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Protein
Submitted name:

Potassium channel subfamily T member 1

Gene

Kcnt1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium channel subfamily T member 1Imported
Gene namesi
Name:Kcnt1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1924627 Kcnt1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei98 – 117HelicalSequence analysisAdd BLAST20
Transmembranei155 – 176HelicalSequence analysisAdd BLAST22
Transmembranei188 – 209HelicalSequence analysisAdd BLAST22
Transmembranei252 – 273HelicalSequence analysisAdd BLAST22
Transmembranei279 – 298HelicalSequence analysisAdd BLAST20
Transmembranei310 – 335HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiA2AHB7
PRIDEiA2AHB7

Expressioni

Gene expression databases

BgeeiENSMUSG00000058740 Expressed in 112 organ(s), highest expression level in cerebellum
ExpressionAtlasiA2AHB7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA2AHB7
SMRiA2AHB7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini260 – 327Ion_trans_2InterPro annotationAdd BLAST68

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3193 Eukaryota
ENOG410XSMA LUCA
GeneTreeiENSGT00530000063026
HOGENOMiHOG000231460
HOVERGENiHBG055190

Family and domain databases

InterProiView protein in InterPro
IPR003929 K_chnl_BK_asu
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF03493 BK_channel_a, 1 hit
PF07885 Ion_trans_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A2AHB7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARAKLPRSP SEGKAGPGDT PAGAAAPEEP HGLSPLLPAR GGGSVGSDVG
60 70 80 90 100
QRLHVEDFSL DSSLSQVQVE FYVNENTFKE RLKLFFIKNQ RSSLRIRLFN
110 120 130 140 150
FSLKLLTCLL YIVRVLLDNP DQGIGCWGCT KYNYTFNGSS SEFHWAPILW
160 170 180 190 200
VERKMALWVI QVIVATISFL ETMLIIYLSY KGNIWEQIFH VSFVLEMINT
210 220 230 240 250
LPFIITVFWP PLRNLFIPVF LNCWLAKHAL ENMINDFHRA ILRTQSAMFN
260 270 280 290 300
QVLILFCTLL CLVFTGTCGI QHLERAGGNL NLLTSFYFCI VTFSTVGFGD
310 320 330 340 350
VTPKIWPSQL LVVILICVTL VVLPLQFEEL VYLWMERQKS GGNYSRHRAR
360 370 380 390 400
TEKHVVLCVS SLKIDLLMDF LNEFYAHPRL QDYYVVILCP SEMDVQVRRV
410 420 430 440 450
LQIPLWSQRV IYLQGSALKD QDLMRAKMDN GEACFILSSR NEVDRTAADH
460 470 480 490 500
QTILRAWAVK DFAPNCPLYV QILKPENKFH VKFADHVVCE EECKYAMLAL
510 520 530 540 550
NCICPATSTL ITLLVHTSRG QEGQESPEQW QRTYGRCSGN EVYHIRMGDS
560 570 580 590 600
KFFREYEGKS FTYAAFHAHK KYGVCLIGLK REENKSILLN PGPRHILAAS
610 620 630 640 650
DTCFYINITK EENSAFIFKQ EEKQKRRGLA GQALYEGPSR LPVHSIIASM
660 670 680 690 700
GTVAMDLQNT DCRPSQGGSG GDGTKLTLPT ENGSGSRRPS IAPVLELADS
710 720 730 740 750
SALLPCDLLS DQSEDEVTPS DDEGLSVVEY VKGYPPNSPY IGSSPTLCHL
760 770 780 790 800
LPVKAPFCCL RLDKGCKHNS YEDAKAYGFK NKLIIVSAET AGNGLYNFIV
810 820 830 840 850
PLRAYYRSRR ELNPIVLLLD NKPDHHFLEA ICCFPMVYYM EGSVDNLDSL
860 870 880 890 900
LQCGIIYADN LVVVDKESTM SAEEDYMADA KTIVNVQTMF RLFPSLSITT
910 920 930 940 950
ELTHPSNMRF MQFRAKDSYS LALSKLEKQE RENGSNLAFM FRLPFAAGRV
960 970 980 990 1000
FSISMLDTLL YQSFVKDYMI TITRLLLGLD TTPGSGYLCA MKVTEDDLWI
1010 1020 1030 1040 1050
RTYGRLFQKL CSSSAEIPIG IYRTECHVFS EPHDVRAQSQ ISVNMEDCED
1060 1070 1080 1090 1100
TREAKGPWGT RAASGSGSTH GRHGGSADPV EHPLLRRKSL QWARKLSRKS
1110 1120 1130 1140 1150
TKQAGKAPVA TDWITQQRLS LYRRSERQEL SELVKNRMKH LGLPTTGYDE
1160 1170 1180 1190 1200
MNDHHQNTLS YVLINPPPDT RLEPNDIVYL IRSDPLAHVA SSSQSRKSSC
1210
SNKLSSCNPE TRDETQL
Length:1,217
Mass (Da):137,360
Last modified:February 20, 2007 - v1
Checksum:i190BDDC60CF75ED3
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6ZPR4KCNT1_MOUSE
Potassium channel subfamily T membe...
Kcnt1 Kiaa1422
1,224Annotation score:
A2AHB8A2AHB8_MOUSE
Potassium channel subfamily T membe...
Kcnt1
1,238Annotation score:
C0KTP6C0KTP6_MOUSE
Potassium channel subfamily T membe...
Kcnt1
1,218Annotation score:
A2AHB9A2AHB9_MOUSE
Potassium channel subfamily T membe...
Kcnt1
1,236Annotation score:
A0A0G2JER3A0A0G2JER3_MOUSE
Potassium channel subfamily T membe...
Kcnt1
1,183Annotation score:
A0A0G2JG99A0A0G2JG99_MOUSE
Potassium channel subfamily T membe...
Kcnt1
1,202Annotation score:
A0A0G2JG91A0A0G2JG91_MOUSE
Potassium channel subfamily T membe...
Kcnt1
36Annotation score:
A0A0G2JDW4A0A0G2JDW4_MOUSE
Potassium channel subfamily T membe...
Kcnt1
330Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731682 Genomic DNA No translation available.
RefSeqiXP_017172686.1, XM_017317197.1
UniGeneiMm.119462

Genome annotation databases

EnsembliENSMUST00000114176; ENSMUSP00000109813; ENSMUSG00000058740
GeneIDi227632

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731682 Genomic DNA No translation available.
RefSeqiXP_017172686.1, XM_017317197.1
UniGeneiMm.119462

3D structure databases

ProteinModelPortaliA2AHB7
SMRiA2AHB7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA2AHB7
PRIDEiA2AHB7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114176; ENSMUSP00000109813; ENSMUSG00000058740
GeneIDi227632

Organism-specific databases

CTDi57582
MGIiMGI:1924627 Kcnt1

Phylogenomic databases

eggNOGiKOG3193 Eukaryota
ENOG410XSMA LUCA
GeneTreeiENSGT00530000063026
HOGENOMiHOG000231460
HOVERGENiHBG055190

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000058740 Expressed in 112 organ(s), highest expression level in cerebellum
ExpressionAtlasiA2AHB7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003929 K_chnl_BK_asu
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF03493 BK_channel_a, 1 hit
PF07885 Ion_trans_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2AHB7_MOUSE
AccessioniPrimary (citable) accession number: A2AHB7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: October 10, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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