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Entry version 99 (07 Apr 2021)
Sequence version 1 (20 Feb 2007)
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Protein

BCLAF1 and THRAP3 family member 3

Gene

BCLAF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A2AJT9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BCLAF1 and THRAP3 family member 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BCLAF3Imported
Synonyms:CXorf23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:27413, BCLAF3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A2AJT9

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000173681.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000173681

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134885371

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A2AJT9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BCLAF3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002874341 – 711BCLAF1 and THRAP3 family member 3Add BLAST711

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei15PhosphoserineCombined sources1
Modified residuei17PhosphoserineCombined sources1
Modified residuei78PhosphoserineCombined sources1
Modified residuei80PhosphoserineCombined sources1
Modified residuei187PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki400Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei402PhosphoserineCombined sources1
Modified residuei578PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A2AJT9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A2AJT9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A2AJT9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2AJT9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A2AJT9

PeptideAtlas

More...
PeptideAtlasi
A2AJT9

PRoteomics IDEntifications database

More...
PRIDEi
A2AJT9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
405 [A2AJT9-1]
406 [A2AJT9-2]
407 [A2AJT9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2AJT9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A2AJT9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173681, Expressed in secondary oocyte and 167 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2AJT9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2AJT9, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000173681, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
129173, 3 interactors

Protein interaction database and analysis system

More...
IntActi
A2AJT9, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000369009

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A2AJT9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2AJT9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BCLAF1/THRAP3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S4TN, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183163

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_024256_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2AJT9

Identification of Orthologs from Complete Genome Data

More...
OMAi
RESDCFN

Database of Orthologous Groups

More...
OrthoDBi
442192at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2AJT9

TreeFam database of animal gene trees

More...
TreeFami
TF335939

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029199, THRAP3_BCLAF1

The PANTHER Classification System

More...
PANTHERi
PTHR15268, PTHR15268, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15440, THRAP3_BCLAF1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A2AJT9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MARSRSRSPR WKHRSLSPVP RNAEHYKQRH SHGHYGCEYR KDPKRPVAWR
60 70 80 90 100
MDSEKHGQSK PRIPSRGNIY YQSYEHRSPS PNIRNSLENV YMYKPHRGYS
110 120 130 140 150
PGRGDSNRRA QYMPKYSEGI PYKEHERNSY PQKVQGGHSP DDHRVRGSGK
160 170 180 190 200
GGKPPQRSIA DSFRFEGKWH EDELRHQRIQ EEKYSQSTRR GSEDFETRSS
210 220 230 240 250
FQKRYPEDRD FRKYGHTSKR PKDVERYESR EPARNPKWKP EHSLPPYQED
260 270 280 290 300
TDQWNLGPQT YRHAEREHPE TSSATKVSYD YRHKRPKLLD GDQDFSDGRT
310 320 330 340 350
QKYCKEEDRK YSFQKGPLNR ELDCFNTGRG RETQDGQVKE PFKPSKKDSI
360 370 380 390 400
ACTYSNKNDV DLRSSNDKWK EKIKKEGDCR KESNSSSNQL DKSQKLPDVK
410 420 430 440 450
PSPINLRKKS LTVKVDVKKT VDTFRVASSY STERQMSHDL VAVGRKSENF
460 470 480 490 500
HPVFEHLDST QNTENKPTGE FAQEIITIIH QVKANYFPSP GITLHERFST
510 520 530 540 550
MQDIHKADVN EIPLNSDPEI HRRIDMSLAE LQSKQAVIYE SEQTLIKIID
560 570 580 590 600
PNDLRHDIER RRKERLQNED EHIFHIASAA ERDDQNSSFS KVKNVHTDGF
610 620 630 640 650
QKPTHFIKSN FRKCIEKPYM NYTTQRKDII THKPFEVEGN HRNTRVRPFK
660 670 680 690 700
SNFRGGRCQP NYKSGLVQKS LYIQAKYQRL RFTGPRGFIT HKFRERLMRK
710
KKEYTDVATG I
Length:711
Mass (Da):83,871
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED389DC27B6C2D1B
GO
Isoform 2 (identifier: A2AJT9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     592-620: Missing.

