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Protein
Submitted name:

Synaptotagmin-like protein 1

Gene

Sytl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-8854214 TBC/RABGAPs

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptotagmin-like protein 1Imported
Gene namesi
Name:Sytl1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1933365 Sytl1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiA2AE94
PeptideAtlasiA2AE94
PRIDEiA2AE94

Expressioni

Gene expression databases

BgeeiENSMUSG00000028860 Expressed in 161 organ(s), highest expression level in esophagus
ExpressionAtlasiA2AE94 baseline and differential
GenevisibleiA2AE94 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA2AE94
SMRiA2AE94
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 87RabBDInterPro annotationAdd BLAST57
Domaini287 – 374C2InterPro annotationAdd BLAST88
Domaini427 – 517C2InterPro annotationAdd BLAST91

Phylogenomic databases

eggNOGiENOG410IT3I Eukaryota
ENOG41107B6 LUCA
GeneTreeiENSGT00810000125376
HOVERGENiHBG057965
KOiK17598
OMAiWDSEPTW
OrthoDBiEOG091G07OO
TreeFamiTF341184

Family and domain databases

Gene3Di2.60.40.150, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR010911 Rab_BD
IPR028378 Sytl1
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10024:SF11 PTHR10024:SF11, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
PS50916 RABBD, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A2AE94-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQRGHPSQE RLWALPSLPM AHGPGSEAEG LLDLSFLTEE EQEAISDVLK
60 70 80 90 100
RDAHLRQLEE GRVSKLRASL EDPWQLKILT GDWFQEARSQ RHHHAHFGSD
110 120 130 140 150
LVRASIRRKK SPKGDQALGS DGEAEAAGEN TIEGEPESRV SIEVAAPERN
160 170 180 190 200
TETQGPDLFS PYVPSKASEG QEEEPQDQEC ELEAPGEGGV QVAEADPELD
210 220 230 240 250
PEQKAEQESQ PTPAQSKATS KILENGEEAP GLGPSLDRML SSSSSVSSLN
260 270 280 290 300
SSTLSGSLMS LSGEAEAGTV QVRGSVLFSL RYEPGTSELR VQVIQCQGLA
310 320 330 340 350
AARRRRSDPY VKSYLLPDKQ SKRKTSVKKR NLNPIFNETL RHSVQQADLP
360 370 380 390 400
GRVLSLSVWH RESLGRNIFL GEVEVPLDTW NWDSEATWLP LQPRVPPSPD
410 420 430 440 450
ELPSRGLLSL SLKYVPAGSE GGGQPQSGEL HFWVKEAQSL VPLRPGSLDT
460 470 480 490 500
YIQCSVLPDD SRASRQRTRV VRRSLSPVFN HTMVYDGFGP ADLRQACAEL
510 520 530 540 550
SLWDHGALAS RQLGGTRLSL GTGSSYGLQV PWMDSTPEEK QLWQTLLERP
560
CEWVDGLLPL RTNLVPRA
Length:568
Mass (Da):62,501
Last modified:February 20, 2007 - v1
Checksum:i62A45A3B58E43976
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99N80SYTL1_MOUSE
Synaptotagmin-like protein 1
Sytl1 Slp1
567Annotation score:
A2AE95A2AE95_MOUSE
Synaptotagmin-like protein 1
Sytl1
503Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671882 Genomic DNA No translation available.
RefSeqiNP_113570.2, NM_031393.2
XP_011248567.1, XM_011250265.1
UniGeneiMm.25660

Genome annotation databases

EnsembliENSMUST00000030674; ENSMUSP00000030674; ENSMUSG00000028860
GeneIDi269589
KEGGimmu:269589
UCSCiuc008vco.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671882 Genomic DNA No translation available.
RefSeqiNP_113570.2, NM_031393.2
XP_011248567.1, XM_011250265.1
UniGeneiMm.25660

3D structure databases

ProteinModelPortaliA2AE94
SMRiA2AE94
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiA2AE94
PeptideAtlasiA2AE94
PRIDEiA2AE94

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030674; ENSMUSP00000030674; ENSMUSG00000028860
GeneIDi269589
KEGGimmu:269589
UCSCiuc008vco.2 mouse

Organism-specific databases

CTDi84958
MGIiMGI:1933365 Sytl1

Phylogenomic databases

eggNOGiENOG410IT3I Eukaryota
ENOG41107B6 LUCA
GeneTreeiENSGT00810000125376
HOVERGENiHBG057965
KOiK17598
OMAiWDSEPTW
OrthoDBiEOG091G07OO
TreeFamiTF341184

Enzyme and pathway databases

ReactomeiR-MMU-8854214 TBC/RABGAPs

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028860 Expressed in 161 organ(s), highest expression level in esophagus
ExpressionAtlasiA2AE94 baseline and differential
GenevisibleiA2AE94 MM

Family and domain databases

Gene3Di2.60.40.150, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR010911 Rab_BD
IPR028378 Sytl1
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10024:SF11 PTHR10024:SF11, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
PS50916 RABBD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2AE94_MOUSE
AccessioniPrimary (citable) accession number: A2AE94
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: September 12, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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