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Protein

Centrosomal protein of 152 kDa

Gene

Cep152

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (By similarity). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (By similarity). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles (PubMed:24240477). Overexpression of cep152 can drive amplification of centrioles.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-2565942 Regulation of PLK1 Activity at G2/M Transition
R-MMU-380259 Loss of Nlp from mitotic centrosomes
R-MMU-380270 Recruitment of mitotic centrosome proteins and complexes
R-MMU-380320 Recruitment of NuMA to mitotic centrosomes
R-MMU-5620912 Anchoring of the basal body to the plasma membrane
R-MMU-8854518 AURKA Activation by TPX2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Centrosomal protein of 152 kDa
Short name:
Cep152
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cep152
Synonyms:Kiaa0912
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2139083 Cep152

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004248201 – 1736Centrosomal protein of 152 kDaAdd BLAST1736

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1277PhosphothreonineBy similarity1
Modified residuei1714N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A2AUM9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2AUM9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A2AUM9

PeptideAtlas

More...
PeptideAtlasi
A2AUM9

PRoteomics IDEntifications database

More...
PRIDEi
A2AUM9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2AUM9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A2AUM9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000068394 Expressed in 206 organ(s), highest expression level in ventricular system choroidal fissure

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2AUM9 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminus) with PLK4; the interaction is mutally exclusive with a PLK4:CEP192 interaction. Interacts (via C-terminus) with CENPJ (via-N-terminus). Interacts with CINP. Interacts with CDK5RAP2, WDR62, CEP63 and CEP131. CEP63, CDK5RAP2, CEP152, WDR62 are proposed to form a stepwise assembled complex at the centrosome forming a ring near parental centrioles (By similarity). Interacts with DEUP1; this interaction recruits CEP152 to the deuterosome. The interactions with CEP63 and DEUP1 are mutually exclusive (PubMed:24240477).By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
221186, 81 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1160 CEP152-PLK4 complex

Database of interacting proteins

More...
DIPi
DIP-56915N

Protein interaction database and analysis system

More...
IntActi
A2AUM9, 85 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000087208

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2AUM9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 60Interaction with PLK4By similarityAdd BLAST60

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili228 – 481Sequence analysisAdd BLAST254
Coiled coili552 – 651Sequence analysisAdd BLAST100
Coiled coili692 – 776Sequence analysisAdd BLAST85
Coiled coili835 – 868Sequence analysisAdd BLAST34
Coiled coili950 – 1075Sequence analysisAdd BLAST126
Coiled coili1205 – 1315Sequence analysisAdd BLAST111

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CEP152 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGHC Eukaryota
ENOG410XQAW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153127

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111522

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG096403

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2AUM9

KEGG Orthology (KO)

More...
KOi
K16728

Identification of Orthologs from Complete Genome Data

More...
OMAi
QSRREWT

Database of Orthologous Groups

More...
OrthoDBi
243447at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332017

