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Protein

Transmembrane protein 236

Gene

Tmem236

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 236
Gene namesi
Name:Tmem236
Synonyms:Fam23a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1919309 Tmem236

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei47 – 67HelicalSequence analysisAdd BLAST21
Transmembranei86 – 106HelicalSequence analysisAdd BLAST21
Transmembranei122 – 142HelicalSequence analysisAdd BLAST21
Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004095381 – 344Transmembrane protein 236Add BLAST344

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi114N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA2ARJ3
PeptideAtlasiA2ARJ3
PRIDEiA2ARJ3

PTM databases

PhosphoSitePlusiA2ARJ3

Expressioni

Gene expression databases

BgeeiENSMUSG00000061531 Expressed in 38 organ(s), highest expression level in intestine
GenevisibleiA2ARJ3 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000076722

Structurei

3D structure databases

ProteinModelPortaliA2ARJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM236 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGEQ Eukaryota
ENOG410YD0S LUCA
GeneTreeiENSGT00390000015525
HOGENOMiHOG000231830
HOVERGENiHBG080454
InParanoidiA2ARJ3
OMAiWLYPVYI
OrthoDBiEOG091G0DFD
PhylomeDBiA2ARJ3
TreeFamiTF328759

Family and domain databases

InterProiView protein in InterPro
IPR020394 Uncharacterised_FAM23-like_TM
PANTHERiPTHR31453 PTHR31453, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD098445 Uncharacterised_FAM23-like_TM, 1 hit

Sequencei

Sequence statusi: Complete.

A2ARJ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGKIIKLV VFELLEFAAF SIPTLVIMEQ FATANQRTKS ERTHYWLIVS
60 70 80 90 100
CSIAYVAVVS LLIWVPVKVV LYKKRHLYKK IIGWRPVLVM CVVLTTLPSF
110 120 130 140 150
SFSIAVTEVQ KNINGSANSL PESLPDLPVS LVLLSLIVVD IIEKLRQYPL
160 170 180 190 200
RGSQKGYEDN DICITSLQQI KTVTEQVVQS DGNPASAQAA KPTAMSQPRN
210 220 230 240 250
HVAVLAGPLE PSFQSRILRT MSQRDVRAEL FLRSFLMWAD TVEMLRVAGH
260 270 280 290 300
QAVYKSAWLY PVYIFSFISL LRMVFTPKNP LLNSLGILMQ DLPFVFLRLS
310 320 330 340
LILALGTITP VLGLCKNVLV TISYIYFNYV TKLRPFSAFE TSPF
Length:344
Mass (Da):38,680
Last modified:February 20, 2007 - v1
Checksum:i240DE545809D179E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845434 Genomic DNA No translation available.
CCDSiCCDS38049.1
RefSeqiNP_001074779.1, NM_001081310.2
UniGeneiMm.158781

Genome annotation databases

EnsembliENSMUST00000077517; ENSMUSP00000076722; ENSMUSG00000061531
GeneIDi625286
KEGGimmu:625286
UCSCiuc008ikj.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845434 Genomic DNA No translation available.
CCDSiCCDS38049.1
RefSeqiNP_001074779.1, NM_001081310.2
UniGeneiMm.158781

3D structure databases

ProteinModelPortaliA2ARJ3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000076722

PTM databases

PhosphoSitePlusiA2ARJ3

Proteomic databases

PaxDbiA2ARJ3
PeptideAtlasiA2ARJ3
PRIDEiA2ARJ3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000077517; ENSMUSP00000076722; ENSMUSG00000061531
GeneIDi625286
KEGGimmu:625286
UCSCiuc008ikj.1 mouse

Organism-specific databases

CTDi653567
MGIiMGI:1919309 Tmem236

Phylogenomic databases

eggNOGiENOG410IGEQ Eukaryota
ENOG410YD0S LUCA
GeneTreeiENSGT00390000015525
HOGENOMiHOG000231830
HOVERGENiHBG080454
InParanoidiA2ARJ3
OMAiWLYPVYI
OrthoDBiEOG091G0DFD
PhylomeDBiA2ARJ3
TreeFamiTF328759

Miscellaneous databases

PROiPR:A2ARJ3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000061531 Expressed in 38 organ(s), highest expression level in intestine
GenevisibleiA2ARJ3 MM

Family and domain databases

InterProiView protein in InterPro
IPR020394 Uncharacterised_FAM23-like_TM
PANTHERiPTHR31453 PTHR31453, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD098445 Uncharacterised_FAM23-like_TM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTM236_MOUSE
AccessioniPrimary (citable) accession number: A2ARJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: February 20, 2007
Last modified: September 12, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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