inaa

Functionⁱ

GO - Molecular functionⁱ

structural molecule activity Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Internexin neuronal intermediate filament protein, alpha aImported
Gene namesⁱ	Name:inaaImported
Organismⁱ	Danio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifierⁱ	7955 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Otomorpha › Ostariophysi › Otophysi › Cypriniphysae › Cypriniformes › Cyprinoidea › Cyprinidae › Danio
Proteomesⁱ	UP000000437 Componentⁱ: Chromosome 13

Organism-specific databases

ZFINⁱ	ZDB-GENE-060531-65 inaa

ZFINⁱ

ZDB-GENE-060531-65 inaa

Subcellular locationⁱ

GO - Cellular component

Keywords - Cellular componentⁱ

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	A2ATX5
PeptideAtlas More...PeptideAtlasⁱ	A2ATX5
PRIDEⁱ	A2ATX5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSDARG00000011862 Expressed in 21 organ(s), highest expression level in retina

Bgeeⁱ

ENSDARG00000011862 Expressed in 21 organ(s), highest expression level in retina

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	7955.ENSDARP00000012437

STRINGⁱ

7955.ENSDARP00000012437

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A2ATX5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	94 – 404	IF rodInterPro annotationAdd BLAST		311

Coiled coil

Feature key	Position(s)	DescriptionActions	Length
Coiled coilⁱ	112 – 132	Sequence analysisAdd BLAST	21
Coiled coilⁱ	140 – 230	Sequence analysisAdd BLAST	91
Coiled coilⁱ	288 – 346	Sequence analysisAdd BLAST	59
Coiled coilⁱ	355 – 382	Sequence analysisAdd BLAST	28

Sequence similaritiesⁱ

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domainⁱ

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG410IGME Eukaryota ENOG410XPTM LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000143989
HOGENOMⁱ	HOG000230977
HOVERGENⁱ	HBG013015
InParanoidⁱ	A2ATX5
KEGG Orthology (KO) More...KOⁱ	K07608
OMAⁱ	NEAMRAT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G12MK
PhylomeDBⁱ	A2ATX5
TreeFamⁱ	TF330122

Family and domain databases

InterProⁱ	View protein in InterPro IPR001664 IF IPR018039 IF_conserved IPR039008 IF_rod_dom IPR006821 Intermed_filament_DNA-bd
PANTHERⁱ	PTHR23239 PTHR23239, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00038 Filament, 1 hit PF04732 Filament_head, 1 hit
SMARTⁱ	View protein in SMART SM01391 Filament, 1 hit
PROSITEⁱ	View protein in PROSITE PS00226 IF_ROD_1, 1 hit PS51842 IF_ROD_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A2ATX5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSYGSDHYMS SSYRKLFGDN PRFAGSRMSN VSPRSSMSSS GFRSQSVSRS 
        60         70         80         90        100
SASPAGYYKR SGRSSSFSPV HFDSVDFSQT SVLNNEFKIV RTNEKEQLQG 
       110        120        130        140        150
LNDRFAMFIE KVRNLEQHNK VLETELVSLR QRQNEPSRLA ELYQQEIRDL 
       160        170        180        190        200
RAQVDELNNE KSHILIERDS IEEDLQKLRG KFEEEIRARE EAEQTLRSYK 
       210        220        230        240        250
KDVDDATMVR VDLERKVESL LDEINFLRKV HDEEVTELTN MIQAAQISVE 
       260        270        280        290        300
VELSKPDLTS ALKDIRGQYE TLASKNLQSA EEWYKSKFAS LNEQATRTNE 
       310        320        330        340        350
AMRATREEVN DYRRQLQSKT IEIETLRGTN ESLERQIREM EEAHNAEVAG 
       360        370        380        390        400
YQETIGQLDL ELRNTKSEMA RHLREYQDLL NVKMALDIEI AAYRKLLEGE 
       410        420        430        440        450
ETHFSSGVTF SSTPSITYGY QSRSAFTSTR NPKKEREEEG HPKSKTAAKR 
       460        470 
EENTDENVGI KKTEKNDAVD VNSN

Length:474

Mass (Da):54,641

Last modified:February 20, 2007 - v1

Checksum:ⁱBE1574EE1AAF3FE5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL928951 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001138256.1, NM_001144784.1
UniGeneⁱ	Dr.82634

Genome annotation databases

Ensemblⁱ	ENSDART00000027213; ENSDARP00000012437; ENSDARG00000011862
GeneIDⁱ	555251
KEGGⁱ	dre:555251

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
A2ATX5	Alpha-internexin		HUMAN		499	UniRef50_Q16352
Alpha-internexin		RAT		505
Alpha-internexin		MOUSE		501
Alpha-internexin		BOVIN		499
Low molecular weight neuronal intermediate filament		XENLA		470
+208

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL928951 Genomic DNA No translation available.
RefSeqⁱ	NP_001138256.1, NM_001144784.1
UniGeneⁱ	Dr.82634

3D structure databases

ProteinModelPortalⁱ	A2ATX5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	7955.ENSDARP00000012437

STRINGⁱ

7955.ENSDARP00000012437

Proteomic databases

PaxDbⁱ	A2ATX5
PeptideAtlasⁱ	A2ATX5
PRIDEⁱ	A2ATX5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSDART00000027213; ENSDARP00000012437; ENSDARG00000011862
GeneIDⁱ	555251
KEGGⁱ	dre:555251

Organism-specific databases

CTDⁱ	555251
ZFINⁱ	ZDB-GENE-060531-65 inaa

Phylogenomic databases

eggNOGⁱ	ENOG410IGME Eukaryota ENOG410XPTM LUCA
GeneTreeⁱ	ENSGT00910000143989
HOGENOMⁱ	HOG000230977
HOVERGENⁱ	HBG013015
InParanoidⁱ	A2ATX5
KOⁱ	K07608
OMAⁱ	NEAMRAT
OrthoDBⁱ	EOG091G12MK
PhylomeDBⁱ	A2ATX5
TreeFamⁱ	TF330122

Gene expression databases

Bgeeⁱ	ENSDARG00000011862 Expressed in 21 organ(s), highest expression level in retina

Bgeeⁱ

ENSDARG00000011862 Expressed in 21 organ(s), highest expression level in retina

Family and domain databases

InterProⁱ	View protein in InterPro IPR001664 IF IPR018039 IF_conserved IPR039008 IF_rod_dom IPR006821 Intermed_filament_DNA-bd
PANTHERⁱ	PTHR23239 PTHR23239, 1 hit
Pfamⁱ	View protein in Pfam PF00038 Filament, 1 hit PF04732 Filament_head, 1 hit
SMARTⁱ	View protein in SMART SM01391 Filament, 1 hit
PROSITEⁱ	View protein in PROSITE PS00226 IF_ROD_1, 1 hit PS51842 IF_ROD_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A2ATX5_DANRE
Accessionⁱ	A2ATX5Primary (citable) accession number: A2ATX5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 20, 2007
	Last sequence update:	February 20, 2007
	Last modified:	September 12, 2018
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2ATX5 (A2ATX5_DANRE)

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Internexin neuronal intermediate filament protein, alpha a

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