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Protein
Submitted name:

Protein SOGA1

Gene

Soga1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protein SOGA1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Soga1Imported
Synonyms:9830001H06RikImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444575 Soga1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2ACV6

PeptideAtlas

More...
PeptideAtlasi
A2ACV6

PRoteomics IDEntifications database

More...
PRIDEi
A2ACV6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2ACV6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000055485 Expressed in 131 organ(s), highest expression level in cerebellum

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2ACV6 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A2ACV6, 18 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A2ACV6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2ACV6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1065 – 1203DUF4482InterPro annotationAdd BLAST139

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili216 – 243Sequence analysisAdd BLAST28
Coiled coili245 – 279Sequence analysisAdd BLAST35
Coiled coili308 – 349Sequence analysisAdd BLAST42
Coiled coili400 – 420Sequence analysisAdd BLAST21
Coiled coili448 – 482Sequence analysisAdd BLAST35
Coiled coili505 – 546Sequence analysisAdd BLAST42
Coiled coili816 – 843Sequence analysisAdd BLAST28
Coiled coili991 – 1011Sequence analysisAdd BLAST21
Coiled coili1079 – 1113Sequence analysisAdd BLAST35

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4787 Eukaryota
ENOG410XUHJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158158

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231278

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080205

Identification of Orthologs from Complete Genome Data

More...
OMAi
YSRWLCN

Database of Orthologous Groups

More...
OrthoDBi
34629at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2ACV6

TreeFam database of animal gene trees

More...
TreeFami
TF331853

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027882 DUF4482
IPR027881 SOGA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14818 DUF4482, 1 hit
PF11365 SOGA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A2ACV6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METPAGESSA RGYGPPPAPA PAAERKKSHR APSPARPKDV AGWSLAKGRR
60 70 80 90 100
GTGPGSATAC GTASSARPDK KGRAVAPGTR GTGPRVAGVR TGVRAKGRPR
110 120 130 140 150
PGTGPRPPPP PPSLTDSSSE VSDCASEEAR QLGLELALSS DAESAAGGPA
160 170 180 190 200
GTRTGQPPQP AQSGQQPPRP PASPDEPSVA ASSVGSSRLP LSASLAFSDL
210 220 230 240 250
TEEMLDCGPG GLVRELEELR SENDYLKDEI EELRAEMLEM RDVYMEEDVY
260 270 280 290 300
QLQELRQQLD QASKTCRILQ YRLRKAERRS LRAAQTGQVD GELIRGLEQD
310 320 330 340 350
VKVSKDISMR LHKELEVVEK KRMRLEEENE GLRQRLIETE LAKQVLQTEL
360 370 380 390 400
DRPREHSLKK RGTRSLGKTD KKPTAQEDSA DLKCQLHFAK EESALMCKKL
410 420 430 440 450
TKLAKENDSM KEELLKYRSL YGDLDAALSA EELADAPHSR ETELKVHLKL
460 470 480 490 500
VEEEANLLSR RIVELEVENR GLRAEMDDMK DHGGGGGPEA RLAFSSLGGE
510 520 530 540 550
CGESLAELRR HLQFVEEEAE LLRRSSAELE DQNKLLLNEL AKYRSEHELD
560 570 580 590 600
VTLSEDSCSV LSEPSQEELA AAKLQIGELS GKVKKLQYEN RVLLSNLQRC
610 620 630 640 650
DLASCQSTRP MLETDAEAGD SAQCVPAPLG ETLEPHAARL CRAREAEALP
660 670 680 690 700
GLREQAALVS KAIDVLVADA NGFSVGLRLC LDNECADLRL HEAPDNSEGP
710 720 730 740 750
RDAKLIHAIL VRLSVLQQEL NAFTRKADVA LGSSGKEQPE PFPALPALGS
760 770 780 790 800
QGPAKEIMLS KDLGSDFQPP DFRDLLEWEP RIREAFRTGD LESKPDPSRN
810 820 830 840 850
FRPYRAEDND SYASEIKDLQ LVLAEAHDSL RGLQEQLSQE RQLRKEEADS
860 870 880 890 900
FNQKMVQLKE DQQRALLRRE FELQSLSLQR RLEQKFWSQE KNILVQESQQ
910 920 930 940 950
FKHNFLLLFM KLRWFLKRWR QGKVLPSEED DFLEVNSMKE LYLLMEEEEM
960 970 980 990 1000
NAQHSDNKAC TGESWTQNTP NECIKTLADM KVTLKELCWL LQDERRGLTE
1010 1020 1030 1040 1050
LQQQFAKAKA TWETERAELK GHASQMELKA GKGASERPGP DWKAALQRER
1060 1070 1080 1090 1100
EEQQHLLAES YSAVMELTRQ LQLSERHWSQ EKLQLVERLQ GEKQQVEQQV
1110 1120 1130 1140 1150
KELQNRLSQL QKAAEPWVLK HSDMEKQDNS WKEARSEKTH DKEGVSEAEL
1160 1170 1180 1190 1200
GGTGLKRTKS VSSMSEFESL LDCSPYLAGG DARNKKLPNG PAFAFVSTEP
1210 1220 1230 1240 1250
VEPEKDAKEK AGLSTRDCSH IGSLACQEPA GRQMQRSYTA PDKTGIRVYY
1260 1270 1280 1290 1300
SPPVARRLGV PVVHDKEGKI LIEPGFLFTT AKPKESAEAD GLAESSYSRW
1310 1320 1330 1340 1350
LCNFSRQRLD GGSGASTSGS GPAFPALHDF EMSGNMSDDM KEITNCVRQA
1360 1370 1380 1390 1400
MRSGSLERKV KNTSSQTVGV ATVGTQTIRT VSVGLQTDPP RSSLHSKSWS
1410 1420 1430 1440 1450
PRSSSLVSVR SKQISSSLDK VHSRIERPCC SPKYGSPKLQ RRSVSKLDST
1460 1470 1480 1490 1500
KDRSLWNLHQ GKQNGSAWAR STTTRDSPVL RNINDGLSSL FSVVEHSGST
1510 1520 1530 1540 1550
ESVWKLGMSE ARTKPEPPKY GIVQEFFRNV CGRAPSPTTA AGEESCKKPE
1560 1570 1580 1590 1600
PLSPASYHQP EGVSRILNKK AAKAGGSEEV RPTMLSQVGK DGILRDGDGS
1610 1620 1630 1640 1650
LILPSEDAVC DCSAQSLASC FIRPSRNTIR HSPSKCRLHP SESGWGGEER

