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Protein
Submitted name:

Inducible T-cell co-stimulator

Gene

Icos

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Inducible T-cell co-stimulatorImported
Gene namesi
Name:IcosImported
ORF Names:CH29-120A16.4-001Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei142 – 165HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500264242321 – 200Sequence analysisAdd BLAST180

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 135IGvInterPro annotationAdd BLAST113

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J005 Eukaryota
ENOG41117EH LUCA
HOVERGENiHBG052079
OrthoDBiEOG091G0IRJ

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR039943 ICOS
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
PANTHERiPTHR20904 PTHR20904, 1 hit
PfamiView protein in Pfam
PF15910 V-set_2, 1 hit

Sequencei

Sequence statusi: Complete.

A2A6A7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPYFCHVFV FCFLIRLLTG EINGSADHRM FSFHNGGVQI SCKYPETVQQ
60 70 80 90 100
LKMRLFRERE VLCELTKTKG SGNAVSIKNP MLCLYHLSNN SVSFFLNNPD
110 120 130 140 150
SSQGSYYFCS LSIFDPPPFQ ERNLSGGYLH IYESQLCCQL KLWLPVGCAA
160 170 180 190 200
FVVVLLFGCI LIIWFSKKKY GSSVHDPNSE YMFMAAVNTN KKSRLAGVTS
Length:200
Mass (Da):22,690
Last modified:February 20, 2007 - v1
Checksum:i9B2278E4CAB1DB47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936839 Genomic DNA Translation: CAM13241.1
UniGeneiMm.42044

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR936839 Genomic DNA Translation: CAM13241.1
UniGeneiMm.42044

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410J005 Eukaryota
ENOG41117EH LUCA
HOVERGENiHBG052079
OrthoDBiEOG091G0IRJ

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR039943 ICOS
IPR013783 Ig-like_fold
IPR013106 Ig_V-set
PANTHERiPTHR20904 PTHR20904, 1 hit
PfamiView protein in Pfam
PF15910 V-set_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2A6A7_MOUSE
AccessioniPrimary (citable) accession number: A2A6A7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 7, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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