UniProtKB - A2AKB9 (DCA10_MOUSE)

BLAST

>sp|A2AKB9|DCA10_MOUSE DDB1- and CUL4-associated factor 10 OS=Mus musculus OX=10090 GN=Dcaf10 PE=1 SV=1
MFPFGPHSPGGDETAGAEEPPPLGGPAAASRPPSPAPRPASPQRGADAASPPPVAGSPRL
PGGPAVSPAERAGEFAAPGALELSAATASASQAKLSPSSSPRRRSRPDWRAGGRSRQGLG
AGLGGPGARLFGWLRERSLGRGLFVDPARDNFRTMTNLYGSIHPADSVYLSTRTHGAVFN
LEYSPDGSVLTVACEQTEVLLFDPISSKHIKTLSEAHEDCVNNIRFLDNRLFATCSDDTT
IALWDLRKLNTKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRCTEDGCPHK
KFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHELDLTKSLEVGSYPILRARRTTSSSDL
TTTSSSSGSRVSGSPCHHNDSNSTEKHMSRASQREGVSPRNSLEVLTPEVPGERDRGNCI
TSLQLHPKGWATLLRCSSNTDDQEWTCVYEFQEGAPVRPVSPRCSLRLTHYIEEANVGRG
YIKELCFSPDGRMISSPHGYGIRLLGFDKQCSELVDCLPKEASPLRVIRSLYSHNDVVLT
TKFSPTHCQIASGCLSGRVSLYQPKF

Align

Format
Add to basket Added to basket
History
Entry version 94 (07 Nov 2018)
Sequence version 1 (20 Feb 2007)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

DDB1- and CUL4-associated factor 10

Gene

Dcaf10

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.By similarity

Pathwayⁱ: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processⁱ

protein ubiquitination Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ubl conjugation pathway

Biological process

Ubl conjugation pathway

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8951664 Neddylation
UniPathwayⁱ	UPA00143

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: DDB1- and CUL4-associated factor 10 Alternative name(s): WD repeat-containing protein 32
Gene namesⁱ	Name:Dcaf10 Synonyms:Wdr32
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 4

Organism-specific databases

MGIⁱ	MGI:2140179 Dcaf10

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000306834	1 – 566	DDB1- and CUL4-associated factor 10Add BLAST		566

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	50	PhosphoserineCombined sources	1
Modified residueⁱ	57	PhosphoserineCombined sources	1
Modified residueⁱ	67	PhosphoserineBy similarity	1
Modified residueⁱ	96	PhosphoserineCombined sources	1
Modified residueⁱ	99	PhosphoserineBy similarity	1
Modified residueⁱ	100	PhosphoserineCombined sources	1
Modified residueⁱ	141	Omega-N-methylarginineCombined sources	1
Modified residueⁱ	356	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Methylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	A2AKB9
PaxDbⁱ	A2AKB9
PeptideAtlas More...PeptideAtlasⁱ	A2AKB9
PRIDEⁱ	A2AKB9

PTM databases

iPTMnetⁱ	A2AKB9
PhosphoSitePlusⁱ	A2AKB9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000035572 Expressed in 238 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_WDR32
ExpressionAtlasⁱ	A2AKB9 baseline and differential
Genevisibleⁱ	A2AKB9 MM

Interactionⁱ

Subunit structureⁱ

Interacts with DDB1.By similarity

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000117082

STRINGⁱ

10090.ENSMUSP00000117082

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A2AKB9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	173 – 212	WD 1Add BLAST	40
Repeatⁱ	216 – 254	WD 2Add BLAST	39
Repeatⁱ	258 – 297	WD 3Add BLAST	40
Repeatⁱ	303 – 342	WD 4Add BLAST	40
Repeatⁱ	415 – 455	WD 5Add BLAST	41
Repeatⁱ	477 – 515	WD 6Add BLAST	39
Repeatⁱ	533 – 566	WD 7Add BLAST	34

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	3 – 68	Pro-richAdd BLAST		66

Sequence similaritiesⁱ

Belongs to the WD repeat DCAF10 family.Curated

Keywords - Domainⁱ

Repeat, WD repeat

Phylogenomic databases

eggNOGⁱ	KOG4155 Eukaryota ENOG410XP1Z LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012666
HOVERGENⁱ	HBG055755
InParanoidⁱ	A2AKB9
KEGG Orthology (KO) More...KOⁱ	K11802
OMAⁱ	SEWTCIH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G09PD
PhylomeDBⁱ	A2AKB9
TreeFamⁱ	TF323434