Show »
Length:682
Mass (Da):80,395
Checksum:iC1373DE270D5966D
GO
Isoform 3 (identifier: A2AJT9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     592-711: VKNVHTDGFQ...KEYTDVATGI → GLALSPRLECGVTITAYCSLYLQDSSYLPPQPPE

Show »
Length:625
Mass (Da):73,187
Checksum:i435AB65759C38A26
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z385F2Z385_HUMAN
BCLAF1 and THRAP3 family member 3
BCLAF3
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BXX2H7BXX2_HUMAN
BCLAF1 and THRAP3 family member 3
BCLAF3
234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04399 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC87094 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 3 (identifier: A2AJT9-3)
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti617S → G in BAC04399 (PubMed:14702039).Curated1
Sequence conflicti622Q → R in BAC04399 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025458592 – 711VKNVH…VATGI → GLALSPRLECGVTITAYCSL YLQDSSYLPPQPPE in isoform 3. 1 PublicationAdd BLAST120
Alternative sequenceiVSP_025459592 – 620Missing in isoform 2. 1 PublicationAdd BLAST29

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL772197 Genomic DNA No translation available.
AK094661 mRNA Translation: BAC04399.1 Different initiation.
AK127709 mRNA Translation: BAC87094.1 Different initiation.
BC126172 mRNA Translation: AAI26173.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14194.2 [A2AJT9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_938020.2, NM_198279.3 [A2AJT9-2]
XP_005274530.1, XM_005274473.3 [A2AJT9-1]
XP_011543777.1, XM_011545475.2 [A2AJT9-1]
XP_011543778.1, XM_011545476.2 [A2AJT9-1]
XP_011543779.1, XM_011545477.2 [A2AJT9-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000379682; ENSP00000369004; ENSG00000173681 [A2AJT9-1]
ENST00000379687; ENSP00000369009; ENSG00000173681 [A2AJT9-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
256643

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:256643

UCSC genome browser

More...
UCSCi
uc004czp.4, human [A2AJT9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772197 Genomic DNA No translation available.
AK094661 mRNA Translation: BAC04399.1 Different initiation.
AK127709 mRNA Translation: BAC87094.1 Different initiation.
BC126172 mRNA Translation: AAI26173.1
CCDSiCCDS14194.2 [A2AJT9-2]
RefSeqiNP_938020.2, NM_198279.3 [A2AJT9-2]
XP_005274530.1, XM_005274473.3 [A2AJT9-1]
XP_011543777.1, XM_011545475.2 [A2AJT9-1]
XP_011543778.1, XM_011545476.2 [A2AJT9-1]
XP_011543779.1, XM_011545477.2 [A2AJT9-2]

3D structure databases

SMRiA2AJT9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi129173, 3 interactors
IntActiA2AJT9, 3 interactors
STRINGi9606.ENSP00000369009

PTM databases

iPTMnetiA2AJT9
PhosphoSitePlusiA2AJT9

Genetic variation databases

BioMutaiBCLAF3

Proteomic databases

EPDiA2AJT9
jPOSTiA2AJT9
MassIVEiA2AJT9
MaxQBiA2AJT9
PaxDbiA2AJT9
PeptideAtlasiA2AJT9
PRIDEiA2AJT9
ProteomicsDBi405 [A2AJT9-1]
406 [A2AJT9-2]
407 [A2AJT9-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
9758, 34 antibodies

Genome annotation databases

EnsembliENST00000379682; ENSP00000369004; ENSG00000173681 [A2AJT9-1]
ENST00000379687; ENSP00000369009; ENSG00000173681 [A2AJT9-2]
GeneIDi256643
KEGGihsa:256643
UCSCiuc004czp.4, human [A2AJT9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
256643

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BCLAF3
HGNCiHGNC:27413, BCLAF3
HPAiENSG00000173681, Low tissue specificity
neXtProtiNX_A2AJT9
OpenTargetsiENSG00000173681
PharmGKBiPA134885371
VEuPathDBiHostDB:ENSG00000173681.16

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S4TN, Eukaryota
GeneTreeiENSGT00950000183163
HOGENOMiCLU_024256_0_0_1
InParanoidiA2AJT9
OMAiRESDCFN
OrthoDBi442192at2759
PhylomeDBiA2AJT9
TreeFamiTF335939

Enzyme and pathway databases

PathwayCommonsiA2AJT9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
256643, 7 hits in 618 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CXorf23, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
256643
PharosiA2AJT9, Tdark

Protein Ontology

More...
PROi
PR:A2AJT9
RNActiA2AJT9, protein

Gene expression databases

BgeeiENSG00000173681, Expressed in secondary oocyte and 167 other tissues
ExpressionAtlasiA2AJT9, baseline and differential
GenevisibleiA2AJT9, HS

Family and domain databases

InterProiView protein in InterPro
IPR029199, THRAP3_BCLAF1
PANTHERiPTHR15268, PTHR15268, 1 hit
PfamiView protein in Pfam
PF15440, THRAP3_BCLAF1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBCLA3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2AJT9
Secondary accession number(s): A1A4E8
, Q5VSM7, Q5VSN1, Q6ZS60, Q8N1W7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: February 20, 2007
Last modified: April 7, 2021
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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