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UniProtKB - A2AJT9 (BCLA3_HUMAN)

Entry version 103 (25 May 2022)
Sequence version 1 (20 Feb 2007)
Previous versions | rss
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Protein

BCLAF1 and THRAP3 family member 3

Gene

BCLAF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		A2AJT9

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		A2AJT9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BCLAF1 and THRAP3 family member 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BCLAF3Imported
Synonyms:CXorf23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:27413, BCLAF3

neXtProt; the human protein knowledge platform

More...neXtProti		NX_A2AJT9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000173681

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000173681

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134885371

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		A2AJT9, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		BCLAF3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002874341 – 711BCLAF1 and THRAP3 family member 3Add BLAST711

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei15PhosphoserineCombined sources1
Modified residuei17PhosphoserineCombined sources1
Modified residuei78PhosphoserineCombined sources1
Modified residuei80PhosphoserineCombined sources1
Modified residuei187PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki400Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei402PhosphoserineCombined sources1
Modified residuei578PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		A2AJT9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		A2AJT9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		A2AJT9

MaxQB - The MaxQuant DataBase

More...MaxQBi		A2AJT9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A2AJT9

PeptideAtlas

More...PeptideAtlasi		A2AJT9

PRoteomics IDEntifications database

More...PRIDEi		A2AJT9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		405 [A2AJT9-1]
406 [A2AJT9-2]
407 [A2AJT9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		A2AJT9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A2AJT9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000173681, Expressed in secondary oocyte and 167 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A2AJT9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A2AJT9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000173681, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		129173, 3 interactors

Protein interaction database and analysis system

More...IntActi		A2AJT9, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000369009

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		A2AJT9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		A2AJT9

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 42DisorderedSequence analysisAdd BLAST42
Regioni48 – 67DisorderedSequence analysisAdd BLAST20
Regioni94 – 350DisorderedSequence analysisAdd BLAST257
Regioni371 – 404DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi17 – 42Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi119 – 149Basic and acidic residuesSequence analysisAdd BLAST31
Compositional biasi163 – 246Basic and acidic residuesSequence analysisAdd BLAST84
Compositional biasi261 – 316Basic and acidic residuesSequence analysisAdd BLAST56
Compositional biasi325 – 346Basic and acidic residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BCLAF1/THRAP3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S4TN, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000183163

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_024256_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A2AJT9

Identification of Orthologs from Complete Genome Data

More...OMAi		KWHEDEF

Database of Orthologous Groups

More...OrthoDBi		442192at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A2AJT9

TreeFam database of animal gene trees

More...TreeFami		TF335939

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029199, THRAP3_BCLAF1

The PANTHER Classification System

More...PANTHERi		PTHR15268, PTHR15268, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15440, THRAP3_BCLAF1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A2AJT9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MARSRSRSPR WKHRSLSPVP RNAEHYKQRH SHGHYGCEYR KDPKRPVAWR 
        60         70         80         90        100
MDSEKHGQSK PRIPSRGNIY YQSYEHRSPS PNIRNSLENV YMYKPHRGYS 
       110        120        130        140        150
PGRGDSNRRA QYMPKYSEGI PYKEHERNSY PQKVQGGHSP DDHRVRGSGK 
       160        170        180        190        200
GGKPPQRSIA DSFRFEGKWH EDELRHQRIQ EEKYSQSTRR GSEDFETRSS 
       210        220        230        240        250
FQKRYPEDRD FRKYGHTSKR PKDVERYESR EPARNPKWKP EHSLPPYQED 
       260        270        280        290        300
TDQWNLGPQT YRHAEREHPE TSSATKVSYD YRHKRPKLLD GDQDFSDGRT 
       310        320        330        340        350
QKYCKEEDRK YSFQKGPLNR ELDCFNTGRG RETQDGQVKE PFKPSKKDSI 
       360        370        380        390        400
ACTYSNKNDV DLRSSNDKWK EKIKKEGDCR KESNSSSNQL DKSQKLPDVK 
       410        420        430        440        450
PSPINLRKKS LTVKVDVKKT VDTFRVASSY STERQMSHDL VAVGRKSENF 
       460        470        480        490        500
HPVFEHLDST QNTENKPTGE FAQEIITIIH QVKANYFPSP GITLHERFST 
       510        520        530        540        550
MQDIHKADVN EIPLNSDPEI HRRIDMSLAE LQSKQAVIYE SEQTLIKIID 
       560        570        580        590        600
PNDLRHDIER RRKERLQNED EHIFHIASAA ERDDQNSSFS KVKNVHTDGF 
       610        620        630        640        650
QKPTHFIKSN FRKCIEKPYM NYTTQRKDII THKPFEVEGN HRNTRVRPFK 
       660        670        680        690        700
SNFRGGRCQP NYKSGLVQKS LYIQAKYQRL RFTGPRGFIT HKFRERLMRK 
       710 
KKEYTDVATG I
Length:711
Mass (Da):83,871
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED389DC27B6C2D1B
GO
Isoform 2 (identifier: A2AJT9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     592-620: Missing.