AAPQ
Length:1,654
Mass (Da):183,145
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6B14B640F9022498
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E1U8D0SOGA1_MOUSE
Protein SOGA1
Soga1 Soga
1,418Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL669932 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001158135.1, NM_001164663.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.79466

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000069098; ENSMUSP00000066556; ENSMUSG00000055485

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
320706

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:320706

UCSC genome browser

More...
UCSCi
uc008nol.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669932 Genomic DNA No translation available.
RefSeqiNP_001158135.1, NM_001164663.1
UniGeneiMm.79466

3D structure databases

ProteinModelPortaliA2ACV6
SMRiA2ACV6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA2ACV6, 18 interactors

PTM databases

iPTMnetiA2ACV6

Proteomic databases

MaxQBiA2ACV6
PeptideAtlasiA2ACV6
PRIDEiA2ACV6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000069098; ENSMUSP00000066556; ENSMUSG00000055485
GeneIDi320706
KEGGimmu:320706
UCSCiuc008nol.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
140710
MGIiMGI:2444575 Soga1

Phylogenomic databases

eggNOGiKOG4787 Eukaryota
ENOG410XUHJ LUCA
GeneTreeiENSGT00940000158158
HOGENOMiHOG000231278
HOVERGENiHBG080205
OMAiYSRWLCN
OrthoDBi34629at2759
PhylomeDBiA2ACV6
TreeFamiTF331853

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Soga1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000055485 Expressed in 131 organ(s), highest expression level in cerebellum
GenevisibleiA2ACV6 MM

Family and domain databases

InterProiView protein in InterPro
IPR027882 DUF4482
IPR027881 SOGA
PfamiView protein in Pfam
PF14818 DUF4482, 1 hit
PF11365 SOGA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2ACV6_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2ACV6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: January 16, 2019
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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