT YSEKVEEYNQ RYAYMKSWAG 
       210        220        230        240        250
LLRILGCVEL LLGAAVFACV CAYVHKDNEW FNMYGYSMHQ VYGGASMGGM 
       260        270        280        290        300
YGGYGSSYSG PLTPFVLVVA GVAWIVTVII LILGITMYYR TILLDSSWWP 
       310        320        330        340        350
ITECVVNVAL GLLYLAAAIV YVRDTLRGGL CYYQQFTVGP NAGFCRTEAG 
       360        370        380        390        400
QNAAIIFLFV NMLLYLVGAI VCLKMWRHEA ARMRRERLEQ DMKSDGLPLN 
       410        420        430        440        450
MIGAGSSVSV PIQSAPVMTK LETFDGMPDH PAMMEPEILR GHIPAGHIPK 
       460        470        480        490        500
PLVIADYVAK YPTIRTDEER ERYKAVFNDQ YAEYKELHAE VQVLTQKFEE 
       510        520        530        540        550
MDNLMRNLPQ RPSSQMEQER ISSIVQEYNR KKADPTYQEK RERCEYLKNK 
       560        570 
LAHIKQKIQE YDKIMDWNDG YS

Length:572

Mass (Da):64,051

Last modified:February 20, 2007 - v1

Checksum:ⁱE1BF248A609985D9

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX510923 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001119878.1, NM_001126406.1
UniGeneⁱ	Dr.90900

Genome annotation databases

Ensemblⁱ	ENSDART00000137178; ENSDARP00000122328; ENSDARG00000061651
GeneIDⁱ	563122
KEGGⁱ	dre:563122

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
A2BGQ4	Tricellulin (Fragment)		ONCMY		569	UniRef50_M9YY17
MARVEL domain-containing protein 2		SALSA		575
MARVEL domain containing 2b		ORYLA		554
MARVEL domain-containing 2a		DANRE		545
Uncharacterized protein		CHICK		506
+249

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX510923 Genomic DNA No translation available.
RefSeqⁱ	NP_001119878.1, NM_001126406.1
UniGeneⁱ	Dr.90900

3D structure databases

ProteinModelPortalⁱ	A2BGQ4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	7955.ENSDARP00000122328

STRINGⁱ

7955.ENSDARP00000122328

Proteomic databases

PaxDbⁱ	A2BGQ4

PaxDbⁱ

A2BGQ4

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSDART00000137178; ENSDARP00000122328; ENSDARG00000061651
GeneIDⁱ	563122
KEGGⁱ	dre:563122

Organism-specific databases

CTDⁱ	563122
ZFINⁱ	ZDB-GENE-050208-54 marveld2b

Phylogenomic databases

eggNOGⁱ	KOG4796 Eukaryota ENOG410ZNGU LUCA
GeneTreeⁱ	ENSGT00550000074378
HOGENOMⁱ	HOG000155323
HOVERGENⁱ	HBG079727
OMAⁱ	PLTECSI
OrthoDBⁱ	EOG091G04ZP
PhylomeDBⁱ	A2BGQ4
TreeFamⁱ	TF326161

Gene expression databases

Bgeeⁱ	ENSDARG00000061651 Expressed in 17 organ(s), highest expression level in mature ovarian follicle

Bgeeⁱ

ENSDARG00000061651 Expressed in 17 organ(s), highest expression level in mature ovarian follicle

Family and domain databases

InterProⁱ	View protein in InterPro IPR031176 ELL/occludin IPR008253 Marvel IPR031177 MARVELD2 IPR010844 Occludin_ELL
PANTHERⁱ	PTHR23288 PTHR23288, 1 hit PTHR23288:SF3 PTHR23288:SF3, 1 hit
Pfamⁱ	View protein in Pfam PF01284 MARVEL, 1 hit PF07303 Occludin_ELL, 1 hit
PROSITEⁱ	View protein in PROSITE PS51225 MARVEL, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A2BGQ4_DANRE
Accessionⁱ	A2BGQ4Primary (citable) accession number: A2BGQ4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 20, 2007
	Last sequence update:	February 20, 2007
	Last modified:	September 12, 2018
	This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2BGQ4 (A2BGQ4_DANRE)

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MARVEL domain-containing 2b

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Topology

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