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Protein

Glycerol-3-phosphate dehydrogenase

Gene

Gpd2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi690 – 701PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCalciumPROSITE-ProRule annotation, FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:Gpd2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:99778 Gpd2

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiA2AQR0
PeptideAtlasiA2AQR0
PRIDEiA2AQR0

PTM databases

SwissPalmiA2AQR0

Expressioni

Gene expression databases

BgeeiENSMUSG00000026827
ExpressionAtlasiA2AQR0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA2AQR0
SMRiA2AQR0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini641 – 676EF-handInterPro annotationAdd BLAST36
Domaini677 – 712EF-handInterPro annotationAdd BLAST36

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0042 Eukaryota
COG0578 LUCA
GeneTreeiENSGT00390000001718
HOGENOMiHOG000004813
HOVERGENiHBG005897
OMAiVPYYWVG
OrthoDBiEOG091G03ER
PhylomeDBiA2AQR0
TreeFamiTF300359

Family and domain databases

CDDicd00051 EFh, 1 hit
Gene3Di1.10.8.870, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR031656 DAO_C
IPR038299 DAO_C_sf
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR006076 FAD-dep_OxRdtase
IPR036188 FAD/NAD-bd_sf
IPR000447 G3P_DH_FAD-dep
PANTHERiPTHR11985 PTHR11985, 1 hit
PfamiView protein in Pfam
PF01266 DAO, 1 hit
PF16901 DAO_C, 1 hit
PF13499 EF-hand_7, 1 hit
PRINTSiPR01001 FADG3PDH
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SUPFAMiSSF47473 SSF47473, 1 hit
SSF51905 SSF51905, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS00977 FAD_G3PDH_1, 1 hit
PS00978 FAD_G3PDH_2, 1 hit

Sequencei

Sequence statusi: Complete.

A2AQR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFQKAVKGT ILVGGGALAT VLGLSPFAHY RRKQVSLAYV EAAGYLTEPV
60 70 80 90 100
NREPPSREAQ LMTLKNTPEF DILVIGGGAT GCGCALDAVT RGLKTALVER
110 120 130 140 150
DDFSSGTSSR STKLIHGGVR YLQKAIMNLD VEQYRMVKEA LHERANLLEI
160 170 180 190 200
APHLSAPLPI MLPLYKWWQL PYYWVGIKMY DLVAGSQCLK SSYVLSKSRA
210 220 230 240 250
LEHFPMLQKD KLVGAIVYYD GQHNDARMNL AIALTAARYG AATANYMEVV
260 270 280 290 300
SLLKKTDPET GKERVSGARC KDVLTGQEFD VRAKCVINAS GPFTDSVRKM
310 320 330 340 350
DDKNVVPICQ PSAGVHIVMP GYYSPENMGL LDPATSDGRV IFFLPWEKMT
360 370 380 390 400
IAGTTDTPTD VTHHPIPSEE DINFILNEVR NYLSSDVEVR RGDVLAAWSG
410 420 430 440 450
IRPLVTDPKS ADTQSISRNH VVDISDSGLI TIAGGKWTTY RSMAEDTVDA
460 470 480 490 500
AVKFHNLNAG PSRTVGLFLQ GGKDWSPTLY IRLVQDYGLE SEVAQHLAKT
510 520 530 540 550
YGDKAFEVAK MASVTGKRWP VVGVRLVSEF PYIEAEVKYG IKEYACTAVD
560 570 580 590 600
MISRRTRLAF LNVQAAEEAL PRIVELMGRE LNWSELRKQC VTYDSDGSTV
610 620 630 640 650
ATSWSSQEEL ETATRFLYYE MGYKSRTEQL TDSTEISLLP SDIDRYKKRF
660 670 680 690 700
HKFDEDEKGF ITIVDVQRVL ESINVQMDEN TLHEILCEVD LNKNGQVELH
710 720 730 740
EFLQLMSAVQ KGRVSGSRLA ILMKTAEENL DRRVPIPVDR SCGGL
Length:745
Mass (Da):82,830
Last modified:February 20, 2007 - v1
Checksum:iCCFCDECCCE414876
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844871 Genomic DNA No translation available.
AL845166 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000112618; ENSMUSP00000108237; ENSMUSG00000026827

Similar proteinsi

Entry informationi

Entry nameiA2AQR0_MOUSE
AccessioniPrimary (citable) accession number: A2AQR0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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