UniProtKB - A2AHJ2 (A2AHJ2_MOUSE)
Protein
Submitted name:
Toll-like receptor 7
Gene
Tlr7
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- single-stranded RNA binding Source: InterPro
- transmembrane signaling receptor activity Source: InterPro
GO - Biological processi
- defense response to virus Source: InterPro
- immune response Source: InterPro
- MyD88-dependent toll-like receptor signaling pathway Source: InterPro
- toll-like receptor 7 signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Toll-like receptor 7Imported |
Gene namesi | Name:Tlr7Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
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Organism-specific databases
MGIi | MGI:2176882, Tlr7 |
Subcellular locationi
Other locations
- integral component of membrane Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000044583, Expressed in bone marrow macrophage and 125 other tissues |
ExpressionAtlasi | A2AHJ2, baseline and differential |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00940000159771 |
Family and domain databases
InterProi | View protein in InterPro IPR026880, TLR7 |
PANTHERi | PTHR47410:SF2, PTHR47410:SF2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
A2AHJ2-1 [UniParc]FASTAAdd to basket
10 20 30 40
MAQWVFSMWT RKRQILIFLN MLLVSRVFGF RWFPKTLPCE VKVNIPE
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP58681 | TLR7_MOUSE | Toll-like receptor 7 | Tlr7 | 1,050 | Annotation score: | ||
A2AHJ1 | A2AHJ1_MOUSE | Toll-like receptor 7 | Tlr7 | 49 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 47 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL731735 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000137492; ENSMUSP00000120922; ENSMUSG00000044583 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL731735 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | A2AHJ2 |
Protocols and materials databases
Antibodypediai | 8500, 977 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000137492; ENSMUSP00000120922; ENSMUSG00000044583 |
Organism-specific databases
MGIi | MGI:2176882, Tlr7 |
Phylogenomic databases
GeneTreei | ENSGT00940000159771 |
Miscellaneous databases
ChiTaRSi | Tlr7, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000044583, Expressed in bone marrow macrophage and 125 other tissues |
ExpressionAtlasi | A2AHJ2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR026880, TLR7 |
PANTHERi | PTHR47410:SF2, PTHR47410:SF2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A2AHJ2_MOUSE | |
Accessioni | A2AHJ2Primary (citable) accession number: A2AHJ2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 20, 2007 |
Last sequence update: | February 20, 2007 | |
Last modified: | October 7, 2020 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |