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Protein

Condensin complex subunit 2

Gene

ncaph

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • cell division Source: UniProtKB-KW
  • mitotic chromosome condensation Source: GO_Central
  • mitotic sister chromatid segregation Source: ZFIN

Keywordsi

Biological processCell cycle, Cell division, DNA condensationUniRule annotation, MitosisUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-2514853 Condensation of Prometaphase Chromosomes

Names & Taxonomyi

Protein namesi
Recommended name:
Condensin complex subunit 2UniRule annotation
Gene namesi
Name:ncaphImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-070112-652 ncaph

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiA2BG39
PeptideAtlasiA2BG39

Expressioni

Gene expression databases

BgeeiENSDARG00000061468 Expressed in 33 organ(s), highest expression level in cleaving embryo

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000082118

Family & Domainsi

Sequence similaritiesi

Belongs to the CND2 (condensin subunit 2) family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2328 Eukaryota
COG5229 LUCA
GeneTreeiENSGT00390000004149
HOVERGENiHBG036823
InParanoidiA2BG39
OMAiQALQKNW
OrthoDBiEOG091G01HE
TreeFamiTF105678

Family and domain databases

InterProiView protein in InterPro
IPR022816 Condensin_barren_su2
PANTHERiPTHR13108 PTHR13108, 1 hit
PfamiView protein in Pfam
PF05786 Cnd2, 1 hit
PIRSFiPIRSF017126 Condensin_H, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A2BG39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAFSTPTAR QRQWSSPALG HKAALSTTST PLLDNIQGND DEQERRQRRR
60 70 80 90 100
SRVIDLHGVN DSSINEAGTH SSAGTPAAVP KLSSAQISEH YSTCIKLSTE
110 120 130 140 150
NKITTKNAFG LHLIDYMADI LKEKDSELNF KVAAGTLDAS TKIYAVRVDA
160 170 180 190 200
VHADAYRVLG GLGSETKPKE SQDGDDETEA AEGSQGEQVA AKQTKKRPPK
210 220 230 240 250
KTVEQNLSNI NLSESEMKCE VDPMFQRMAA SFDENSTAGV FLSVLFSEDS
260 270 280 290 300
CCELRFPSHM TLLKSQLPPV QVSHQNVPAS PFTGHLKTLE DRPICPSLED
310 320 330 340 350
FSFTRWTPEQ TTNLNQLLEK MKQGEHAFDV NADIEPDEDD APDFGDNFDA
360 370 380 390 400
DVDEGRPGDN EEFKEHKEAC SKSPQNGRGV IPIGEVDIAT MCLQLSDQPR
410 420 430 440 450
EYSYFSPRTM ATWVGPGYWL FKPGHKQDQK PDKEPRKRAP KNPLIIDFKA
460 470 480 490 500
DINFHNYFKT TRAATTISKS ALNTSNKKTT LPADFQYPPS NLSQLNLKPS
510 520 530 540 550
NTLSAEGKKR LSGELSEDIG EYNYNNANDT ANFCPGLQEG DSEDAEGFAG
560 570 580 590 600
SDDSQTDRPT PFSLDTDDIS TYGEDCLVPE PHKLNIIEIN YARTAKKMDM
610 620 630 640 650
KKLKTTMWGL LTESPEKTAK QVESEDTTEV PGEKSFSQSI RNLVQRLPSA
660 670 680 690
MATNLSVPLA FVALLHLANE KNLELHKIDG MTDIIIKQGH
Length:690
Mass (Da):76,357
Last modified:February 20, 2007 - v1
Checksum:i558D2CA11176DFC3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A1L231A1L231_DANRE
Condensin complex subunit 2
ncaph zgc:158618
690Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323557 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000087684; ENSDARP00000082118; ENSDARG00000061468
ENSDART00000181434; ENSDARP00000147180; ENSDARG00000061468

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323557 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000082118

Proteomic databases

PaxDbiA2BG39
PeptideAtlasiA2BG39

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000087684; ENSDARP00000082118; ENSDARG00000061468
ENSDART00000181434; ENSDARP00000147180; ENSDARG00000061468

Organism-specific databases

ZFINiZDB-GENE-070112-652 ncaph

Phylogenomic databases

eggNOGiKOG2328 Eukaryota
COG5229 LUCA
GeneTreeiENSGT00390000004149
HOVERGENiHBG036823
InParanoidiA2BG39
OMAiQALQKNW
OrthoDBiEOG091G01HE
TreeFamiTF105678

Enzyme and pathway databases

ReactomeiR-DRE-2514853 Condensation of Prometaphase Chromosomes

Gene expression databases

BgeeiENSDARG00000061468 Expressed in 33 organ(s), highest expression level in cleaving embryo

Family and domain databases

InterProiView protein in InterPro
IPR022816 Condensin_barren_su2
PANTHERiPTHR13108 PTHR13108, 1 hit
PfamiView protein in Pfam
PF05786 Cnd2, 1 hit
PIRSFiPIRSF017126 Condensin_H, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2BG39_DANRE
AccessioniPrimary (citable) accession number: A2BG39
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: September 12, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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