UniProtKB - A2ADF7 (S2534_MOUSE)
Protein
Solute carrier family 25 member 34
Gene
Slc25a34
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Biological processi
- blastocyst hatching Source: MGI
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Solute carrier family 25 member 34 |
Gene namesi | Name:Slc25a34 Synonyms:Gm1369 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2686215, Slc25a34 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Multi-pass membrane protein By similarity
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
- mitochondrion Source: MGI
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 41 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 59 – 79 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 112 – 134 | Helical; Name=3Sequence analysisAdd BLAST | 23 | |
Transmembranei | 184 – 205 | Helical; Name=4Sequence analysisAdd BLAST | 22 | |
Transmembranei | 220 – 240 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 292 – 315 | Helical; Name=6Sequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000291790 | 1 – 318 | Solute carrier family 25 member 34Add BLAST | 318 |
Proteomic databases
PaxDbi | A2ADF7 |
PRIDEi | A2ADF7 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000040740, Expressed in heart and 44 other tissues |
Genevisiblei | A2ADF7, MM |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000039188 |
Miscellaneous databases
RNActi | A2ADF7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 18 – 111 | Solcar 1Add BLAST | 94 | |
Repeati | 115 – 208 | Solcar 2Add BLAST | 94 | |
Repeati | 218 – 309 | Solcar 3Add BLAST | 92 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0755, Eukaryota |
GeneTreei | ENSGT00940000160016 |
HOGENOMi | CLU_015166_14_3_1 |
InParanoidi | A2ADF7 |
OMAi | ICQQEGP |
OrthoDBi | 1013743at2759 |
PhylomeDBi | A2ADF7 |
TreeFami | TF324506 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: A2ADF7-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MKPTQAQMAP AMDSREMVSP AVDLVLGASA CCLACVFTNP LEVVKTRLQL
60 70 80 90 100
QGELQAPGTY PRPYRGFVSS VAAVARADGL WGLQKGLAAG LLYQGLMNGV
110 120 130 140 150
RFYCYSLACQ AGLTQQPGGT VVAGAAAGAL GAFVGSPAYL VKTQLQAQTV
160 170 180 190 200
ATMAVGHQHQ HQGVLSALET IWRQQGMLGL WRGVGGAVPR VTVGSAAQLA
210 220 230 240 250
TFTSAKAWVQ DRQWFLEDSW LVTLAGGMIS SIAVVAVMTP LDVVSTRLYN
260 270 280 290 300
QPVDRAGRGQ LYGGLADCLV KTCQQEGPLA LYKGLGPAYL RLGPHTILSM
310
FFWDELRKLV ARAQHQGT
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_026235 | 214 – 219 | WFLEDS → VRSWEH in isoform 2. 1 Publication | 6 | |
Alternative sequenceiVSP_026236 | 220 – 318 | Missing in isoform 2. 1 PublicationAdd BLAST | 99 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670446 Genomic DNA No translation available. BC089627 mRNA Translation: AAH89627.2 |
CCDSi | CCDS18878.1 [A2ADF7-1] |
RefSeqi | NP_001013802.1, NM_001013780.1 [A2ADF7-1] |
Genome annotation databases
Ensembli | ENSMUST00000038661; ENSMUSP00000039188; ENSMUSG00000040740 [A2ADF7-1] |
GeneIDi | 384071 |
KEGGi | mmu:384071 |
UCSCi | uc008vox.1, mouse [A2ADF7-1] uc008voy.1, mouse [A2ADF7-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL670446 Genomic DNA No translation available. BC089627 mRNA Translation: AAH89627.2 |
CCDSi | CCDS18878.1 [A2ADF7-1] |
RefSeqi | NP_001013802.1, NM_001013780.1 [A2ADF7-1] |
3D structure databases
SMRi | A2ADF7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000039188 |
Proteomic databases
PaxDbi | A2ADF7 |
PRIDEi | A2ADF7 |
Protocols and materials databases
Antibodypediai | 28971, 53 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000038661; ENSMUSP00000039188; ENSMUSG00000040740 [A2ADF7-1] |
GeneIDi | 384071 |
KEGGi | mmu:384071 |
UCSCi | uc008vox.1, mouse [A2ADF7-1] uc008voy.1, mouse [A2ADF7-2] |
Organism-specific databases
CTDi | 284723 |
MGIi | MGI:2686215, Slc25a34 |
Phylogenomic databases
eggNOGi | KOG0755, Eukaryota |
GeneTreei | ENSGT00940000160016 |
HOGENOMi | CLU_015166_14_3_1 |
InParanoidi | A2ADF7 |
OMAi | ICQQEGP |
OrthoDBi | 1013743at2759 |
PhylomeDBi | A2ADF7 |
TreeFami | TF324506 |
Miscellaneous databases
BioGRID-ORCSi | 384071, 0 hits in 17 CRISPR screens |
PROi | PR:A2ADF7 |
RNActi | A2ADF7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000040740, Expressed in heart and 44 other tissues |
Genevisiblei | A2ADF7, MM |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | S2534_MOUSE | |
Accessioni | A2ADF7Primary (citable) accession number: A2ADF7 Secondary accession number(s): Q5FW51 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2007 |
Last sequence update: | February 20, 2007 | |
Last modified: | December 2, 2020 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families