Condensin complex subunit 2

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• chromatin binding Source: GO_Central
• DNA topoisomerase (ATP-hydrolyzing) activator activity Source: GO_Central
• DNA topoisomerase binding Source: GO_Central

GO - Biological processⁱ

• cell division Source: UniProtKB-KW
• mitotic chromosome condensation Source: GO_Central
• mitotic sister chromatid segregation Source: ZFIN <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 19586528

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• DNA topoisomerase binding Source: GO_Central

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MSAFSTPTAR QRQWSSPALG HKAALSTTST PLLDNIQGND DEQERRQRRR 
        60         70         80         90        100
SRVIDLHGVN DSSINEAGTH SSAGTPAAVP KLSSAQISEH YSTCIKLSTE 
       110        120        130        140        150
NKITTKNAFG LHLIDYMADI LKEKDSELNF KVAAGTLDAS TKIYAVRVDA 
       160        170        180        190        200
VHADAYRVLG GLGSETKPKE SQDGDDETEA AEGSQGEQVA AKQTKKRPPK 
       210        220        230        240        250
KTVEQNLSNI NLSESEMKCE VDPMFQRMAA SFDENSTAGV FLSVLFSEDS 
       260        270        280        290        300
CCELRFPSHM TLLKSQLPPV QVSHQNVPAS PFTGHLKTLE DRPICPSLED 
       310        320        330        340        350
FSFTRWTPEQ TTNLNQLLEK MKQGEHAFDV NADIEPDEDD APDFGDNFDA 
       360        370        380        390        400
DVDEGRPGDN EEFKEHKEAC SKSPQNGRGV IPIGEVDIAT MCLQLSDQPR 
       410        420        430        440        450
EYSYFSPRTM ATWVGPGYWL FKPGHKQDQK PDKEPRKRAP KNPLIIDFKA 
       460        470        480        490        500
DINFHNYFKT TRAATTISKS ALNTSNKKTT LPADFQYPPS NLSQLNLKPS 
       510        520        530        540        550
NTLSAEGKKR LSGELSEDIG EYNYNNANDT ANFCPGLQEG DSEDAEGFAG 
       560        570        580        590        600
SDDSQTDRPT PFSLDTDDIS TYGEDCLVPE PHKLNIIEIN YARTAKKMDM 
       610        620        630        640        650
KKLKTTMWGL LTESPEKTAK QVESEDTTEV PGEKSFSQSI RNLVQRLPSA 
       660        670        680        690
MATNLSVPLA FVALLHLANE KNLELHKIDG MTDIIIKQGH            

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