UniProtKB - A2AI40 (A2AI40_MOUSE)
Protein
Origin recognition complex subunit 4
Gene
Orc4
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
GO - Biological processi
- DNA replication Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Origin recognition complex subunit 4ARBA annotation |
Gene namesi | Name:Orc4Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1347043, Orc4 |
Subcellular locationi
Nucleus
- nucleus Source: InterPro
Other locations
- origin recognition complex Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000026761, Expressed in otic placode and 296 other tissues |
ExpressionAtlasi | A2AI40, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 199 | AAAInterPro annotationAdd BLAST | 143 |
Phylogenomic databases
GeneTreei | ENSGT00390000016542 |
HOGENOMi | CLU_007115_0_0_1 |
OMAi | KEWAING |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041664, AAA_16 IPR016527, ORC4 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12087, PTHR12087, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
A2AI40-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSRKTKSNA HAECLSQVQR ILRERFCHHS PHSNLFGVQV QYKHLIELLK
60 70 80 90 100
RTAIYGESNS VLIVGPRGSG KTTLLNHALK ELMEIEVSEN VIQVHLNGLL
110 120 130 140 150
QTNEKIALKE ITRQLNLDNV VEDKVFGSFA ENLSFLLEAL QKGDRTSSCP
160 170 180 190 200
VIFILDEFDI FAHQKNQTLL YNLFDISQSA QTPVAVIGLT CRLDILELLE
210 220 230
KRVKSRFSHR QIHLMNSFDF PQYLKIFKEQ LSLPAEF
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO88708 | ORC4_MOUSE | Origin recognition complex subunit ... | Orc4 Orc4l | 433 | Annotation score: | ||
Q9CZF7 | Q9CZF7_MOUSE | Origin recognition complex subunit ... | Orc4 Orc4l | 138 | Annotation score: | ||
A2AI43 | A2AI43_MOUSE | Origin recognition complex subunit ... | Orc4 | 72 | Annotation score: | ||
A2AI42 | A2AI42_MOUSE | Origin recognition complex subunit ... | Orc4 | 49 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 237 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL732317 Genomic DNA No translation available. AL845521 Genomic DNA No translation available. BX284644 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000142851; ENSMUSP00000119274; ENSMUSG00000026761 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL732317 Genomic DNA No translation available. AL845521 Genomic DNA No translation available. BX284644 Genomic DNA No translation available. |
3D structure databases
SMRi | A2AI40 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A2AI40 |
PRIDEi | A2AI40 |
Protocols and materials databases
Antibodypediai | 4189, 231 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000142851; ENSMUSP00000119274; ENSMUSG00000026761 |
Organism-specific databases
MGIi | MGI:1347043, Orc4 |
Phylogenomic databases
GeneTreei | ENSGT00390000016542 |
HOGENOMi | CLU_007115_0_0_1 |
OMAi | KEWAING |
Miscellaneous databases
ChiTaRSi | Orc4, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000026761, Expressed in otic placode and 296 other tissues |
ExpressionAtlasi | A2AI40, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR041664, AAA_16 IPR016527, ORC4 IPR027417, P-loop_NTPase |
PANTHERi | PTHR12087, PTHR12087, 1 hit |
Pfami | View protein in Pfam PF13191, AAA_16, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A2AI40_MOUSE | |
Accessioni | A2AI40Primary (citable) accession number: A2AI40 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 20, 2007 |
Last sequence update: | October 5, 2016 | |
Last modified: | August 12, 2020 | |
This is version 101 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |