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Entry version 109 (07 Oct 2020)
Sequence version 1 (20 Feb 2007)
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Protein
Submitted name:

Arginine-glutamic acid dipeptide repeats protein

Gene

Rere

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Arginine-glutamic acid dipeptide repeats proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RereImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2683486, Rere

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

AcetylationARBA annotation, PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A2A7T3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2A7T3

PeptideAtlas

More...
PeptideAtlasi
A2A7T3

PRoteomics IDEntifications database

More...
PRIDEi
A2A7T3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000039852, Expressed in bone marrow and 323 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2A7T3, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2A7T3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 119ELM2InterPro annotationAdd BLAST104
Domaini123 – 175SANTInterPro annotationAdd BLAST53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 32DisorderedSequence analysisAdd BLAST32
Regioni196 – 227DisorderedSequence analysisAdd BLAST32
Regioni274 – 857DisorderedSequence analysisAdd BLAST584
Regioni886 – 970DisorderedSequence analysisAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi196 – 218PolarSequence analysisAdd BLAST23
Compositional biasi288 – 303PolyampholyteSequence analysisAdd BLAST16
Compositional biasi337 – 358PolarSequence analysisAdd BLAST22
Compositional biasi359 – 402PolyampholyteSequence analysisAdd BLAST44
Compositional biasi403 – 419PolarSequence analysisAdd BLAST17
Compositional biasi420 – 439PolyampholyteSequence analysisAdd BLAST20
Compositional biasi440 – 471PolarSequence analysisAdd BLAST32
Compositional biasi487 – 513Pro-richSequence analysisAdd BLAST27
Compositional biasi514 – 530PolarSequence analysisAdd BLAST17
Compositional biasi539 – 573Pro-richSequence analysisAdd BLAST35
Compositional biasi621 – 635PolarSequence analysisAdd BLAST15
Compositional biasi636 – 673Pro-richSequence analysisAdd BLAST38
Compositional biasi704 – 735Pro-richSequence analysisAdd BLAST32
Compositional biasi736 – 757PolarSequence analysisAdd BLAST22
Compositional biasi758 – 789Pro-richSequence analysisAdd BLAST32
Compositional biasi886 – 934PolyampholyteSequence analysisAdd BLAST49

