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UniProtKB - A2ATY4 (A2ATY4_MOUSE)
Protein
Submitted name:
Zinc finger and BTB domain-containing 34
Gene
Zbtb34
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger and BTB domain-containing 34Imported |
Gene namesi | Name:Zbtb34Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2685195, Zbtb34 |
VEuPathDBi | HostDB:ENSMUSG00000068966 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000068966, Expressed in brain and 256 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | A2ATY4, 1 interactor |
STRINGi | 10090.ENSMUSP00000108783 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 50 – 114 | BTBInterPro annotationAdd BLAST | 65 | |
Domaini | 390 – 417 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 418 – 445 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 446 – 474 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 208 – 227 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 254 – 274 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 307 – 330 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 496 – 518 | DisorderedSequence analysisAdd BLAST | 23 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159944 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | IEISPPY |
OrthoDBi | 1318335at2759 |
TreeFami | TF331184 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
A2ATY4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESTLEECNS RLRFVSGEMD NSSFIQFDVP EHSSTVLSQL NELRLQGKLC
60 70 80 90 100
DIIVHIQGQP FRAHKAVLAA SSPYFRDHSA LSTMSGLSIS VIKNPSVFEQ
110 120 130 140 150
LLSFCYTGRM SLQLKDVVSF LTAASFLQMQ CVIDKCTQIL ESIHSKISVG
160 170 180 190 200
DVDSVTIGAE ENPESRNGVK DGSFFTNPVE ISPPYCPQVR QPPVSSDLRM
210 220 230 240 250
ETTPNKALRS RLQEEGHSDR GSSGSVSEYE IQIEGDHEQG DLLVRESQIT
260 270 280 290 300
EVKVKMEKSD RPSCSDSSSL GDDGYHTEMV DGEQVVAVNV GAYGSVLQHA
310 320 330 340 350
YPYSQTASQP SSVPEAFGGQ TNSSPSRSML SCFRGRGARQ KRALSVHLHS
360 370 380 390 400
DLQGVVQGSD SEAMMNNPGY ESSPRERSAR GYWYPYNERL ICIYCGKSFN
410 420 430 440 450
QKGSLDRHMR LHMGITPFVC KFCGKKYTRK DQLEYHIRGH TDDKPFRCEV
460 470 480 490 500
CGKCFPFQGT LNQHLRKNHP GVTEGRGRME SPERTDMYVE QKLESDASAS
510
EMALDSRLEM HTVSDAPD
Sequence databases
RefSeqi | NP_001078976.1, NM_001085507.1 XP_006498103.1, XM_006498040.3 |
Genome annotation databases
Ensembli | ENSMUST00000091037; ENSMUSP00000088560; ENSMUSG00000068966 ENSMUST00000113158; ENSMUSP00000108783; ENSMUSG00000068966 |
GeneIDi | 241311 |
KEGGi | mmu:241311 |
UCSCi | uc008jhu.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | NP_001078976.1, NM_001085507.1 XP_006498103.1, XM_006498040.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | A2ATY4, 1 interactor |
STRINGi | 10090.ENSMUSP00000108783 |
Proteomic databases
ProteomicsDBi | 331166 |
Protocols and materials databases
Antibodypediai | 7766, 45 antibodies from 13 providers |
Genome annotation databases
Ensembli | ENSMUST00000091037; ENSMUSP00000088560; ENSMUSG00000068966 ENSMUST00000113158; ENSMUSP00000108783; ENSMUSG00000068966 |
GeneIDi | 241311 |
KEGGi | mmu:241311 |
UCSCi | uc008jhu.1, mouse |
Organism-specific databases
CTDi | 403341 |
MGIi | MGI:2685195, Zbtb34 |
VEuPathDBi | HostDB:ENSMUSG00000068966 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159944 |
HOGENOMi | CLU_029118_2_0_1 |
OMAi | IEISPPY |
OrthoDBi | 1318335at2759 |
TreeFami | TF331184 |
Miscellaneous databases
BioGRID-ORCSi | 241311, 3 hits in 65 CRISPR screens |
ChiTaRSi | Zbtb34, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000068966, Expressed in brain and 256 other tissues |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | A2ATY4_MOUSE | |
Accessioni | A2ATY4Primary (citable) accession number: A2ATY4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 20, 2007 |
Last sequence update: | February 20, 2007 | |
Last modified: | January 19, 2022 | |
This is version 129 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |