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Entry version 95 (13 Feb 2019)
Sequence version 1 (20 Feb 2007)
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Protein

Zinc finger MYM-type protein 4

Gene

Zmym4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the regulation of cell morphology and cytoskeletal organization.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri362 – 402MYM-type 1Add BLAST41
Zinc fingeri414 – 457MYM-type 2Add BLAST44
Zinc fingeri464 – 499MYM-type 3Add BLAST36
Zinc fingeri510 – 544MYM-type 4Add BLAST35
Zinc fingeri554 – 592MYM-type 5Add BLAST39
Zinc fingeri600 – 631MYM-type 6Add BLAST32
Zinc fingeri708 – 742MYM-type 7Add BLAST35
Zinc fingeri749 – 788MYM-type 8Add BLAST40
Zinc fingeri795 – 829MYM-type 9Add BLAST35

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
  • zinc ion binding Source: InterPro

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger MYM-type protein 4
Alternative name(s):
Zinc finger protein 262
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zmym4
Synonyms:Kiaa0425, Zfp262, Znf262
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915035 Zmym4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002990182 – 1549Zinc finger MYM-type protein 4Add BLAST1548

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei106PhosphothreonineBy similarity1
Modified residuei109PhosphoserineBy similarity1
Modified residuei121PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki139Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki148Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei161PhosphoserineBy similarity1
Cross-linki195Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei197PhosphoserineBy similarity1
Cross-linki201Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki232Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei242PhosphoserineBy similarity1
Cross-linki250Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki250Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linki273Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki289Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki327Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki400Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki428Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki430Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1035Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1062Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1065PhosphoserineBy similarity1
Modified residuei1072PhosphoserineBy similarity1
Cross-linki1081Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1128Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1182PhosphoserineBy similarity1
Modified residuei1257PhosphoserineBy similarity1
Cross-linki1432Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1540PhosphoserineBy similarity1
Modified residuei1543PhosphoserineBy similarity1
Modified residuei1548PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A2A791

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2A791

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A2A791

PeptideAtlas

More...
PeptideAtlasi
A2A791

PRoteomics IDEntifications database

More...
PRIDEi
A2A791

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2A791

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A2A791

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000042446 Expressed in 284 organ(s), highest expression level in embryonic stem cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2A791 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2A791 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
212440, 1 interactor

Protein interaction database and analysis system

More...
IntActi
A2A791, 2 interactors

Molecular INTeraction database

More...
MINTi
A2A791

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000101714

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A2A791

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
A2A791

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri362 – 402MYM-type 1Add BLAST41
Zinc fingeri414 – 457MYM-type 2Add BLAST44
Zinc fingeri464 – 499MYM-type 3Add BLAST36
Zinc fingeri510 – 544MYM-type 4Add BLAST35
Zinc fingeri554 – 592MYM-type 5Add BLAST39
Zinc fingeri600 – 631MYM-type 6Add BLAST32
Zinc fingeri708 – 742MYM-type 7Add BLAST35
Zinc fingeri749 – 788MYM-type 8Add BLAST40
Zinc fingeri795 – 829MYM-type 9Add BLAST35

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IE8I Eukaryota
ENOG410XQR6 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000159550

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000293258

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG106731

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2A791

Identification of Orthologs from Complete Genome Data

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OMAi
CNQQSMC

Database of Orthologous Groups

More...
OrthoDBi
587724at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2A791

TreeFam database of animal gene trees

More...
TreeFami
TF336988

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR021893 DUF3504
IPR026625 TFII-I-rel
IPR011017 TRASH_dom
IPR010507 Znf_MYM