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153615

Identification of Orthologs from Complete Genome Data

More...
OMAi
PCRRLNS

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00202, ZnF_GATA, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002951, Atrophin-like
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A2A7T3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDPFSPCRR LNSTQGEIRV GPSHQAKLPD LQPFPSPDGD TVTQHEELVW
60 70 80 90 100
MPGVSDCDLL MYLRAARSMA AFAGMCDGGS TEDGCVAASR DDTTLNALNT
110 120 130 140 150
LHESSYDAGK ALQRLVKKPV PKLIEKCWTE DEVKRFVKGL RQYGKNFFRI
160 170 180 190 200
RKELLPSKET GELITFYYYW KKTPEAASSR AHRRHRRQAV FRRIKTRTAS
210 220 230 240 250
TPVNTPSRPP SSEFLDLSSA SEDDFDSEDS EQELKGYACR HCFTTTSKDW
260 270 280 290 300
HHGGRENILL CTDCRIHFKK YGELPPIEKP VDPPPFMFKP VKEEDDGLSG
310 320 330 340 350
KHSMRTRRSR GSMSTLRSGR KKQPTSPDGR ASPINEDIRS SGRNSPSAAS
360 370 380 390 400
TSSNDSKAET VKKSAKKVKE EAASPLKSTK RQREKVASDT EDTDRITSKK
410 420 430 440 450
TKTQEISRPN SPSEGEGESS DSRSVNDEGS SDPKDIDQDN RSTSPSIPSP
460 470 480 490 500
QDNESDSDSS AQQQMLQAQP PALQAPSGAA SAPSTAPPGT PQLPTQGPTP
510 520 530 540 550
SATAVPPQGS PATSQPPNQT QSTVAPAAHT HIQQAPTLHP PRLPSPHPPL
560 570 580 590 600
QPMTAPPSQS SAQPHPQPSL HSQGPPGPHS LQTGPLLQHP GPPQPFGLPS
610 620 630 640 650
QPSQGQGPLG PSPAAAHPHS TIQLPASQSA LQPQQPPREQ PLPPAPLAMP
660 670 680 690 700
HIKPPPTTPI PQLPAPQAHK HPPHLSGPSP FSLNANLPPP PALKPLSSLS
710 720 730 740 750
THHPPSAHPP PLQLMPQSQP LPSSPAQPPG LTQSQSLPPP AASHPTTGLH
760 770 780 790 800
QVPSQSPFPQ HPFVPGGPPP ITPPSCPPTS TPPAGPSSSS QPPCSAAVSS
810 820 830 840 850
GGSVPGAPSC PLPAVQIKEE ALDEAEEPES PPPPPRSPSP EPTVVDTPSH
860 870 880 890 900
ASQSARFYKH LDRGYNSCAR TDLYFMPLAG SKLAKKREEA IEKAKREAEQ
910 920 930 940 950
KAREEREREK EKEKERERER EREREAERAA KASSSAHEGR LSDPQLSGPG
960 970 980 990 1000
HMRPSFEPPP TTIAAVPPYI GPDTPALRTL SEYARPHVMS PTNRNHPFYM
1010 1020 1030 1040 1050
PLNPTDPLLA YHMPGLYNVD PTIRERELRE REIREREIRE RELRERMKPG
1060 1070 1080 1090 1100
FEVKPPELDP LHPATNPMEH FARHSALTIP PAAGPHPFAS FHPGLNPLER
1110 1120 1130 1140 1150
ERLALAGPQL RPEMSYPDRL AAERIHAERM ASLTSDPLAR LQMFNVTPHH
1160 1170 1180 1190 1200
HQHSHIHSHL HLHQQDPLHQ GSAGPVHPLV DPLTAGPHLA RFPYPPGTLP
1210 1220 1230 1240 1250
NPLLGQPPHE HEMLRHPVFG TPYPRDLPGA IPPPMSAAHQ LQAMHAQSAE
1260 1270 1280 1290
LQRLAMEQQW LHGHPHMHGG HLPSQEDYYS RLKKEGDKQL
Length:1,290
Mass (Da):140,913
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i334B2F238EE7AD06
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q80TZ9RERE_MOUSE
Arginine-glutamic acid dipeptide re...
Rere Atr2, Kiaa0458
1,558Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AS11B1AS11_MOUSE
Arginine-glutamic acid dipeptide re...
Rere
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2P787A0A1W2P787_MOUSE
Arginine-glutamic acid dipeptide re...
Rere
435Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A7T1A2A7T1_MOUSE
Arginine-glutamic acid dipeptide re...
Rere
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL606903 Genomic DNA No translation available.
AL606982 Genomic DNA No translation available.
AL606988 Genomic DNA No translation available.
AL691453 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000105680; ENSMUSP00000101305; ENSMUSG00000039852

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606903 Genomic DNA No translation available.
AL606982 Genomic DNA No translation available.
AL606988 Genomic DNA No translation available.
AL691453 Genomic DNA No translation available.

3D structure databases

SMRiA2A7T3
ModBaseiSearch...

Proteomic databases

jPOSTiA2A7T3
MaxQBiA2A7T3
PeptideAtlasiA2A7T3
PRIDEiA2A7T3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
13215, 156 antibodies

Genome annotation databases

EnsembliENSMUST00000105680; ENSMUSP00000101305; ENSMUSG00000039852

Organism-specific databases

MGIiMGI:2683486, Rere

Phylogenomic databases

GeneTreeiENSGT00940000153615
OMAiPCRRLNS

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rere, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000039852, Expressed in bone marrow and 323 other tissues
ExpressionAtlasiA2A7T3, baseline and differential

Family and domain databases

CDDicd00202, ZnF_GATA, 1 hit
InterProiView protein in InterPro
IPR002951, Atrophin-like
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA
PfamiView protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit
SMARTiView protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2A7T3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2A7T3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: October 7, 2020
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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