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Protein

Olfactory receptor

Gene

Olfr1157

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • G protein-coupled receptor activity Source: UniProtKB-KW
  • odorant binding Source: GO_Central
  • olfactory receptor activity Source: MGI

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr1157Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3030991 Olfr1157

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 49HelicalUniRule annotationAdd BLAST24
Transmembranei61 – 83HelicalUniRule annotationAdd BLAST23
Transmembranei95 – 120HelicalUniRule annotationAdd BLAST26
Transmembranei140 – 164HelicalUniRule annotationAdd BLAST25
Transmembranei209 – 226HelicalUniRule annotationAdd BLAST18
Transmembranei238 – 261HelicalUniRule annotationAdd BLAST24
Transmembranei273 – 292HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiA2AVC4
PRIDEiA2AVC4

PTM databases

PhosphoSitePlusiA2AVC4

Expressioni

Gene expression databases

BgeeiENSMUSG00000075143 Expressed in 2 organ(s), highest expression level in lung

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097429

Structurei

3D structure databases

ProteinModelPortaliA2AVC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410J9CC Eukaryota
ENOG4111BEJ LUCA
GeneTreeiENSGT00550000074428
HOGENOMiHOG000041364
HOVERGENiHBG017625
InParanoidiA2AVC4
KOiK04257
OMAiELASCCY
OrthoDBiEOG091G0AZH
PhylomeDBiA2AVC4
TreeFamiTF352753

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A2AVC4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDEENCSTVA QFILLGFSDV PELSGVLSLL FLLIYGVTAL ANLGMTALIQ
60 70 80 90 100
VSSQLHTPMY FFLSHLSFVD FCYSSVIVPK MLANIFNKDK AISSLACMVQ
110 120 130 140 150
FYLFCTCVVT EVFLLAVMAY DRFVAICNPL LYTAIMSSNL RMILVSGCYL
160 170 180 190 200
CASMCSLIHL CLALEIPSFK SNVINHFFCD LPPLLSLACS DVTVNKVLLF
210 220 230 240 250
VVATFNESFS IVVIFTSYLF ILITILRMRS VEGRRKAFST CASHLTVIIV
260 270 280 290 300
FHGTILSIYC SSTSDNSGDA DKVATVFYTV VIPMLNPLIY SLRNKDVKGA
310
LRKVVNSKIY SQ
Length:312
Mass (Da):34,567
Last modified:February 20, 2007 - v1
Checksum:iA16CFE45EF4B8D0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929424 Genomic DNA No translation available.
BX649203 Genomic DNA No translation available.
RefSeqiNP_667060.2, NM_146849.2
UniGeneiMm.223270

Genome annotation databases

EnsembliENSMUST00000099841; ENSMUSP00000097429; ENSMUSG00000075143
GeneIDi258846
KEGGimmu:258846
UCSCiuc008kpa.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929424 Genomic DNA No translation available.
BX649203 Genomic DNA No translation available.
RefSeqiNP_667060.2, NM_146849.2
UniGeneiMm.223270

3D structure databases

ProteinModelPortaliA2AVC4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097429

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSitePlusiA2AVC4

Proteomic databases

PaxDbiA2AVC4
PRIDEiA2AVC4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000099841; ENSMUSP00000097429; ENSMUSG00000075143
GeneIDi258846
KEGGimmu:258846
UCSCiuc008kpa.2 mouse

Organism-specific databases

CTDi258846
MGIiMGI:3030991 Olfr1157

Phylogenomic databases

eggNOGiENOG410J9CC Eukaryota
ENOG4111BEJ LUCA
GeneTreeiENSGT00550000074428
HOGENOMiHOG000041364
HOVERGENiHBG017625
InParanoidiA2AVC4
KOiK04257
OMAiELASCCY
OrthoDBiEOG091G0AZH
PhylomeDBiA2AVC4
TreeFamiTF352753

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000075143 Expressed in 2 organ(s), highest expression level in lung

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2AVC4_MOUSE
AccessioniPrimary (citable) accession number: A2AVC4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 7, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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