Show »
Length:682
Mass (Da):80,395
Checksum:iC1373DE270D5966D
GO
Isoform 3 (identifier: A2AJT9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     592-711: VKNVHTDGFQ...KEYTDVATGI → GLALSPRLECGVTITAYCSLYLQDSSYLPPQPPE

Show »
Length:625
Mass (Da):73,187
Checksum:i435AB65759C38A26
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z385F2Z385_HUMAN
BCLAF1 and THRAP3 family member 3
BCLAF3
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BXX2H7BXX2_HUMAN
BCLAF1 and THRAP3 family member 3
BCLAF3
234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04399 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC87094 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 3 (identifier: A2AJT9-3)
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti617S → G in BAC04399 (PubMed:14702039).Curated1
Sequence conflicti622Q → R in BAC04399 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025458592 – 711VKNVH…VATGI → GLALSPRLECGVTITAYCSL YLQDSSYLPPQPPE in isoform 3. 1 PublicationAdd BLAST120
Alternative sequenceiVSP_025459592 – 620Missing in isoform 2. 1 PublicationAdd BLAST29

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL772197 Genomic DNA No translation available.
AK094661 mRNA Translation: BAC04399.1 Different initiation.
AK127709 mRNA Translation: BAC87094.1 Different initiation.
BC126172 mRNA Translation: AAI26173.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14194.2 [A2AJT9-2]

NCBI Reference Sequences

More...RefSeqi		NP_938020.2, NM_198279.3 [A2AJT9-2]
XP_005274530.1, XM_005274473.3 [A2AJT9-1]
XP_011543777.1, XM_011545475.2 [A2AJT9-1]
XP_011543778.1, XM_011545476.2 [A2AJT9-1]
XP_011543779.1, XM_011545477.2 [A2AJT9-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000379682.9; ENSP00000369004.4; ENSG00000173681.17
ENST00000379687.8; ENSP00000369009.3; ENSG00000173681.17 [A2AJT9-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		256643

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:256643

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000379682.9; ENSP00000369004.4; NM_001367774.2; NP_001354703.1

UCSC genome browser

More...UCSCi		uc004czp.4, human [A2AJT9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772197 Genomic DNA No translation available.
AK094661 mRNA Translation: BAC04399.1 Different initiation.
AK127709 mRNA Translation: BAC87094.1 Different initiation.
BC126172 mRNA Translation: AAI26173.1
CCDSiCCDS14194.2 [A2AJT9-2]
RefSeqiNP_938020.2, NM_198279.3 [A2AJT9-2]
XP_005274530.1, XM_005274473.3 [A2AJT9-1]
XP_011543777.1, XM_011545475.2 [A2AJT9-1]
XP_011543778.1, XM_011545476.2 [A2AJT9-1]
XP_011543779.1, XM_011545477.2 [A2AJT9-2]

3D structure databases

AlphaFoldDBiA2AJT9
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi129173, 3 interactors
IntActiA2AJT9, 3 interactors
STRINGi9606.ENSP00000369009

PTM databases

iPTMnetiA2AJT9
PhosphoSitePlusiA2AJT9

Genetic variation databases

BioMutaiBCLAF3

Proteomic databases

EPDiA2AJT9
jPOSTiA2AJT9
MassIVEiA2AJT9
MaxQBiA2AJT9
PaxDbiA2AJT9
PeptideAtlasiA2AJT9
PRIDEiA2AJT9
ProteomicsDBi405 [A2AJT9-1]
406 [A2AJT9-2]
407 [A2AJT9-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		9758, 34 antibodies from 11 providers

The DNASU plasmid repository

More...DNASUi		256643

Genome annotation databases

EnsembliENST00000379682.9; ENSP00000369004.4; ENSG00000173681.17
ENST00000379687.8; ENSP00000369009.3; ENSG00000173681.17 [A2AJT9-2]
GeneIDi256643
KEGGihsa:256643
MANE-SelectiENST00000379682.9; ENSP00000369004.4; NM_001367774.2; NP_001354703.1
UCSCiuc004czp.4, human [A2AJT9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		256643

GeneCards: human genes, protein and diseases

More...GeneCardsi		BCLAF3
HGNCiHGNC:27413, BCLAF3
HPAiENSG00000173681, Low tissue specificity
neXtProtiNX_A2AJT9
OpenTargetsiENSG00000173681
PharmGKBiPA134885371
VEuPathDBiHostDB:ENSG00000173681

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502S4TN, Eukaryota
GeneTreeiENSGT00950000183163
HOGENOMiCLU_024256_0_0_1
InParanoidiA2AJT9
OMAiKWHEDEF
OrthoDBi442192at2759
PhylomeDBiA2AJT9
TreeFamiTF335939

Enzyme and pathway databases

PathwayCommonsiA2AJT9
SignaLinkiA2AJT9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		256643, 12 hits in 694 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CXorf23, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		256643
PharosiA2AJT9, Tdark

Protein Ontology

More...PROi		PR:A2AJT9
RNActiA2AJT9, protein

Gene expression databases

BgeeiENSG00000173681, Expressed in secondary oocyte and 167 other tissues
ExpressionAtlasiA2AJT9, baseline and differential
GenevisibleiA2AJT9, HS

Family and domain databases

InterProiView protein in InterPro
IPR029199, THRAP3_BCLAF1
PANTHERiPTHR15268, PTHR15268, 1 hit
PfamiView protein in Pfam
PF15440, THRAP3_BCLAF1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBCLA3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2AJT9
Secondary accession number(s): A1A4E8
, Q5VSM7, Q5VSN1, Q6ZS60, Q8N1W7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: February 20, 2007
Last modified: May 25, 2022
This is version 103 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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