Family and domain databases

Gene3Dⁱ	2.130.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR039085 DCA10 IPR000772 Ricin_B_lectin IPR015943 WD40/YVTN_repeat-like_dom_sf IPR001680 WD40_repeat IPR019775 WD40_repeat_CS IPR017986 WD40_repeat_dom IPR036322 WD40_repeat_dom_sf
PANTHERⁱ	PTHR14588 PTHR14588, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00400 WD40, 2 hits
SMARTⁱ	View protein in SMART SM00320 WD40, 5 hits
SUPFAMⁱ	SSF50978 SSF50978, 1 hit
PROSITEⁱ	View protein in PROSITE PS00678 WD_REPEATS_1, 1 hit PS50082 WD_REPEATS_2, 2 hits PS50294 WD_REPEATS_REGION, 1 hit

Sequences (4+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 4 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show all Align All

Isoform 1 (identifier: A2AKB9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFPFGPHSPG GDETAGAEEP PPLGGPAAAS RPPSPAPRPA SPQRGADAAS 
        60         70         80         90        100
PPPVAGSPRL PGGPAVSPAE RAGEFAAPGA LELSAATASA SQAKLSPSSS 
       110        120        130        140        150
PRRRSRPDWR AGGRSRQGLG AGLGGPGARL FGWLRERSLG RGLFVDPARD 
       160        170        180        190        200
NFRTMTNLYG SIHPADSVYL STRTHGAVFN LEYSPDGSVL TVACEQTEVL 
       210        220        230        240        250
LFDPISSKHI KTLSEAHEDC VNNIRFLDNR LFATCSDDTT IALWDLRKLN 
       260        270        280        290        300
TKVCTLHGHT SWVKNIEYDT NTRLLVTSGF DGNVIIWDTN RCTEDGCPHK 
       310        320        330        340        350
KFFHTRFLMR MRLTPDCSKM LISTSSGYLL ILHELDLTKS LEVGSYPILR 
       360        370        380        390        400
ARRTTSSSDL TTTSSSSGSR VSGSPCHHND SNSTEKHMSR ASQREGVSPR 
       410        420        430        440        450
NSLEVLTPEV PGERDRGNCI TSLQLHPKGW ATLLRCSSNT DDQEWTCVYE 
       460        470        480        490        500
FQEGAPVRPV SPRCSLRLTH YIEEANVGRG YIKELCFSPD GRMISSPHGY 
       510        520        530        540        550
GIRLLGFDKQ CSELVDCLPK EASPLRVIRS LYSHNDVVLT TKFSPTHCQI 
       560 
ASGCLSGRVS LYQPKF

Length:566

Mass (Da):61,558

Last modified:February 20, 2007 - v1

Checksum:ⁱ4923778CDA90E6F8

Isoform 2 (identifier: A2AKB9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
359-395: Missing.

« Hide

        10         20         30         40         50
MFPFGPHSPG GDETAGAEEP PPLGGPAAAS RPPSPAPRPA SPQRGADAAS 
        60         70         80         90        100
PPPVAGSPRL PGGPAVSPAE RAGEFAAPGA LELSAATASA SQAKLSPSSS 
       110        120        130        140        150
PRRRSRPDWR AGGRSRQGLG AGLGGPGARL FGWLRERSLG RGLFVDPARD 
       160        170        180        190        200
NFRTMTNLYG SIHPADSVYL STRTHGAVFN LEYSPDGSVL TVACEQTEVL 
       210        220        230        240        250
LFDPISSKHI KTLSEAHEDC VNNIRFLDNR LFATCSDDTT IALWDLRKLN 
       260        270        280        290        300
TKVCTLHGHT SWVKNIEYDT NTRLLVTSGF DGNVIIWDTN RCTEDGCPHK 
       310        320        330        340        350
KFFHTRFLMR MRLTPDCSKM LISTSSGYLL ILHELDLTKS LEVGSYPILR 
       360        370        380        390        400
ARRTTSSSGV SPRNSLEVLT PEVPGERDRG NCITSLQLHP KGWATLLRCS 
       410        420        430        440        450
SNTDDQEWTC VYEFQEGAPV RPVSPRCSLR LTHYIEEANV GRGYIKELCF 
       460        470        480        490        500
SPDGRMISSP HGYGIRLLGF DKQCSELVDC LPKEASPLRV IRSLYSHNDV 
       510        520 
VLTTKFSPTH CQIASGCLSG RVSLYQPKF

Show »

Length:529

Mass (Da):57,614

Checksum:ⁱ6DFDC654E4D001EC

Isoform 3 (identifier: A2AKB9-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-308: Missing.

