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Protein

Calcium-binding and coiled-coil domain-containing protein 1

Gene

calcoco1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May function as a coactivator for aryl hydrocarbon and nuclear receptors.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Calcium-binding and coiled-coil domain-containing protein 1
Gene namesi
Name:calcoco1
ORF Names:si:dkey-148f24.4
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Organism-specific databases

ZFINiZDB-GENE-030131-6911 calcoco1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089031 – 640Calcium-binding and coiled-coil domain-containing protein 1Add BLAST640

Proteomic databases

PaxDbiA2BGD5
PRIDEiA2BGD5

Expressioni

Gene expression databases

BgeeiENSDARG00000036695 Expressed in 25 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiA2BGD5 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000093924

Structurei

3D structure databases

SMRiA2BGD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili141 – 212Sequence analysisAdd BLAST72
Coiled coili246 – 346Sequence analysisAdd BLAST101
Coiled coili424 – 510Sequence analysisAdd BLAST87

Sequence similaritiesi

Belongs to the CALCOCO family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IHKH Eukaryota
ENOG410ZVZ6 LUCA
GeneTreeiENSGT00530000063216
HOGENOMiHOG000111282
HOVERGENiHBG057207
InParanoidiA2BGD5
PhylomeDBiA2BGD5
TreeFamiTF329501

Family and domain databases

InterProiView protein in InterPro
IPR012852 CALCOCO1-like
PfamiView protein in Pfam
PF07888 CALCOCO1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A2BGD5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKTWRVEFR NVGSCYFPQS RVDCHYTINP QHTWASNDWI GLFKVGWSSV
60 70 80 90 100
KEYHTFVWAV APSSYKEGTS VNCCVNFQAS YLPGPSAQQY QFVYVDGKGE
110 120 130 140 150
ICSCSAAFTF SAPKPLEELV TLEEEGQGEE VGEDMLLVIP RAQLLQSRLQ
160 170 180 190 200
ECLKERAELL QALEAADQNV EREKGRRERD RGSWEHTRKE LERKIDDLKE
210 220 230 240 250
EVREYREKVE DMKKKQKEVE DLGEALTEEK RALLAQKEAN EQRIRELEED
260 270 280 290 300
IKILTQRGLE RETDLERMRE RAKKSAAQKR EDEDEHKNLK LKMEQTEKEL
310 320 330 340 350
HSLSAEFQSL RSSLAQRDTH ALQLRDTITT LTHKLNSAHR KEAANELALN
360 370 380 390 400
ELRSVQERLN VSEHCVETLR GELRDMVAQR DSAHAELHQA RLQAAQLTLQ
410 420 430 440 450
LADASLALRE GRANWAQERE TLQQNAEIDK VRLERQNDEI QQKEEMLQKA
460 470 480 490 500
RMEREKAVVE LGREKDCNRE LKASLRVAQK EKEQLQTEIQ EVMEYSRQLE
510 520 530 540 550
RRLEVLSDCK WSETALLQSS RAESPLLSDS EDENPEALQD THSSGPLNHY
560 570 580 590 600
SLCEQPQSDL LLPATPPPSP RHPSTVVISQ PAPLSSPHQP SARSHTHSSE
610 620 630 640
SEEEYEAALS GGHSSGEETA LLLPDNRDTT LGELAESPLW
Length:640
Mass (Da):73,425
Last modified:February 20, 2007 - v1
Checksum:iE2DCCF96472B0BC6
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4IFJ0A0A0R4IFJ0_DANRE
Calcium-binding and coiled-coil dom...
calcoco1a
651Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX465864 Genomic DNA Translation: CAM14487.1
RefSeqiNP_001103636.1, NM_001110166.1
UniGeneiDr.74551

Genome annotation databases

EnsembliENSDART00000103150; ENSDARP00000093924; ENSDARG00000036695
GeneIDi334971
KEGGidre:334971

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX465864 Genomic DNA Translation: CAM14487.1
RefSeqiNP_001103636.1, NM_001110166.1
UniGeneiDr.74551

3D structure databases

SMRiA2BGD5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000093924

Proteomic databases

PaxDbiA2BGD5
PRIDEiA2BGD5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000103150; ENSDARP00000093924; ENSDARG00000036695
GeneIDi334971
KEGGidre:334971

Organism-specific databases

CTDi334971
ZFINiZDB-GENE-030131-6911 calcoco1a

Phylogenomic databases

eggNOGiENOG410IHKH Eukaryota
ENOG410ZVZ6 LUCA
GeneTreeiENSGT00530000063216
HOGENOMiHOG000111282
HOVERGENiHBG057207
InParanoidiA2BGD5
PhylomeDBiA2BGD5
TreeFamiTF329501

Miscellaneous databases

PROiPR:A2BGD5

Gene expression databases

BgeeiENSDARG00000036695 Expressed in 25 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiA2BGD5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR012852 CALCOCO1-like
PfamiView protein in Pfam
PF07888 CALCOCO1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCACO1_DANRE
AccessioniPrimary (citable) accession number: A2BGD5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: February 20, 2007
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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