The PANTHER Classification System

More...
PANTHERi
PTHR11697 PTHR11697, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12012 DUF3504, 1 hit
PF06467 zf-FCS, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00746 TRASH, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: A2A791-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEREVETGP RKRFEQKSDA VFDEIVENCG VMDTEMSEDT DHNLTPTLAS
60 70 80 90 100
MSYGMPNQTG SENSLLDEDD YFLNSGDLAG IPVVSSDNED EQDCSSKDNL
110 120 130 140 150
VSSVHTDGSL EVERRAAHQE SDNENEIQIQ NQLKKDFPKQ FDQVSVFKSI
160 170 180 190 200
RKDFCLVREN SKETFSGKEK NRDLTYHERE KRLDKPHKGL DSRLKSSFFD
210 220 230 240 250
KAANQVEETL HTHLPQNPET NFRDSSYPFA SKESIGSELG NSFASNIRIK
260 270 280 290 300
EEPLDDEYDR AVAPQQGLLD RVKDEPDNAQ EYSHGQQQKT QEGELKISAV
310 320 330 340 350
FSVSGSPLAP QLTTGFQPSL ASPGMNKMLP SVPATAVRVS CSGCKKILQK
360 370 380 390 400
GQTAYQRKGS TQLFCSTLCL TGYTVPPARP PPPLTKKTCS SCSKDILNPK
410 420 430 440 450
DVISAQFENS TTSKDFCSQS CLSTYELKKK PIVTINTNSI STKCSMCQKN
460 470 480 490 500
AVIRHEVNYQ NVVHKLCSDA CFSKFRSANN LTMNCCENCG GYCYSGSGQC
510 520 530 540 550
HVLQIEGQSK KFCSSMCVTS YKQKSAKITP CALCKSLRSS AEMIENTNSL
560 570 580 590 600
GKTELFCSVN CLSAYRVKMV TSAGVQVQCN SCKTSAIPQY HLAMSDGSIR
610 620 630 640 650
NFCSYSCVVA FQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG SSASAGGGST
660 670 680 690 700
PAVSPTSINS SAAAGLQRLA AQSQHVGFAR SVVKLRCQHC NRLFATKPEL
710 720 730 740 750
LDYKGKMFQF CGKNCCDEYK KINNVMAMCE YCKIEKIIKE TVRFSGADKS
760 770 780 790 800
FCSEGCKLLY KHDLGKRWGS HCKMCSYCLQ TSPKLIQNNL GGKVEDFCCE
810 820 830 840 850
ECMSKYTVLF YQMAKCDGCK RQGKLSESLK WRGDIKHFCN LLCILMFCHQ
860 870 880 890 900
QTVCDPPLQN NAVASISMVQ AASAGPPSLR KDSTPVIANV VSLASAPAAQ
910 920 930 940 950
PTANTNSVLQ GAVPTVTAKI IGDASTQTDA LKLPPSQPPR LLKNKALLCK
960 970 980 990 1000
PITQTKATSC KPHTQNKECQ TDTPSEPQVM VVPVPVPVFV PIPLHLYTQY
1010 1020 1030 1040 1050
TPVPFGIPVP MPVPMFIPSS MDNDEKATEG IEDIKEKLAT HPFEADLLEM
1060 1070 1080 1090 1100
AEMIAEDEEK EKTLSQGESQ TSEQELFLDT KIFEKDQGST YSGDLESEAV
1110 1120 1130 1140 1150
STPHSWEEEL NHYALKSNAV QDADSELKPF SKGETEQDLE ADFPSESFDP
1160 1170 1180 1190 1200
LNKGQGIQAR SRTRRRHRDG FPQPRRRGRK KSVVPVEPRS LIQGALQGCS
1210 1220 1230 1240 1250
VSGMTLKYMY GVNAWKNWVQ WKNAKDEQGD LKCGGGELAS ASPCSDSLGS
1260 1270 1280 1290 1300
AQDHALSQES SEQGCKARSV KLKEDILSCT FSELSLGLCQ FIQEVRRPNG
1310 1320 1330 1340 1350
EKYDPDSILY LCLGIQQYLF ENGRIDNIFT EPYSRFMIEL TKLLKIWEPT
1360 1370 1380 1390 1400
ILPNGYMFSR IEEEHLWECK QLGAYSPIVL LNTLLFFNTK YFQLRNVTEH
1410 1420 1430 1440 1450
LKLSFAHVMR RTRTLKYSTK MTYLRFFPPL QKPESEPDKV TIGKRKRNED
1460 1470 1480 1490 1500
DEAPVGVEMA ENTDNPLRCP VRLYEFYLSK CSESVKQRSD VFYLQPERSC
1510 1520 1530 1540
VPNSPMWYST FPIDPGTLDT MLTRILMVRE VHEELAKAKS EDSDAELSD
Length:1,549
Mass (Da):172,438
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i644AF24B4FEB0A62
GO
Isoform 2 (identifier: A2A791-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     524-612: Missing.