« Hide

        10         20         30         40         50
MRMRLTPDCS KMLISTSSGY LLILHELDLT KSLEVGSYPI LRARRTTSSS 
        60         70         80         90        100
DLTTTSSSSG SRVSGSPCHH NDSNSTEKHM SRASQREGVS PRNSLEVLTP 
       110        120        130        140        150
EVPGERDRGN CITSLQLHPK GWATLLRCSS NTDDQEWTCV YEFQEGAPVR 
       160        170        180        190        200
PVSPRCSLRL THYIEEANVG RGYIKELCFS PDGRMISSPH GYGIRLLGFD 
       210        220        230        240        250
KQCSELVDCL PKEASPLRVI RSLYSHNDVV LTTKFSPTHC QIASGCLSGR 

VSLYQPKF

Note: No experimental confirmation available.

Show »

Length:258

Mass (Da):28,626

Checksum:ⁱ5901B43E00473C8B

Isoform 4 (identifier: A2AKB9-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
226-566: Missing.

« Hide

        10         20         30         40         50
MFPFGPHSPG GDETAGAEEP PPLGGPAAAS RPPSPAPRPA SPQRGADAAS 
        60         70         80         90        100
PPPVAGSPRL PGGPAVSPAE RAGEFAAPGA LELSAATASA SQAKLSPSSS 
       110        120        130        140        150
PRRRSRPDWR AGGRSRQGLG AGLGGPGARL FGWLRERSLG RGLFVDPARD 
       160        170        180        190        200
NFRTMTNLYG SIHPADSVYL STRTHGAVFN LEYSPDGSVL TVACEQTEVL 
       210        220 
LFDPISSKHI KTLSEAHEDC VNNIR

Note: No experimental confirmation available.

Show »

Length:225

Mass (Da):23,289

Checksum:ⁱ028BF807BA1FE6EB

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	Z4YN28	Z4YN28_MOUSE		DDB1- and CUL4-associated factor 10 DDB1- and CUL4-associated factor 10	Dcaf10	225	Annotation score:

Sequence cautionⁱ

The sequence AAH27317 differs from that shown. Reason: Erroneous initiation.Curated

The sequence AAH85101 differs from that shown. Reason: Erroneous initiation.Curated

The sequence BAC38912 differs from that shown. Reason: Erroneous initiation.Curated

The sequence CAM20443 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	202	F → L in BAE38101 (PubMed:16141072).Curated	1
Sequence conflictⁱ	235	C → S in AAH27317 (PubMed:15489334).Curated	1
Sequence conflictⁱ	323	S → P in BAC38912 (PubMed:16141072).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_028514	1 – 308	Missing in isoform 3. 1 PublicationAdd BLAST	308
Alternative sequenceⁱVSP_028515	226 – 566	Missing in isoform 4. 1 PublicationAdd BLAST	341
Alternative sequenceⁱVSP_028516	359 – 395	Missing in isoform 2. CuratedAdd BLAST	37

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK045241 mRNA Translation: BAC32276.1 AK076417 mRNA Translation: BAC36330.1 AK083428 mRNA Translation: BAC38912.1 Different initiation. AK165246 mRNA Translation: BAE38101.1 AL772376, AL772285 Genomic DNA Translation: CAM20447.1 AL772285, AL772376 Genomic DNA Translation: CAM26867.1 AL772376 Genomic DNA Translation: CAM20443.1 Sequence problems. BC027317 mRNA Translation: AAH27317.1 Different initiation. BC085101 mRNA Translation: AAH85101.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS38754.1 [A2AKB9-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_694807.2, NM_153167.2 [A2AKB9-1]
UniGeneⁱ	Mm.317668

Genome annotation databases

Ensemblⁱ	ENSMUST00000155551; ENSMUSP00000117082; ENSMUSG00000035572 [A2AKB9-1]
GeneIDⁱ	242418
KEGGⁱ	mmu:242418
UCSC genome browser More...UCSCⁱ	uc008ssm.1 mouse [A2AKB9-4] uc008ssn.1 mouse [A2AKB9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Protein	Similar proteins		Species	Score	Length	Source
A2AKB9	Isoform 4 of DDB1- and CUL4-associated factor 10		MOUSE		225	UniRef100_A2AKB9
Isoform 3 of DDB1- and CUL4-associated factor 10		MOUSE		258
A2AKB9-2	DDB1- and CUL4-associated factor 10 (Fragment)		MOUSE		225	UniRef100_A2AKB9-2

Protein	Similar proteins		Species	Score	Length	Source
A2AKB9	Isoform 4 of DDB1- and CUL4-associated factor 10		MOUSE		225	UniRef90_A2AKB9
DDB1 and CUL4-associated factor 10		RAT		563
Uncharacterized protein		CAVPO		556
DDB1- and CUL4-associated factor 10		DIPOR		554
WD repeat-containing protein 32		HETGA		413
+10
A2AKB9-2	DDB1- and CUL4-associated factor 10 (Fragment)		MOUSE		225	UniRef90_A2AKB9-2