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029598 Cep152

The PANTHER Classification System

More...
PANTHERi
PTHR10337:SF6 PTHR10337:SF6, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A2AUM9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLEFGSVAL QTQNEDEEFD KEDFEREKEL QQLLTDLPHD MLDDELSSPE
60 70 80 90 100
RHDSDCSMDG RAAEPHPSEH LERKWIERDI LPKPHSMNCG NGWEENRSKT
110 120 130 140 150
EDQHLGYHPG EGGDEGGSGY SPPGKREQAD LYRLPEDFRP YTGGSKQAAS
160 170 180 190 200
VITFSDPQRD NFQQFGLSRG PSCGALEPYK AVYKPYRNSS VQKNSSPAQE
210 220 230 240 250
VAASDMFEGL QQQFLGANET DSAENIHIIQ LQVLNKAKER QLDSLVEKLK
260 270 280 290 300
DSERQVRYLS HQLLIVQDEK DGLALSLRES QQLFQNGKER EMQLEAQIAA
310 320 330 340 350
LEAQVEAFRV SEEKLTKKLR TTEITLESLK QQLVELHHSE SLQRAREHHE
360 370 380 390 400
SIVASLTQKH EEQVSSLQKN LDATITALQE QESICTRLKD HVQQLERNQE
410 420 430 440 450
AVRLEKTELI NRLTRSLEDS QKQCAHLLQS GSVQEVAQLQ LQLQQAQKAH
460 470 480 490 500
VLSESMNKAL QEELTELKDE ISLYESAAEL GVLPGDSEGD LSIELTESCV
510 520 530 540 550
DLGIKKVNWK QSKANRVTQQ ESPDEDPSKD ELILKLKTQV QRLLTSNSVK
560 570 580 590 600
RHLVSQLQSD LRECRETMEA FQQSKDGDSG METKTDTSEK TTKQLWLESS
610 620 630 640 650
EAINREDILQ LKNEVQVLQK QNQELKEAEE KLRSTNQDLC NQMRQMVQEF
660 670 680 690 700
DHDKQEAVAR CERTYQQHHE AMKAQIRESL LAKHAVEKQH LLEVYEGTQS
710 720 730 740 750
QLRSDLDKMN KEMAAVQECY LEVCREKDGL ESTLRKTMEK AQEQKRQLLE
760 770 780 790 800
AREEYVRKLK LELEEKYQET LKTERQSWLQ EQAAGATQQA EKESRQKLIQ
810 820 830 840 850
QLEKEWQSKL DDSLAAWRKT TSDRGSQTEQ VACPAAVSKA EAAAVLAEEQ
860 870 880 890 900
ARQVQQEKEL ATKEALRKPE VELELKYCEI IAQKVETAVQ NARSRWIQEL
910 920 930 940 950
PMLAEYKALL RAQQQEWAKQ QELAVAHRLS LALSEAKEKW KSELENMKPN
960 970 980 990 1000
VMSVKELEEK VHSLQKELEL KDEEVPVIVR AEVAKARTEW NKEKQEEIHK
1010 1020 1030 1040 1050
IQEQNEEDYR QFLEDHRNKI NEVLAAAKED FVKQKAELLL QKETEFQACL
1060 1070 1080 1090 1100
DQSRKEWTLQ EAQQTQVEIR QYEEDTLTVL AYLLKDTQLE YGGDSQDKQL
1110 1120 1130 1140 1150
LEAMSACSSK WISVQYFEKV KACIQKALHD MLSLLTDSVA SEQEKRKVVK
1160 1170 1180 1190 1200
SSADTVSWTS SEGDSAVPVP LPDSTSVRCA QSSAWLKAEA ETDKKICEIK
1210 1220 1230 1240 1250
GLRCGHCFQE LEKEKQECQD LRRKLEKCRR HLQHLERTHR AAVEKLGEEN
1260 1270 1280 1290 1300
SRVVEELIEE NHDMKNKLEA LRALCRTPPR SLSAGAAESA GPSCSRQALE
1310 1320 1330 1340 1350
ELRGQYIKAV RKIKRDMLRY IQESKERAAE MVKAEVLRER QETARKMRNY
1360 1370 1380 1390 1400
YLSCLQQILQ DNGKEEGAEK KIMSAASKLA TMAELLGTIA ESDCRVRCAQ
1410 1420 1430 1440 1450
AGRSVALPLA SEMLTGTERS ERSGVNHNIP HYVESKPNSG KTLPRSVCEQ
1460 1470 1480 1490 1500
LPGRKAAPRS QRRLEESKHR EMRPMASTAL PSDCRCGDAS CRHSGVLAKD
1510 1520 1530 1540 1550
VAPEFVPCQG EGGFDLHEKR DALGAGSEPL LYSAAHSFLG GAEKNSSPRC
1560 1570 1580 1590 1600
ISESRHTTLR SPSEMPRLKA LMCGSPTETD SIASEKSQGV GSQDSPVKDG
1610 1620 1630 1640 1650
VGPSSSPAWP SDSTLPCGSP AVLFLGDGSQ RTQEMLGDSV QWKQFSATSC
1660 1670 1680 1690 1700
HPDAQKSNMV CRSSHTLDLP KETLHSQQGK MGATLGHPSP QSTDMLKTDF
1710 1720 1730
KRLSGTGPSS LCQKPLIKLT APMPSQQDSG FDSPLE
Length:1,736
Mass (Da):196,534
Last modified:February 5, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i16D6433AFFDEBA14
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32338 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK173060 mRNA Translation: BAD32338.1 Different initiation.
AL928930 Genomic DNA No translation available.
AL929166 Genomic DNA No translation available.
BX321866 Genomic DNA No translation available.
BC026366 mRNA Translation: AAH26366.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS38229.1

NCBI Reference Sequences

More...
RefSeqi
NP_001074560.1, NM_001081091.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.330545

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000089776; ENSMUSP00000087208; ENSMUSG00000068394

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
99100

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:99100

UCSC genome browser

More...
UCSCi
uc008mcs.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173060 mRNA Translation: BAD32338.1 Different initiation.
AL928930 Genomic DNA No translation available.
AL929166 Genomic DNA No translation available.
BX321866 Genomic DNA No translation available.
BC026366 mRNA Translation: AAH26366.1
CCDSiCCDS38229.1
RefSeqiNP_001074560.1, NM_001081091.1
UniGeneiMm.330545

3D structure databases

SMRiA2AUM9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi221186, 81 interactors
ComplexPortaliCPX-1160 CEP152-PLK4 complex
DIPiDIP-56915N
IntActiA2AUM9, 85 interactors
STRINGi10090.ENSMUSP00000087208

PTM databases

iPTMnetiA2AUM9
PhosphoSitePlusiA2AUM9

Proteomic databases

EPDiA2AUM9
MaxQBiA2AUM9
PaxDbiA2AUM9
PeptideAtlasiA2AUM9
PRIDEiA2AUM9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000089776; ENSMUSP00000087208; ENSMUSG00000068394
GeneIDi99100
KEGGimmu:99100
UCSCiuc008mcs.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
22995
MGIiMGI:2139083 Cep152

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiENOG410IGHC Eukaryota
ENOG410XQAW LUCA
GeneTreeiENSGT00940000153127
HOGENOMiHOG000111522
HOVERGENiHBG096403
InParanoidiA2AUM9
KOiK16728
OMAiQSRREWT
OrthoDBi243447at2759
TreeFamiTF332017

Enzyme and pathway databases

ReactomeiR-MMU-2565942 Regulation of PLK1 Activity at G2/M Transition
R-MMU-380259 Loss of Nlp from mitotic centrosomes
R-MMU-380270 Recruitment of mitotic centrosome proteins and complexes
R-MMU-380320 Recruitment of NuMA to mitotic centrosomes
R-MMU-5620912 Anchoring of the basal body to the plasma membrane
R-MMU-8854518 AURKA Activation by TPX2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A2AUM9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000068394 Expressed in 206 organ(s), highest expression level in ventricular system choroidal fissure
GenevisibleiA2AUM9 MM

Family and domain databases

InterProiView protein in InterPro
IPR029598 Cep152
PANTHERiPTHR10337:SF6 PTHR10337:SF6, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCE152_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2AUM9
Secondary accession number(s): Q69ZV8, Q8R0X1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 11, 2013
Last sequence update: February 5, 2008
Last modified: January 16, 2019
This is version 90 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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