Show »
Length:1,460
Mass (Da):162,843
Checksum:i3E9A6B51B6803B9E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6VYE2F6VYE2_MOUSE
Zinc finger MYM-type protein 4
Zmym4
1,209Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC97947 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAM19273 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1357M → V in BAC97947 (PubMed:14621295).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027515524 – 612Missing in isoform 2. 1 PublicationAdd BLAST89

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK129137 mRNA Translation: BAC97947.1 Different initiation.
AL606985, AL606908 Genomic DNA Translation: CAM15585.1
AL606908, AL606985 Genomic DNA Translation: CAM19271.1
AL606908 Genomic DNA Translation: CAM19273.1 Sequence problems.
AK148366 mRNA Translation: BAE28508.1
BC029670 mRNA Translation: AAH29670.1
BC050924 mRNA Translation: AAH50924.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS51303.1 [A2A791-1]

NCBI Reference Sequences

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RefSeqi
NP_001107871.1, NM_001114399.1 [A2A791-1]
XP_006503407.1, XM_006503344.3 [A2A791-2]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.165401

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000106108; ENSMUSP00000101714; ENSMUSG00000042446 [A2A791-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
67785

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:67785

UCSC genome browser

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UCSCi
uc008uty.3 mouse [A2A791-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129137 mRNA Translation: BAC97947.1 Different initiation.
AL606985, AL606908 Genomic DNA Translation: CAM15585.1
AL606908, AL606985 Genomic DNA Translation: CAM19271.1
AL606908 Genomic DNA Translation: CAM19273.1 Sequence problems.
AK148366 mRNA Translation: BAE28508.1
BC029670 mRNA Translation: AAH29670.1
BC050924 mRNA Translation: AAH50924.1
CCDSiCCDS51303.1 [A2A791-1]
RefSeqiNP_001107871.1, NM_001114399.1 [A2A791-1]
XP_006503407.1, XM_006503344.3 [A2A791-2]
UniGeneiMm.165401

3D structure databases

ProteinModelPortaliA2A791
SMRiA2A791
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212440, 1 interactor
IntActiA2A791, 2 interactors
MINTiA2A791
STRINGi10090.ENSMUSP00000101714

PTM databases

iPTMnetiA2A791
PhosphoSitePlusiA2A791

Proteomic databases

jPOSTiA2A791
MaxQBiA2A791
PaxDbiA2A791
PeptideAtlasiA2A791
PRIDEiA2A791

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000106108; ENSMUSP00000101714; ENSMUSG00000042446 [A2A791-1]
GeneIDi67785
KEGGimmu:67785
UCSCiuc008uty.3 mouse [A2A791-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9202
MGIiMGI:1915035 Zmym4

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
Search...

Phylogenomic databases

eggNOGiENOG410IE8I Eukaryota
ENOG410XQR6 LUCA
GeneTreeiENSGT00940000159550
HOGENOMiHOG000293258
HOVERGENiHBG106731
InParanoidiA2A791
OMAiCNQQSMC
OrthoDBi587724at2759
PhylomeDBiA2A791
TreeFamiTF336988

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Zmym4 mouse

Protein Ontology

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PROi
PR:A2A791

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000042446 Expressed in 284 organ(s), highest expression level in embryonic stem cell
ExpressionAtlasiA2A791 baseline and differential
GenevisibleiA2A791 MM

Family and domain databases

InterProiView protein in InterPro
IPR021893 DUF3504
IPR026625 TFII-I-rel
IPR011017 TRASH_dom
IPR010507 Znf_MYM
PANTHERiPTHR11697 PTHR11697, 1 hit
PfamiView protein in Pfam
PF12012 DUF3504, 1 hit
PF06467 zf-FCS, 5 hits
SMARTiView protein in SMART
SM00746 TRASH, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZMYM4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2A791
Secondary accession number(s): Q3UFQ2
, Q6ZQB9, Q80X47, Q8K1H5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: February 20, 2007
Last modified: February 13, 2019
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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