Protein	Similar proteins		Species	Score	Length	Source
A2AKB9	DDB1- and CUL4-associated factor 10		HUMAN		559	UniRef50_Q5QP82
DDB1- and CUL4-associated factor 10		DANRE		508
WD repeat-containing protein 32 (Fragment)		MACMU		379
WD repeat-containing protein 32 (Fragment)		MACFA		342
Uncharacterized protein		MANLE		341
+271

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK045241 mRNA Translation: BAC32276.1 AK076417 mRNA Translation: BAC36330.1 AK083428 mRNA Translation: BAC38912.1 Different initiation. AK165246 mRNA Translation: BAE38101.1 AL772376, AL772285 Genomic DNA Translation: CAM20447.1 AL772285, AL772376 Genomic DNA Translation: CAM26867.1 AL772376 Genomic DNA Translation: CAM20443.1 Sequence problems. BC027317 mRNA Translation: AAH27317.1 Different initiation. BC085101 mRNA Translation: AAH85101.1 Different initiation.
CCDSⁱ	CCDS38754.1 [A2AKB9-1]
RefSeqⁱ	NP_694807.2, NM_153167.2 [A2AKB9-1]
UniGeneⁱ	Mm.317668

3D structure databases

ProteinModelPortalⁱ	A2AKB9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000117082

STRINGⁱ

10090.ENSMUSP00000117082

PTM databases

iPTMnetⁱ	A2AKB9
PhosphoSitePlusⁱ	A2AKB9

Proteomic databases

MaxQBⁱ	A2AKB9
PaxDbⁱ	A2AKB9
PeptideAtlasⁱ	A2AKB9
PRIDEⁱ	A2AKB9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000155551; ENSMUSP00000117082; ENSMUSG00000035572 [A2AKB9-1]
GeneIDⁱ	242418
KEGGⁱ	mmu:242418
UCSCⁱ	uc008ssm.1 mouse [A2AKB9-4] uc008ssn.1 mouse [A2AKB9-1]

Organism-specific databases

CTDⁱ	79269
MGIⁱ	MGI:2140179 Dcaf10

Phylogenomic databases

eggNOGⁱ	KOG4155 Eukaryota ENOG410XP1Z LUCA
GeneTreeⁱ	ENSGT00390000012666
HOVERGENⁱ	HBG055755
InParanoidⁱ	A2AKB9
KOⁱ	K11802
OMAⁱ	SEWTCIH
OrthoDBⁱ	EOG091G09PD
PhylomeDBⁱ	A2AKB9
TreeFamⁱ	TF323434

Enzyme and pathway databases

UniPathwayⁱ	UPA00143
Reactomeⁱ	R-MMU-8951664 Neddylation

Miscellaneous databases

ChiTaRSⁱ	Dcaf10 mouse
Protein Ontology More...PROⁱ	PR:A2AKB9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000035572 Expressed in 238 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_WDR32
ExpressionAtlasⁱ	A2AKB9 baseline and differential
Genevisibleⁱ	A2AKB9 MM

Family and domain databases

Gene3Dⁱ	2.130.10.10, 2 hits
InterProⁱ	View protein in InterPro IPR039085 DCA10 IPR000772 Ricin_B_lectin IPR015943 WD40/YVTN_repeat-like_dom_sf IPR001680 WD40_repeat IPR019775 WD40_repeat_CS IPR017986 WD40_repeat_dom IPR036322 WD40_repeat_dom_sf
PANTHERⁱ	PTHR14588 PTHR14588, 1 hit
Pfamⁱ	View protein in Pfam PF00400 WD40, 2 hits
SMARTⁱ	View protein in SMART SM00320 WD40, 5 hits
SUPFAMⁱ	SSF50978 SSF50978, 1 hit
PROSITEⁱ	View protein in PROSITE PS00678 WD_REPEATS_1, 1 hit PS50082 WD_REPEATS_2, 2 hits PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DCA10_MOUSE
Accessionⁱ	A2AKB9Primary (citable) accession number: A2AKB9 Secondary accession number(s): A2AKV8 Q8K3A5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
	Last sequence update:	February 20, 2007
	Last modified:	November 7, 2018
	This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PATHWAY comments
Index of metabolic and biosynthesis pathways

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2AKB9 (DCA10_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

DDB1- and CUL4-associated factor 10

Dcaf10

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

Pathwayⁱ: protein ubiquitination

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